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- References [13]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
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- Product number
- 10617-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10617-1-AP, RRID:AB_2127940
- Product name
- ING4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ING4 antibody (Cat. #10617-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inhibition of CK2/ING4 Pathway Facilitates Non-Small Cell Lung Cancer Immunotherapy.
Aberrant CREB1 activation in prostate cancer disrupts normal prostate luminal cell differentiation.
ING4 alleviated lipopolysaccharide-induced inflammation by regulating the NF-κB pathway via a direct interaction with SIRT1.
MicroRNA‑214 upregulates HIF‑1α and VEGF by targeting ING4 in lung cancer cells.
ING4 enhances paclitaxel's effect on colorectal cancer growth in vitro and in vivo.
Transient induction of ING4 by Myc drives prostate epithelial cell differentiation and its disruption drives prostate tumorigenesis.
Expression of hypoxia-inducible factor (HIF)-1a-vascular endothelial growth factor (VEGF)-inhibitory growth factor (ING)-4- axis in sarcoidosis patients.
Downregulated expression of inhibitor of growth 4 (ING4) in advanced colorectal cancers: a non-randomized experimental study.
The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis.
Loss of inhibitor of growth (ING-4) is implicated in the pathogenesis and progression of human astrocytomas.
Down-regulation of the inhibitor of growth family member 4 (ING4) in different forms of pulmonary fibrosis.
The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes.
Role of ING4 in human melanoma cell migration, invasion and patient survival.
Gou Q, Chen H, Chen M, Shi J, Jin J, Liu Q, Hou Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304068
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304068
Aberrant CREB1 activation in prostate cancer disrupts normal prostate luminal cell differentiation.
Watson MJ, Berger PL, Banerjee K, Frank SB, Tang L, Ganguly SS, Hostetter G, Winn M, Miranti CK
Oncogene 2021 May;40(18):3260-3272
Oncogene 2021 May;40(18):3260-3272
ING4 alleviated lipopolysaccharide-induced inflammation by regulating the NF-κB pathway via a direct interaction with SIRT1.
Yang Y, Liu Y, He X, Yang F, Han S, Qin A, Wu G, Liu M, Li Z, Wang J, Yang X, Hu D
Immunology and cell biology 2020 Feb;98(2):127-137
Immunology and cell biology 2020 Feb;98(2):127-137
MicroRNA‑214 upregulates HIF‑1α and VEGF by targeting ING4 in lung cancer cells.
Li Y, Zhao L, Qi Y, Yang X
Molecular medicine reports 2019 Jun;19(6):4935-4945
Molecular medicine reports 2019 Jun;19(6):4935-4945
ING4 enhances paclitaxel's effect on colorectal cancer growth in vitro and in vivo.
Cao L, Chen S, Zhang C, Chen C, Lu N, Jiang Y, Cai Y, Yin Y, Xu J
International journal of clinical and experimental pathology 2015;8(3):2919-27
International journal of clinical and experimental pathology 2015;8(3):2919-27
Transient induction of ING4 by Myc drives prostate epithelial cell differentiation and its disruption drives prostate tumorigenesis.
Berger PL, Frank SB, Schulz VV, Nollet EA, Edick MJ, Holly B, Chang TT, Hostetter G, Kim S, Miranti CK
Cancer research 2014 Jun 15;74(12):3357-68
Cancer research 2014 Jun 15;74(12):3357-68
Expression of hypoxia-inducible factor (HIF)-1a-vascular endothelial growth factor (VEGF)-inhibitory growth factor (ING)-4- axis in sarcoidosis patients.
Tzouvelekis A, Ntolios P, Karameris A, Koutsopoulos A, Boglou P, Koulelidis A, Archontogeorgis K, Zacharis G, Drakopanagiotakis F, Steiropoulos P, Anevlavis S, Polychronopoulos V, Mikroulis D, Bouros D
BMC research notes 2012 Nov 26;5:654
BMC research notes 2012 Nov 26;5:654
Downregulated expression of inhibitor of growth 4 (ING4) in advanced colorectal cancers: a non-randomized experimental study.
You Q, Wang XS, Fu SB, Jin XM
Pathology oncology research : POR 2011 Sep;17(3):473-7
Pathology oncology research : POR 2011 Sep;17(3):473-7
The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis.
Mishima Y, Miyagi S, Saraya A, Negishi M, Endoh M, Endo TA, Toyoda T, Shinga J, Katsumoto T, Chiba T, Yamaguchi N, Kitabayashi I, Koseki H, Iwama A
Blood 2011 Sep 1;118(9):2443-53
Blood 2011 Sep 1;118(9):2443-53
Loss of inhibitor of growth (ING-4) is implicated in the pathogenesis and progression of human astrocytomas.
Klironomos G, Bravou V, Papachristou DJ, Gatzounis G, Varakis J, Parassi E, Repanti M, Papadaki H
Brain pathology (Zurich, Switzerland) 2010 Mar;20(2):490-7
Brain pathology (Zurich, Switzerland) 2010 Mar;20(2):490-7
Down-regulation of the inhibitor of growth family member 4 (ING4) in different forms of pulmonary fibrosis.
Tzouvelekis A, Aidinis V, Harokopos V, Karameris A, Zacharis G, Mikroulis D, Konstantinou F, Steiropoulos P, Sotiriou I, Froudarakis M, Pneumatikos I, Tringidou R, Bouros D
Respiratory research 2009 Feb 27;10(1):14
Respiratory research 2009 Feb 27;10(1):14
The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes.
Nozell S, Laver T, Moseley D, Nowoslawski L, De Vos M, Atkinson GP, Harrison K, Nabors LB, Benveniste EN
Molecular and cellular biology 2008 Nov;28(21):6632-45
Molecular and cellular biology 2008 Nov;28(21):6632-45
Role of ING4 in human melanoma cell migration, invasion and patient survival.
Li J, Martinka M, Li G
Carcinogenesis 2008 Jul;29(7):1373-9
Carcinogenesis 2008 Jul;29(7):1373-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 10617-1-AP(ING4 antibody) at dilution of 1:200
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ING4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ING4. This antibody recognizes human,mouse,rat antigen. The ING4 antibody has been validated for the following applications: ELISA, WB, IP analysis.
