NB300-517

Subramanian A, Capalbo A, Iyengar NR, Rizzo R, di Campli A, Di Martino R, Lo Monte M, Beccari AR, Yerudkar A, Del Vecchio C, Glielmo L, Turacchio G, Pirozzi M, Kim SG, Henklein P, Cancino J, Parashuraman S, Diviani D, Fanelli F, Sallese M, Luini A
Cell 2019 Mar 7;176(6):1461-1476.e23

LRP5 controls cardiac QT interval by modulating the metabolic homeostasis of L-type calcium channel.

Liang D, Wu Y, Zhou L, Chen Y, Liu H, Xie D, Huang J, Zhang Y, Liu Y, Zhu W, Li J, Chen YH
International journal of cardiology 2019 Jan 15;275:120-128

Radical Stress Is More Cytotoxic in the Nucleus than in Other Organelles.

Paardekooper LM, van Vroonhoven E, Ter Beest M, van den Bogaart G
International journal of molecular sciences 2019 Aug 25;20(17)

Myogenic potential of human alveolar mucosa derived cells.

Zorin VL, Pulin AA, Eremin II, Korsakov IN, Zorina AI, Khromova NV, Sokova OI, Kotenko KV, Kopnin PB
Cell cycle (Georgetown, Tex.) 2017 Mar 19;16(6):545-555

Targeting of NADPH oxidase in vitro and in vivo suppresses fibroblast activation and experimental skin fibrosis.

Dosoki H, Stegemann A, Taha M, Schnittler H, Luger TA, Schröder K, Distler JH, Kerkhoff C, Böhm M
Experimental dermatology 2017 Jan;26(1):73-81

Structure-function analyses of microsomal triglyceride transfer protein missense mutations in abetalipoproteinemia and hypobetalipoproteinemia subjects.

Walsh MT, Di Leo E, Okur I, Tarugi P, Hussain MM
Biochimica et biophysica acta 2016 Nov;1861(11):1623-1633

Cell surface protein disulfide isomerase regulates natriuretic peptide generation of cyclic guanosine monophosphate.

Pan S, Chen HH, Correia C, Dai H, Witt TA, Kleppe LS, Burnett JC Jr, Simari RD
PloS one 2014;9(11):e112986

Characterisation of acetylcholinesterase release from neuronal cells.

Hicks DA, Makova NZ, Nalivaeva NN, Turner AJ
Chemico-biological interactions 2013 Mar 25;203(1):302-8

Rapid activation of monocyte tissue factor by antithymocyte globulin is dependent on complement and protein disulfide isomerase.

Langer F, Spath B, Fischer C, Stolz M, Ayuk FA, Kröger N, Bokemeyer C, Ruf W
Blood 2013 Mar 21;121(12):2324-35

Galectin-9 binding to Tim-3 renders activated human CD4+ T cells less susceptible to HIV-1 infection.

Elahi S, Niki T, Hirashima M, Horton H
Blood 2012 May 3;119(18):4192-204

Thrombin-induced shedding of tumour endothelial marker 5 and exposure of its RGD motif are regulated by cell-surface protein disulfide-isomerase.

Vallon M, Aubele P, Janssen KP, Essler M
The Biochemical journal 2012 Feb 1;441(3):937-44

Cytoskeletal remodelling proteins identified in fetal-maternal interface in pregnant women and rhesus monkeys.

Paule S, Li Y, Nie G
Journal of molecular histology 2011 Apr;42(2):161-6

Proteomic approach identifies alterations in cytoskeletal remodelling proteins during decidualization of human endometrial stromal cells.

Paule SG, Airey LM, Li Y, Stephens AN, Nie G
Journal of proteome research 2010 Nov 5;9(11):5739-47

Combined extrinsic and intrinsic manipulations exert complementary neuronal enrichment in embryonic rat neural precursor cultures: an in vitro and in vivo analysis.

Furmanski O, Gajavelli S, Lee JW, Collado ME, Jergova S, Sagen J
The Journal of comparative neurology 2009 Jul 1;515(1):56-71

Neutrophil stress and apoptosis underlie myeloid dysfunction in glycogen storage disease type Ib.

Kim SY, Jun HS, Mead PA, Mansfield BC, Chou JY
Blood 2008 Jun 15;111(12):5704-11

Sustained integrin ligation involves extracellular free sulfhydryls and enzymatically catalyzed disulfide exchange.

