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- Antibody Data
- Antigen structure
- References [58]
- Comments [0]
- Validations
- Western blot [2]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 11558-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11558-1-AP, RRID:AB_2216046
- Product name
- WFS1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated WFS1 antibody (Cat. #11558-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Entorhinal cortical Island cells regulate temporal association learning with long trace period.
Overexpression of Lin28A in neural progenitor cells in vivo does not lead to brain tumor formation but results in reduced spine density.
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Sublayer- and cell-type-specific neurodegenerative transcriptional trajectories in hippocampal sclerosis.
Novel role for mineralocorticoid receptors in control of a neuronal phenotype.
Corneal Abnormalities Are Novel Clinical Feature in Wolfram Syndrome.
A soluble endoplasmic reticulum factor as regenerative therapy for Wolfram syndrome.
Septal GABAergic inputs to CA1 govern contextual memory retrieval.
Hippocampal CA2 Organizes CA1 Slow and Fast γ Oscillations during Novel Social and Object Interaction.
Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model.
Monosomes actively translate synaptic mRNAs in neuronal processes.
Unexpected Rule-Changes in a Working Memory Task Shape the Firing of Histologically Identified Delay-Tuned Neurons in the Prefrontal Cortex.
Layer 3 Pyramidal Cells in the Medial Entorhinal Cortex Orchestrate Up-Down States and Entrain the Deep Layers Differentially.
Somatostatin expressing GABAergic interneurons in the medial entorhinal cortex preferentially inhibit layerIII-V pyramidal cells.
Multiple Retinal Anomalies in Wfs1-Deficient Mice.
Ipsi- and contralateral corticocortical projection-dependent subcircuits in layer 2 of the rat frontal cortex.
Electrophysiological and Molecular Characterization of the Parasubiculum.
A Hippocampus-Accumbens Tripartite Neuronal Motif Guides Appetitive Memory in Space.
Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity.
Proximodistal Organization of the CA2 Hippocampal Area.
The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration.
Serotonin receptor 2c-expressing cells in the ventral CA1 control attention via innervation of the Edinger-Westphal nucleus.
Recurrent circuits within medial entorhinal cortex superficial layers support grid cell firing.
A Map-like Micro-Organization of Grid Cells in the Medial Entorhinal Cortex.
RGS14 Restricts Plasticity in Hippocampal CA2 by Limiting Postsynaptic Calcium Signaling.
Dorsal CA1 interneurons contribute to acute stress-induced spatial memory deficits.
A Visual-Cue-Dependent Memory Circuit for Place Navigation.
Expression of channelrhodopsin-2 localized within the deep CA1 hippocampal sublayer in the Thy1 line 18 mouse.
Distribution of HAP1-immunoreactive Cells in the Retrosplenial-retrohippocampal Area of Adult Rat Brain and Its Application to a Refined Neuroanatomical Understanding of the Region.
Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.
Shared rhythmic subcortical GABAergic input to the entorhinal cortex and presubiculum.
Complementary Modular Microcircuits of the Rat Medial Entorhinal Cortex.
SPIN90 Modulates Long-Term Depression and Behavioral Flexibility in the Hippocampus.
A Whole-Genome RNA Interference Screen Reveals a Role for Spry2 in Insulin Transcription and the Unfolded Protein Response.
Glutamatergic synaptic integration of locomotion speed via septoentorhinal projections.
Distinct Neural Circuits for the Formation and Retrieval of Episodic Memories.
Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology.
Satb2 determines miRNA expression and long-term memory in the adult central nervous system.
Anatomical organization of presubicular head-direction circuits.
Spatially segregated feedforward and feedback neurons support differential odor processing in the lateral entorhinal cortex.
Cell Type-Specific Differences in Spike Timing and Spike Shape in the Rat Parasubiculum and Superficial Medial Entorhinal Cortex.
Local and Distant Input Controlling Excitation in Layer II of the Medial Entorhinal Cortex.
Structural development and dorsoventral maturation of the medial entorhinal cortex.
