OTOP1

gene product
This gene encodes a transmembrane protein which belongs to the otopetrin domain protein family and is required for the formation of otoconia and otoliths, calcium carbonate biominerals within the inner ear of mammals that are required for the detection of linear acceleration and gravity. This gene modulates purinergic control of intracellular calcium in vestibular supporting cells. Naturally occurring mutations in the orthologous mouse gene are associated with nonsyndromic otoconia agenesis and a consequent balance defect. The orthologous mouse gene is also induced in white adipose tissue during obesity. The encoded protein is a component of a counterinflammatory pathway that attenuates obesity-induced adipose tissue inflammation and plays an adaptive role in maintaining metabolic homeostasis in obesity. [provided by RefSeq, Jul 2017]
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75 antibodies from 19 providers.

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antibodies-online
10 antibodies
LifeSpan BioSciences, Inc.
23 antibodies
Abnova Corporation
2 antibodies
Aviva Systems Biology
2 antibodies
Novus Biologicals
2 antibodies
OriGene
2 antibodies
Acris Antibodies GmbH
1 antibody
Biorbyt
9 antibodies
Invitrogen Antibodies
2 antibodies
Proteintech Group
1 antibody
NovoPro Bioscience Inc.
1 antibody
Atlas Antibodies
1 antibody
ProSci
1 antibody
Boster Biological Technology
1 antibody
MyBioSource
1 antibody
United States Biological
13 antibodies
Creative Biolabs
1 antibody
Creative Diagnostics
1 antibody
Sigma-Aldrich
1 antibody