Lahav J, Jurk K, Hess O, Barnes MJ, Farndale RW, Luboshitz J, Kehrel BE
Blood 2002 Oct 1;100(7):2472-8

Up-regulation of protein-disulfide isomerase in response to hypoxia/brain ischemia and its protective effect against apoptotic cell death.

Tanaka S, Uehara T, Nomura Y
The Journal of biological chemistry 2000 Apr 7;275(14):10388-93

Up-regulation of protein-disulfide isomerase in response to hypoxia/brain ischemia and its protective effect against apoptotic cell death.

Tanaka S, Uehara T, Nomura Y
The Journal of biological chemistry 2000 Apr 7;275(14):10388-93

Sulfhydryl regulation of L-selectin shedding: phenylarsine oxide promotes activation-independent L-selectin shedding from leukocytes.

Bennett TA, Edwards BS, Sklar LA, Rogelj S
Journal of immunology (Baltimore, Md. : 1950) 2000 Apr 15;164(8):4120-9

Sulfhydryl regulation of L-selectin shedding: phenylarsine oxide promotes activation-independent L-selectin shedding from leukocytes.

Bennett TA, Edwards BS, Sklar LA, Rogelj S
Journal of immunology (Baltimore, Md. : 1950) 2000 Apr 15;164(8):4120-9

Intracellular degradation of the HIV-1 envelope glycoprotein. Evidence for, and some characteristics of, an endoplasmic reticulum degradation pathway.

Courageot J, Fenouillet E, Bastiani P, Miquelis R
European journal of biochemistry 1999 Mar;260(2):482-9

Intracellular degradation of the HIV-1 envelope glycoprotein. Evidence for, and some characteristics of, an endoplasmic reticulum degradation pathway.

Courageot J, Fenouillet E, Bastiani P, Miquelis R
European journal of biochemistry 1999 Mar;260(2):482-9

Inhibition of human immunodeficiency virus infection by agents that interfere with thiol-disulfide interchange upon virus-receptor interaction.

Ryser HJ, Levy EM, Mandel R, DiSciullo GJ
Proceedings of the National Academy of Sciences of the United States of America 1994 May 10;91(10):4559-63

Inhibition of human immunodeficiency virus infection by agents that interfere with thiol-disulfide interchange upon virus-receptor interaction.

Ryser HJ, Levy EM, Mandel R, DiSciullo GJ
Proceedings of the National Academy of Sciences of the United States of America 1994 May 10;91(10):4559-63

Protein disulphide-isomerase from human placenta and rat liver. Purification and immunological characterization with monoclonal antibodies.

Kaetzel CS, Rao CK, Lamm ME
The Biochemical journal 1987 Jan 1;241(1):39-47

Protein disulphide-isomerase from human placenta and rat liver. Purification and immunological characterization with monoclonal antibodies.

Kaetzel CS, Rao CK, Lamm ME
The Biochemical journal 1987 Jan 1;241(1):39-47

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Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Western Blot: PDI Antibody (RL90) [NB300-517] - Analysis of PDI expression in 1) human brain and 2) rat liver tissues extracts, 3) HeLa and 4) Hek 293 whole cell lysates.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Western Blot: PDI Antibody (RL90) [NB300-517] - Analysis of PDI was performed by loading 25 ug of HepG2 (Lane 1), Hela (Lane 2) and NIH-3T3 (Lane 3) cell lysates.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Western Blot: PDI Antibody (RL90) [NB300-517] - Cell surface PDI associated with GC-AC. Proteins were pulled down with anti GC-A antibody from HUVEC or HMC membrane preparations and detected with anti-PDI antibody (RL90)compared to control IP (no anti GC-A) and non-immunoprecipitated proteins from HMC and HUVEC. Image collected and cropped by CiteAb from the following publication (http://dx.plos.org/10.1371/journal.pone.0112986), licensed under a CC-BY licence.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: PDI Antibody (RL90) [NB300-517] - Cancer biopsies of deparaffinized Human lung adenocarcinoma tissues.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: PDI Antibody (RL90) [NB300-517] - Both normal and cancer biopsies of deparaffinized Human colon tissue tissues.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: PDI Antibody (RL90) [NB300-517] - Both normal and cancer biopsies of deparaffinized Human tonsil tissues.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Flow Cytometry: PDI Antibody (RL90) [NB300-517] - Analysis of NIH/3T3 cells compared to an isotype control (blue).

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Flow Cytometry: PDI Antibody (RL90) [NB300-517] - Analysis of Hela cells compared to an isotype control (blue).

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Flow Cytometry: PDI Antibody (RL90) [NB300-517] - Analysis of K562 cells compared to an isotype control (blue).