Determinants of different deep and superficial CA1 pyramidal cell dynamics during sharp-wave ripples.
Entorhinal Cortical Ocean Cells Encode Specific Contexts and Drive Context-Specific Fear Memory.
IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions.
Distinct speed dependence of entorhinal island and ocean cells, including respective grid cells.
ATF6β regulates the Wfs1 gene and has a cell survival role in the ER stress response in pancreatic β-cells.
Sarco(endo)plasmic reticulum ATPase is a molecular partner of Wolfram syndrome 1 protein, which negatively regulates its expression.
Synaptic Targets of Medial Septal Projections in the Hippocampus and Extrahippocampal Cortices of the Mouse.
Calcium efflux from the endoplasmic reticulum leads to β-cell death.
Cell type-specific genetic and optogenetic tools reveal hippocampal CA2 circuits.
Island cells control temporal association memory.
A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome.
The hippocampal CA2 region is essential for social memory.
Autosomal dominant diabetes arising from a Wolfram syndrome 1 mutation.
Oligomerised lychee fruit-derived polyphenol attenuates cognitive impairment in senescence-accelerated mice and endoplasmic reticulum stress in neuronal cells.
Vacuolar-type H+-ATPase V1A subunit is a molecular partner of Wolfram syndrome 1 (WFS1) protein, which regulates its expression and stability.
Yokose J, Marks WD, Yamamoto N, Ogawa SK, Kitamura T
Learning & memory (Cold Spring Harbor, N.Y.) 2021 Sep;28(9):319-328
Learning & memory (Cold Spring Harbor, N.Y.) 2021 Sep;28(9):319-328
Overexpression of Lin28A in neural progenitor cells in vivo does not lead to brain tumor formation but results in reduced spine density.
Middelkamp M, Ruck L, Krisp C, Sumisławski P, Mohammadi B, Dottermusch M, Meister V, Küster L, Schlüter H, Windhorst S, Neumann JE
Acta neuropathologica communications 2021 Nov 20;9(1):185
Acta neuropathologica communications 2021 Nov 20;9(1):185
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Wu X, Sheng H, Wang L, Xia P, Wang Y, Yu L, Lv W, Hu J
Aging 2021 Mar 26;13(7):10034-10057
Aging 2021 Mar 26;13(7):10034-10057
Sublayer- and cell-type-specific neurodegenerative transcriptional trajectories in hippocampal sclerosis.
Cid E, Marquez-Galera A, Valero M, Gal B, Medeiros DC, Navarron CM, Ballesteros-Esteban L, Reig-Viader R, Morales AV, Fernandez-Lamo I, Gomez-Dominguez D, Sato M, Hayashi Y, Bayés À, Barco A, Lopez-Atalaya JP, de la Prida LM
Cell reports 2021 Jun 8;35(10):109229
Cell reports 2021 Jun 8;35(10):109229
Novel role for mineralocorticoid receptors in control of a neuronal phenotype.
McCann KE, Lustberg DJ, Shaughnessy EK, Carstens KE, Farris S, Alexander GM, Radzicki D, Zhao M, Dudek SM
Molecular psychiatry 2021 Jan;26(1):350-364
Molecular psychiatry 2021 Jan;26(1):350-364
Corneal Abnormalities Are Novel Clinical Feature in Wolfram Syndrome.
Waszczykowska A, Zmysłowska A, Braun M, Zielonka E, Ivask M, Koks S, Jurowski P, Młynarski W
American journal of ophthalmology 2020 Sep;217:140-151
American journal of ophthalmology 2020 Sep;217:140-151
A soluble endoplasmic reticulum factor as regenerative therapy for Wolfram syndrome.
Mahadevan J, Morikawa S, Yagi T, Abreu D, Lu S, Kanekura K, Brown CM, Urano F
Laboratory investigation; a journal of technical methods and pathology 2020 Sep;100(9):1197-1207
Laboratory investigation; a journal of technical methods and pathology 2020 Sep;100(9):1197-1207
Septal GABAergic inputs to CA1 govern contextual memory retrieval.
