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- Antibody Data
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- References [57]
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- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 10209-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10209-2-AP, RRID:AB_2080263
- Product name
- CIRBP antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CIRBP antibody (Cat. #10209-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hypoxia causes mitochondrial dysfunction and brain memory disorder in a manner mediated by the reduction of Cirbp.
CIRBP Knockdown Attenuates Tumourigenesis and Improves the Chemosensitivity of Pancreatic Cancer via the Downregulation of DYRK1B.
Cold-inducible RNA-binding protein regulates cyclin B1 against spermatogenesis arrest caused by heat stress.
Deficiency of cold-inducible RNA-binding protein exacerbated monocrotaline-induced pulmonary artery hypertension through Caveolin1 and CAVIN1.
Cold-inducible RNA binding protein agonist enhances the cardioprotective effect of UW solution during extended heart preservation.
Extracellular CIRP as an endogenous TREM-1 ligand to fuel inflammation in sepsis.
Extracellular CIRP induces macrophage endotoxin tolerance through IL-6R-mediated STAT3 activation.
Extracellular microRNA 130b-3p inhibits eCIRP-induced inflammation.
Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection.
Extracellular cold-inducible RNA-binding protein regulates neutrophil extracellular trap formation and tissue damage in acute pancreatitis.
The RNA-Binding Protein RBM3 Promotes Neural Stem Cell (NSC) Proliferation Under Hypoxia.
Loss of Cirbp expression is correlated with the malignant progression and poor prognosis in nasopharyngeal carcinoma.
Association between CIRP expression and hypoxic-ischemic brain injury in neonatal rats.
CIRP downregulation renders cardiac cells prone to apoptosis in heart failure.
Cold-inducible RNA-binding protein as a novel target to alleviate blood-brain barrier damage induced by cardiopulmonary bypass.
Posttranscriptional Regulation of 14q32 MicroRNAs by the CIRBP and HADHB during Vascular Regeneration after Ischemia.
Therapeutic hypothermia protects photoreceptors through activating Cirbp pathway.
An annual cycle of gene regulation in the red-legged salamander mental gland: from hypertrophy to expression of rapidly evolving pheromones.
Expression of cold-inducible RNA-binding protein (CIRP) in renal cell carcinoma and the effect of CIRP downregulation cell proliferation and chemosensitivity to gemcitabine.
iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications.
CIRP increases ICAM-1+ phenotype of neutrophils exhibiting elevated iNOS and NETs in sepsis.
Cold-inducible RNA-binding protein (CIRP) induces translation of the cell-cycle inhibitor p27Kip1.
RNA sequencing and proteomics approaches reveal novel deficits in the cortex of Mecp2-deficient mice, a model for Rett syndrome.
Cold Inducible RNA Binding Protein Is Involved in Chronic Hypoxia Induced Neuron Apoptosis by Down-Regulating HIF-1α Expression and Regulated By microRNA-23a.
Therapeutic Hypothermia Enhances Cold-Inducible RNA-Binding Protein Expression and Inhibits Mitochondrial Apoptosis in a Rat Model of Cardiac Arrest.
Involvement of Cold Inducible RNA-Binding Protein in Severe Hypoxia-Induced Growth Arrest of Neural Stem Cells In Vitro.
Cold-inducible RNA-binding protein mediates airway inflammation and mucus hypersecretion through a post-transcriptional regulatory mechanism under cold stress.
Cold-inducible RNA-binding protein promotes epithelial-mesenchymal transition by activating ERK and p38 pathways.
Cold-inducible RNA-binding protein mediates cold air inducible airway mucin production through TLR4/NF-κB signaling pathway.
Progranulin deficiency leads to severe inflammation, lung injury and cell death in a mouse model of endotoxic shock.
Cold-inducible RNA binding protein in mouse mammary gland development.
Cold-inducible RNA binding protein regulates mucin expression induced by cold temperatures in human airway epithelial cells.
Cooling-induced SUMOylation of EXOSC10 down-regulates ribosome biogenesis.
Cold-inducible RNA-binding protein inhibits neuron apoptosis through the suppression of mitochondrial apoptosis.
Analysis of gene expression profiles reveals the regulatory network of cold-inducible RNA-binding protein mediating the growth of BHK-21 cells.
Hypothermic Preconditioning of Human Cortical Neurons Requires Proteostatic Priming.
Eukaryotic elongation factor 2 kinase regulates the cold stress response by slowing translation elongation.
RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration.
Cold-inducible RNA-binding protein, CIRP, inhibits DNA damage-induced apoptosis by regulating p53.
Cold-inducible RNA-binding protein mediates neuroinflammation in cerebral ischemia.
Protein overexpression of CIRP and TLR4 in oral squamous cell carcinoma: an immunohistochemical and clinical correlation analysis.
NF-κB-dependent role for cold-inducible RNA binding protein in regulating interleukin 1β.
Cold-inducible RNA-binding protein is an important mediator of alcohol-induced brain inflammation.
The protective effect of Cold-inducible RNA-binding protein (CIRP) on testicular torsion/detorsion: an experimental study in mice.
Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis.
Alternative promoters regulate cold inducible RNA-binding (CIRP) gene expression and enhance transgene expression in mammalian cells.
Effects of moderate and deep hypothermia on RNA-binding proteins RBM3 and CIRP expressions in murine hippocampal brain slices.
Cold-inducible RNA-binding protein (CIRP) regulates target mRNA stabilization in the mouse testis.
Downregulation of cold-inducible RNA-binding protein activates mitogen-activated protein kinases and impairs spermatogenic function in mouse testes.
Serum autoantibody signature of ductal carcinoma in situ progression to invasive breast cancer.
Three-dimensional collagen represses cyclin E1 via β1 integrin in invasive breast cancer cells.
Moderate low temperature preserves the stemness of neural stem cells and suppresses apoptosis of the cells via activation of the cold-inducible RNA binding protein.
Cold-inducible RNA-binding protein contributes to human antigen R and cyclin E1 deregulation in breast cancer.
Down-regulating cold shock protein genes impairs cancer cell survival and enhances chemosensitivity.
Cold-inducible RNA binding protein (CIRP) expression is modulated by alternative mRNAs.
Cold-inducible RNA-binding protein bypasses replicative senescence in primary cells through extracellular signal-regulated kinase 1 and 2 activation.
Overexpression of CIRP may reduce testicular damage induced by cryptorchidism.
Liu Y, Xue C, Lu H, Zhou Y, Guan R, Wang J, Zhang Q, Ke T, Aschner M, Zhang W, Luo W
The Science of the total environment 2022 Feb 1;806(Pt 3):151228
The Science of the total environment 2022 Feb 1;806(Pt 3):151228
CIRBP Knockdown Attenuates Tumourigenesis and Improves the Chemosensitivity of Pancreatic Cancer via the Downregulation of DYRK1B.
Chen X, Xie H, Wang X, Zheng Z, Jin S
Frontiers in cell and developmental biology 2021;9:667551
Frontiers in cell and developmental biology 2021;9:667551
Cold-inducible RNA-binding protein regulates cyclin B1 against spermatogenesis arrest caused by heat stress.
Liu H, Xu C, Bao M, Huang J, Zou L, Fan X, Zhu C, Xia W
Andrology 2021 Oct 10;
Andrology 2021 Oct 10;
Deficiency of cold-inducible RNA-binding protein exacerbated monocrotaline-induced pulmonary artery hypertension through Caveolin1 and CAVIN1.
Liu J, Ke X, Wang L, Zhang Y, Yang J
Journal of cellular and molecular medicine 2021 May;25(10):4732-4743
Journal of cellular and molecular medicine 2021 May;25(10):4732-4743
Cold-inducible RNA binding protein agonist enhances the cardioprotective effect of UW solution during extended heart preservation.
Pan HZ, Zhang LJ, Liu YW, Li YN, Su ZH, Meng J, Zhang H
Artificial organs 2020 Oct;44(10):E406-E418
Artificial organs 2020 Oct;44(10):E406-E418
Extracellular CIRP as an endogenous TREM-1 ligand to fuel inflammation in sepsis.
Denning NL, Aziz M, Murao A, Gurien SD, Ochani M, Prince JM, Wang P
JCI insight 2020 Mar 12;5(5)
JCI insight 2020 Mar 12;5(5)
Extracellular CIRP induces macrophage endotoxin tolerance through IL-6R-mediated STAT3 activation.
Zhou M, Aziz M, Denning NL, Yen HT, Ma G, Wang P
JCI insight 2020 Mar 12;5(5)
JCI insight 2020 Mar 12;5(5)
Extracellular microRNA 130b-3p inhibits eCIRP-induced inflammation.
