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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Western blot [1]
- Immunohistochemistry [4]
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- Product number
- NBP1-86827 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-86827, RRID:AB_11041044
- Product name
- Rabbit Polyclonal LYAR Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human LYAR antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells.
Mutations in Lyar and p53 are synergistically lethal in female mice.
Stadler C, Rexhepaj E, Singan VR, Murphy RF, Pepperkok R, Uhlén M, Simpson JC, Lundberg E
Nature methods 2013 Apr;10(4):315-23
Nature methods 2013 Apr;10(4):315-23
Mutations in Lyar and p53 are synergistically lethal in female mice.
Wang G, Fulkerson CM, Malek R, Ghassemifar S, Snyder PW, Mendrysa SM
Birth defects research. Part A, Clinical and molecular teratology 2012 Sep;94(9):729-37
Birth defects research. Part A, Clinical and molecular teratology 2012 Sep;94(9):729-37
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: LYAR Antibody [NBP1-86827] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: LYAR Antibody [NBP1-86827] - Staining of human testis shows strong nuclear positivity in subsets of cells in seminiferus ducts.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: LYAR Antibody [NBP1-86827] - Staining of human fallopian tube shows low expression as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: LYAR Antibody [NBP1-86827] - Staining of human testis shows high expression.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: LYAR Antibody [NBP1-86827] - Staining in human testis and fallopian tube tissues using anti-LYAR antibody. Corresponding LYAR RNA-seq data are presented for the same tissues.