Sans-Dublanc A, Razzauti A, Desikan S, Pascual M, Monyer H, Sindreu C
Science advances 2020 Oct;6(44)
Science advances 2020 Oct;6(44)
Hippocampal CA2 Organizes CA1 Slow and Fast γ Oscillations during Novel Social and Object Interaction.
Brown LY, Alexander GM, Cushman J, Dudek SM
eNeuro 2020 Mar Apr;7(2)
eNeuro 2020 Mar Apr;7(2)
Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model.
Rice HC, Marcassa G, Chrysidou I, Horré K, Young-Pearse TL, Müller UC, Saito T, Saido TC, Vassar R, de Wit J, De Strooper B
Molecular neurodegeneration 2020 Jan 8;15(1):3
Molecular neurodegeneration 2020 Jan 8;15(1):3
Monosomes actively translate synaptic mRNAs in neuronal processes.
Biever A, Glock C, Tushev G, Ciirdaeva E, Dalmay T, Langer JD, Schuman EM
Science (New York, N.Y.) 2020 Jan 31;367(6477)
Science (New York, N.Y.) 2020 Jan 31;367(6477)
Unexpected Rule-Changes in a Working Memory Task Shape the Firing of Histologically Identified Delay-Tuned Neurons in the Prefrontal Cortex.
Ozdemir AT, Lagler M, Lagoun S, Malagon-Vina H, Lasztóczi B, Klausberger T
Cell reports 2020 Feb 4;30(5):1613-1626.e4
Cell reports 2020 Feb 4;30(5):1613-1626.e4
Layer 3 Pyramidal Cells in the Medial Entorhinal Cortex Orchestrate Up-Down States and Entrain the Deep Layers Differentially.
Beed P, de Filippo R, Holman C, Johenning FW, Leibold C, Caputi A, Monyer H, Schmitz D
Cell reports 2020 Dec 8;33(10):108470
Cell reports 2020 Dec 8;33(10):108470
Somatostatin expressing GABAergic interneurons in the medial entorhinal cortex preferentially inhibit layerIII-V pyramidal cells.
Kecskés M, Henn-Mike N, Agócs-Laboda Á, Szőcs S, Petykó Z, Varga C
Communications biology 2020 Dec 10;3(1):754
Communications biology 2020 Dec 10;3(1):754
Multiple Retinal Anomalies in Wfs1-Deficient Mice.
Waszczykowska A, Zmysłowska A, Braun M, Ivask M, Koks S, Jurowski P, Młynarski W
Diagnostics (Basel, Switzerland) 2020 Aug 19;10(9)
Diagnostics (Basel, Switzerland) 2020 Aug 19;10(9)
Ipsi- and contralateral corticocortical projection-dependent subcircuits in layer 2 of the rat frontal cortex.
Ueta Y, Sohn J, Agahari FA, Im S, Hirai Y, Miyata M, Kawaguchi Y
Journal of neurophysiology 2019 Oct 1;122(4):1461-1472
Journal of neurophysiology 2019 Oct 1;122(4):1461-1472
Electrophysiological and Molecular Characterization of the Parasubiculum.
Sammons RP, Parthier D, Stumpf A, Schmitz D
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Nov 6;39(45):8860-8876
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Nov 6;39(45):8860-8876
A Hippocampus-Accumbens Tripartite Neuronal Motif Guides Appetitive Memory in Space.
Trouche S, Koren V, Doig NM, Ellender TJ, El-Gaby M, Lopes-Dos-Santos V, Reeve HM, Perestenko PV, Garas FN, Magill PJ, Sharott A, Dupret D
Cell 2019 Mar 7;176(6):1393-1406.e16
Cell 2019 Mar 7;176(6):1393-1406.e16
Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity.
Hu D, Sun X, Liao X, Zhang X, Zarabi S, Schimmer A, Hong Y, Ford C, Luo Y, Qi X
Acta neuropathologica 2019 Jun;137(6):939-960
Acta neuropathologica 2019 Jun;137(6):939-960
Proximodistal Organization of the CA2 Hippocampal Area.