Gurien SD, Aziz M, Jin H, Wang H, He M, Al-Abed Y, Nicastro JM, Coppa GF, Wang P
EMBO reports 2020 Jan 7;21(1):e48075
EMBO reports 2020 Jan 7;21(1):e48075
Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection.
Gokhale NS, McIntyre ABR, Mattocks MD, Holley CL, Lazear HM, Mason CE, Horner SM
Molecular cell 2020 Feb 6;77(3):542-555.e8
Molecular cell 2020 Feb 6;77(3):542-555.e8
Extracellular cold-inducible RNA-binding protein regulates neutrophil extracellular trap formation and tissue damage in acute pancreatitis.
Linders J, Madhi R, Rahman M, Mörgelin M, Regner S, Brenner M, Wang P, Thorlacius H
Laboratory investigation; a journal of technical methods and pathology 2020 Dec;100(12):1618-1630
Laboratory investigation; a journal of technical methods and pathology 2020 Dec;100(12):1618-1630
The RNA-Binding Protein RBM3 Promotes Neural Stem Cell (NSC) Proliferation Under Hypoxia.
Yan J, Goerne T, Zelmer A, Guzman R, Kapfhammer JP, Wellmann S, Zhu X
Frontiers in cell and developmental biology 2019;7:288
Frontiers in cell and developmental biology 2019;7:288
Loss of Cirbp expression is correlated with the malignant progression and poor prognosis in nasopharyngeal carcinoma.
Lin TY, Chen Y, Jia JS, Zhou C, Lian M, Wen YT, Li XY, Chen HW, Lin XL, Zhang XL, Xiao SJ, Sun Y, Xiao D
Cancer management and research 2019;11:6959-6969
Cancer management and research 2019;11:6959-6969
Association between CIRP expression and hypoxic-ischemic brain injury in neonatal rats.
Chen L, Tian Q, Wang W
Experimental and therapeutic medicine 2019 Sep;18(3):1515-1520
Experimental and therapeutic medicine 2019 Sep;18(3):1515-1520
CIRP downregulation renders cardiac cells prone to apoptosis in heart failure.
Chen M, Fu H, Zhang J, Huang H, Zhong P
Biochemical and biophysical research communications 2019 Oct 1;517(4):545-550
Biochemical and biophysical research communications 2019 Oct 1;517(4):545-550
Cold-inducible RNA-binding protein as a novel target to alleviate blood-brain barrier damage induced by cardiopulmonary bypass.
Liu M, Li Y, Liu Y, Yan S, Liu G, Zhang Q, Ji B
The Journal of thoracic and cardiovascular surgery 2019 Mar;157(3):986-996.e5
The Journal of thoracic and cardiovascular surgery 2019 Mar;157(3):986-996.e5
Posttranscriptional Regulation of 14q32 MicroRNAs by the CIRBP and HADHB during Vascular Regeneration after Ischemia.
Downie Ruiz Velasco A, Welten SMJ, Goossens EAC, Quax PHA, Rappsilber J, Michlewski G, Nossent AY
Molecular therapy. Nucleic acids 2019 Mar 1;14:329-338
Molecular therapy. Nucleic acids 2019 Mar 1;14:329-338
Therapeutic hypothermia protects photoreceptors through activating Cirbp pathway.
Sun YJ, Ma S, Fan B, Wang Y, Wang SR, Li GY
Neurochemistry international 2019 Jun;126:86-95
Neurochemistry international 2019 Jun;126:86-95
An annual cycle of gene regulation in the red-legged salamander mental gland: from hypertrophy to expression of rapidly evolving pheromones.
Wilburn DB, Feldhoff RC
BMC developmental biology 2019 Apr 27;19(1):10
BMC developmental biology 2019 Apr 27;19(1):10
Expression of cold-inducible RNA-binding protein (CIRP) in renal cell carcinoma and the effect of CIRP downregulation cell proliferation and chemosensitivity to gemcitabine.
Zhou KW, Jiang K, Zhu W, Weng G
Oncology letters 2018 May;15(5):7611-7616
Oncology letters 2018 May;15(5):7611-7616
iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications.
Ou J, Ball JM, Luan Y, Zhao T, Miyagishima KJ, Xu Y, Zhou H, Chen J, Merriman DK, Xie Z, Mallon BS, Li W
Cell 2018 May 3;173(4):851-863.e16
Cell 2018 May 3;173(4):851-863.e16
CIRP increases ICAM-1+ phenotype of neutrophils exhibiting elevated iNOS and NETs in sepsis.
Ode Y, Aziz M, Wang P
Journal of leukocyte biology 2018 Apr;103(4):693-707
Journal of leukocyte biology 2018 Apr;103(4):693-707
Cold-inducible RNA-binding protein (CIRP) induces translation of the cell-cycle inhibitor p27Kip1.
Roilo M, Kullmann MK, Hengst L
Nucleic acids research 2018 Apr 6;46(6):3198-3210
Nucleic acids research 2018 Apr 6;46(6):3198-3210
RNA sequencing and proteomics approaches reveal novel deficits in the cortex of Mecp2-deficient mice, a model for Rett syndrome.
Pacheco NL, Heaven MR, Holt LM, Crossman DK, Boggio KJ, Shaffer SA, Flint DL, Olsen ML
Molecular autism 2017;8:56
Molecular autism 2017;8:56
Cold Inducible RNA Binding Protein Is Involved in Chronic Hypoxia Induced Neuron Apoptosis by Down-Regulating HIF-1α Expression and Regulated By microRNA-23a.
Chen X, Liu X, Li B, Zhang Q, Wang J, Zhang W, Luo W, Chen J
International journal of biological sciences 2017;13(4):518-531
International journal of biological sciences 2017;13(4):518-531
Therapeutic Hypothermia Enhances Cold-Inducible RNA-Binding Protein Expression and Inhibits Mitochondrial Apoptosis in a Rat Model of Cardiac Arrest.
Wu L, Sun HL, Gao Y, Hui KL, Xu MM, Zhong H, Duan ML
Molecular neurobiology 2017 May;54(4):2697-2705
Molecular neurobiology 2017 May;54(4):2697-2705
Involvement of Cold Inducible RNA-Binding Protein in Severe Hypoxia-Induced Growth Arrest of Neural Stem Cells In Vitro.
Zhang Q, Wang YZ, Zhang W, Chen X, Wang J, Chen J, Luo W
Molecular neurobiology 2017 Apr;54(3):2143-2153
Molecular neurobiology 2017 Apr;54(3):2143-2153
Cold-inducible RNA-binding protein mediates airway inflammation and mucus hypersecretion through a post-transcriptional regulatory mechanism under cold stress.
Juan Y, Haiqiao W, Xie W, Huaping H, Zhong H, Xiangdong Z, Kolosov VP, Perelman JM
The international journal of biochemistry & cell biology 2016 Sep;78:335-348
The international journal of biochemistry & cell biology 2016 Sep;78:335-348
Cold-inducible RNA-binding protein promotes epithelial-mesenchymal transition by activating ERK and p38 pathways.
Lee HN, Ahn SM, Jang HH
Biochemical and biophysical research communications 2016 Sep 2;477(4):1038-1044
Biochemical and biophysical research communications 2016 Sep 2;477(4):1038-1044
Cold-inducible RNA-binding protein mediates cold air inducible airway mucin production through TLR4/NF-κB signaling pathway.
Chen L, Ran D, Xie W, Xu Q, Zhou X
International immunopharmacology 2016 Oct;39:48-56
International immunopharmacology 2016 Oct;39:48-56
Progranulin deficiency leads to severe inflammation, lung injury and cell death in a mouse model of endotoxic shock.
Yu Y, Xu X, Liu L, Mao S, Feng T, Lu Y, Cheng Y, Wang H, Zhao W, Tang W
Journal of cellular and molecular medicine 2016 Mar;20(3):506-17
Journal of cellular and molecular medicine 2016 Mar;20(3):506-17
Cold-inducible RNA binding protein in mouse mammary gland development.
Lujan DA, Garcia S, Vanderhoof J, Sifuentes J, Brandt Y, Wu Y, Guo X, Mitchell T, Howard T, Hathaway HJ, Hartley RS
Tissue & cell 2016 Dec;48(6):577-587
Tissue & cell 2016 Dec;48(6):577-587
Cold-inducible RNA binding protein regulates mucin expression induced by cold temperatures in human airway epithelial cells.
Ran D, Chen L, Xie W, Xu Q, Han Z, Huang H, Zhou X
Archives of biochemistry and biophysics 2016 Aug 1;603:81-90
Archives of biochemistry and biophysics 2016 Aug 1;603:81-90
Cooling-induced SUMOylation of EXOSC10 down-regulates ribosome biogenesis.