Fernandez-Lamo I, Gomez-Dominguez D, Sanchez-Aguilera A, Oliva A, Morales AV, Valero M, Cid E, Berenyi A, Menendez de la Prida L
Cell reports 2019 Feb 12;26(7):1734-1746.e6
Cell reports 2019 Feb 12;26(7):1734-1746.e6
The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration.
Schoof M, Launspach M, Holdhof D, Nguyen L, Engel V, Filser S, Peters F, Immenschuh J, Hellwig M, Niesen J, Mall V, Ertl-Wagner B, Hagel C, Spohn M, Lutz B, Sedlacik J, Indenbirken D, Merk DJ, Schüller U
Acta neuropathologica communications 2019 Dec 5;7(1):199
Acta neuropathologica communications 2019 Dec 5;7(1):199
Serotonin receptor 2c-expressing cells in the ventral CA1 control attention via innervation of the Edinger-Westphal nucleus.
Li X, Chen W, Pan K, Li H, Pang P, Guo Y, Shu S, Cai Y, Pei L, Liu D, Afewerky HK, Tian Q, Zhu LQ, Lu Y
Nature neuroscience 2018 Sep;21(9):1239-1250
Nature neuroscience 2018 Sep;21(9):1239-1250
Recurrent circuits within medial entorhinal cortex superficial layers support grid cell firing.
Zutshi I, Fu ML, Lilascharoen V, Leutgeb JK, Lim BK, Leutgeb S
Nature communications 2018 Sep 12;9(1):3701
Nature communications 2018 Sep 12;9(1):3701
A Map-like Micro-Organization of Grid Cells in the Medial Entorhinal Cortex.
Gu Y, Lewallen S, Kinkhabwala AA, Domnisoru C, Yoon K, Gauthier JL, Fiete IR, Tank DW
Cell 2018 Oct 18;175(3):736-750.e30
Cell 2018 Oct 18;175(3):736-750.e30
RGS14 Restricts Plasticity in Hippocampal CA2 by Limiting Postsynaptic Calcium Signaling.
Evans PR, Parra-Bueno P, Smirnov MS, Lustberg DJ, Dudek SM, Hepler JR, Yasuda R
eNeuro 2018 May-Jun;5(3)
eNeuro 2018 May-Jun;5(3)
Dorsal CA1 interneurons contribute to acute stress-induced spatial memory deficits.
Yu JY, Fang P, Wang C, Wang XX, Li K, Gong Q, Luo BY, Wang XD
Neuropharmacology 2018 Jun;135:474-486
Neuropharmacology 2018 Jun;135:474-486
A Visual-Cue-Dependent Memory Circuit for Place Navigation.
Qin H, Fu L, Hu B, Liao X, Lu J, He W, Liang S, Zhang K, Li R, Yao J, Yan J, Chen H, Jia H, Zott B, Konnerth A, Chen X
Neuron 2018 Jul 11;99(1):47-55.e4
Neuron 2018 Jul 11;99(1):47-55.e4
Expression of channelrhodopsin-2 localized within the deep CA1 hippocampal sublayer in the Thy1 line 18 mouse.
Dobbins DL, Klorig DC, Smith T, Godwin DW
Brain research 2018 Jan 15;1679:179-184
Brain research 2018 Jan 15;1679:179-184
Distribution of HAP1-immunoreactive Cells in the Retrosplenial-retrohippocampal Area of Adult Rat Brain and Its Application to a Refined Neuroanatomical Understanding of the Region.
Wroblewski G, Islam MN, Yanai A, Jahan MR, Masumoto KH, Shinoda K
Neuroscience 2018 Dec 1;394:109-126
Neuroscience 2018 Dec 1;394:109-126
Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.