Knight JR, Bastide A, Peretti D, Roobol A, Roobol J, Mallucci GR, Smales CM, Willis AE
RNA (New York, N.Y.) 2016 Apr;22(4):623-35
RNA (New York, N.Y.) 2016 Apr;22(4):623-35
Cold-inducible RNA-binding protein inhibits neuron apoptosis through the suppression of mitochondrial apoptosis.
Zhang HT, Xue JH, Zhang ZW, Kong HB, Liu AJ, Li SC, Xu DG
Brain research 2015 Oct 5;1622:474-83
Brain research 2015 Oct 5;1622:474-83
Analysis of gene expression profiles reveals the regulatory network of cold-inducible RNA-binding protein mediating the growth of BHK-21 cells.
Tang C, Wang Y, Lan D, Feng X, Zhu X, Nie P, Yue H
Cell biology international 2015 Jun;39(6):678-89
Cell biology international 2015 Jun;39(6):678-89
Hypothermic Preconditioning of Human Cortical Neurons Requires Proteostatic Priming.
Rzechorzek NM, Connick P, Patani R, Selvaraj BT, Chandran S
EBioMedicine 2015 Jun;2(6):528-35
EBioMedicine 2015 Jun;2(6):528-35
Eukaryotic elongation factor 2 kinase regulates the cold stress response by slowing translation elongation.
Knight JR, Bastide A, Roobol A, Roobol J, Jackson TJ, Utami W, Barrett DA, Smales CM, Willis AE
The Biochemical journal 2015 Jan 15;465(2):227-38
The Biochemical journal 2015 Jan 15;465(2):227-38
RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration.
Peretti D, Bastide A, Radford H, Verity N, Molloy C, Martin MG, Moreno JA, Steinert JR, Smith T, Dinsdale D, Willis AE, Mallucci GR
Nature 2015 Feb 12;518(7538):236-9
Nature 2015 Feb 12;518(7538):236-9
Cold-inducible RNA-binding protein, CIRP, inhibits DNA damage-induced apoptosis by regulating p53.
Lee HN, Ahn SM, Jang HH
Biochemical and biophysical research communications 2015 Aug 28;464(3):916-21
Biochemical and biophysical research communications 2015 Aug 28;464(3):916-21
Cold-inducible RNA-binding protein mediates neuroinflammation in cerebral ischemia.
Zhou M, Yang WL, Ji Y, Qiang X, Wang P
Biochimica et biophysica acta 2014 Jul;1840(7):2253-61
Biochimica et biophysica acta 2014 Jul;1840(7):2253-61
Protein overexpression of CIRP and TLR4 in oral squamous cell carcinoma: an immunohistochemical and clinical correlation analysis.
Ren WH, Zhang LM, Liu HQ, Gao L, Chen C, Qiang C, Wang XL, Liu CY, Li SM, Huang C, Qi H, Zhi KQ
Medical oncology (Northwood, London, England) 2014 Aug;31(8):120
Medical oncology (Northwood, London, England) 2014 Aug;31(8):120
NF-κB-dependent role for cold-inducible RNA binding protein in regulating interleukin 1β.
Brochu C, Cabrita MA, Melanson BD, Hamill JD, Lau R, Pratt MA, McKay BC
PloS one 2013;8(2):e57426
PloS one 2013;8(2):e57426
Cold-inducible RNA-binding protein is an important mediator of alcohol-induced brain inflammation.
Rajayer SR, Jacob A, Yang WL, Zhou M, Chaung W, Wang P
PloS one 2013;8(11):e79430
PloS one 2013;8(11):e79430
The protective effect of Cold-inducible RNA-binding protein (CIRP) on testicular torsion/detorsion: an experimental study in mice.
Xia Z, Jiang K, Liu T, Zheng H, Liu X, Zheng X
Journal of pediatric surgery 2013 Oct;48(10):2140-7
Journal of pediatric surgery 2013 Oct;48(10):2140-7
Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis.
Qiang X, Yang WL, Wu R, Zhou M, Jacob A, Dong W, Kuncewitch M, Ji Y, Yang H, Wang H, Fujita J, Nicastro J, Coppa GF, Tracey KJ, Wang P
Nature medicine 2013 Nov;19(11):1489-1495
Nature medicine 2013 Nov;19(11):1489-1495
Alternative promoters regulate cold inducible RNA-binding (CIRP) gene expression and enhance transgene expression in mammalian cells.
Al-Fageeh MB, Smales CM
Molecular biotechnology 2013 Jun;54(2):238-49
Molecular biotechnology 2013 Jun;54(2):238-49
Effects of moderate and deep hypothermia on RNA-binding proteins RBM3 and CIRP expressions in murine hippocampal brain slices.
Tong G, Endersfelder S, Rosenthal LM, Wollersheim S, Sauer IM, Bührer C, Berger F, Schmitt KR
Brain research 2013 Apr 4;1504:74-84
Brain research 2013 Apr 4;1504:74-84
Cold-inducible RNA-binding protein (CIRP) regulates target mRNA stabilization in the mouse testis.
Xia Z, Zheng X, Zheng H, Liu X, Yang Z, Wang X
FEBS letters 2012 Sep 21;586(19):3299-308
FEBS letters 2012 Sep 21;586(19):3299-308
Downregulation of cold-inducible RNA-binding protein activates mitogen-activated protein kinases and impairs spermatogenic function in mouse testes.
Xia ZP, Zheng XM, Zheng H, Liu XJ, Liu GY, Wang XH
Asian journal of andrology 2012 Nov;14(6):884-9
Asian journal of andrology 2012 Nov;14(6):884-9
Serum autoantibody signature of ductal carcinoma in situ progression to invasive breast cancer.
Mangé A, Lacombe J, Bascoul-Mollevi C, Jarlier M, Lamy PJ, Rouanet P, Maudelonde T, Solassol J
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Apr 1;18(7):1992-2000
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Apr 1;18(7):1992-2000
Three-dimensional collagen represses cyclin E1 via β1 integrin in invasive breast cancer cells.
Wu Y, Guo X, Brandt Y, Hathaway HJ, Hartley RS
Breast cancer research and treatment 2011 Jun;127(2):397-406
Breast cancer research and treatment 2011 Jun;127(2):397-406
Moderate low temperature preserves the stemness of neural stem cells and suppresses apoptosis of the cells via activation of the cold-inducible RNA binding protein.
Saito K, Fukuda N, Matsumoto T, Iribe Y, Tsunemi A, Kazama T, Yoshida-Noro C, Hayashi N
Brain research 2010 Oct 28;1358:20-9
Brain research 2010 Oct 28;1358:20-9
Cold-inducible RNA-binding protein contributes to human antigen R and cyclin E1 deregulation in breast cancer.
Guo X, Wu Y, Hartley RS
Molecular carcinogenesis 2010 Feb;49(2):130-40
Molecular carcinogenesis 2010 Feb;49(2):130-40
Down-regulating cold shock protein genes impairs cancer cell survival and enhances chemosensitivity.
Zeng Y, Kulkarni P, Inoue T, Getzenberg RH
Journal of cellular biochemistry 2009 May 1;107(1):179-88
Journal of cellular biochemistry 2009 May 1;107(1):179-88
Cold-inducible RNA binding protein (CIRP) expression is modulated by alternative mRNAs.
Al-Fageeh MB, Smales CM
RNA (New York, N.Y.) 2009 Jun;15(6):1164-76
RNA (New York, N.Y.) 2009 Jun;15(6):1164-76
Cold-inducible RNA-binding protein bypasses replicative senescence in primary cells through extracellular signal-regulated kinase 1 and 2 activation.
Artero-Castro A, Callejas FB, Castellvi J, Kondoh H, Carnero A, Fernández-Marcos PJ, Serrano M, Ramón y Cajal S, Lleonart ME
Molecular and cellular biology 2009 Apr;29(7):1855-68
Molecular and cellular biology 2009 Apr;29(7):1855-68
Overexpression of CIRP may reduce testicular damage induced by cryptorchidism.
Zhou KW, Zheng XM, Yang ZW, Zhang L, Chen HD
Clinical and investigative medicine. Medecine clinique et experimentale 2009 Apr 1;32(2):E103-11
Clinical and investigative medicine. Medecine clinique et experimentale 2009 Apr 1;32(2):E103-11
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 10209-2-AP(CIRBP antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CIRBP antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CIRBP. This antibody recognizes human, mouse antigen. The CIRBP antibody has been validated for the following applications: ELISA, IHC, IP, WB, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-CIRBP (IP:10209-2-AP, 3ug; Detection:10209-2-AP 1:500) with HepG2 cells lysate 6000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 10209-2-AP(CIRBP antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