Evans PR, Gerber KJ, Dammer EB, Duong DM, Goswami D, Lustberg DJ, Zou J, Yang JJ, Dudek SM, Griffin PR, Seyfried NT, Hepler JR
Journal of proteome research 2018 Apr 6;17(4):1700-1711
Journal of proteome research 2018 Apr 6;17(4):1700-1711
Shared rhythmic subcortical GABAergic input to the entorhinal cortex and presubiculum.
Viney TJ, Salib M, Joshi A, Unal G, Berry N, Somogyi P
eLife 2018 Apr 5;7
eLife 2018 Apr 5;7
Complementary Modular Microcircuits of the Rat Medial Entorhinal Cortex.
Ray S, Burgalossi A, Brecht M, Naumann RK
Frontiers in systems neuroscience 2017;11:20
Frontiers in systems neuroscience 2017;11:20
SPIN90 Modulates Long-Term Depression and Behavioral Flexibility in the Hippocampus.
Kim DH, Kang M, Kim CH, Huh YH, Cho IH, Ryu HH, Chung KH, Park CS, Rhee S, Lee YS, Song WK
Frontiers in molecular neuroscience 2017;10:295
Frontiers in molecular neuroscience 2017;10:295
A Whole-Genome RNA Interference Screen Reveals a Role for Spry2 in Insulin Transcription and the Unfolded Protein Response.
Pappalardo Z, Gambhir Chopra D, Hennings TG, Richards H, Choe J, Yang K, Baeyens L, Ang K, Chen S, Arkin M, German MS, McManus MT, Ku GM
Diabetes 2017 Jun;66(6):1703-1712
Diabetes 2017 Jun;66(6):1703-1712
Glutamatergic synaptic integration of locomotion speed via septoentorhinal projections.
Justus D, Dalügge D, Bothe S, Fuhrmann F, Hannes C, Kaneko H, Friedrichs D, Sosulina L, Schwarz I, Elliott DA, Schoch S, Bradke F, Schwarz MK, Remy S
Nature neuroscience 2017 Jan;20(1):16-19
Nature neuroscience 2017 Jan;20(1):16-19
Distinct Neural Circuits for the Formation and Retrieval of Episodic Memories.
Roy DS, Kitamura T, Okuyama T, Ogawa SK, Sun C, Obata Y, Yoshiki A, Tonegawa S
Cell 2017 Aug 24;170(5):1000-1012.e19
Cell 2017 Aug 24;170(5):1000-1012.e19
Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology.
Le Thanh P, Meinke P, Korfali N, Srsen V, Robson MI, Wehnert M, Schoser B, Sewry CA, Schirmer EC
Neuromuscular disorders : NMD 2017 Apr;27(4):338-351
Neuromuscular disorders : NMD 2017 Apr;27(4):338-351
Satb2 determines miRNA expression and long-term memory in the adult central nervous system.
Jaitner C, Reddy C, Abentung A, Whittle N, Rieder D, Delekate A, Korte M, Jain G, Fischer A, Sananbenesi F, Cera I, Singewald N, Dechant G, Apostolova G
eLife 2016 Nov 29;5
eLife 2016 Nov 29;5
Anatomical organization of presubicular head-direction circuits.
Preston-Ferrer P, Coletta S, Frey M, Burgalossi A
eLife 2016 Jun 10;5
eLife 2016 Jun 10;5
Spatially segregated feedforward and feedback neurons support differential odor processing in the lateral entorhinal cortex.
Leitner FC, Melzer S, Lütcke H, Pinna R, Seeburg PH, Helmchen F, Monyer H
Nature neuroscience 2016 Jul;19(7):935-44
Nature neuroscience 2016 Jul;19(7):935-44
Cell Type-Specific Differences in Spike Timing and Spike Shape in the Rat Parasubiculum and Superficial Medial Entorhinal Cortex.
Ebbesen CL, Reifenstein ET, Tang Q, Burgalossi A, Ray S, Schreiber S, Kempter R, Brecht M
Cell reports 2016 Jul 26;16(4):1005-1015
Cell reports 2016 Jul 26;16(4):1005-1015
Local and Distant Input Controlling Excitation in Layer II of the Medial Entorhinal Cortex.
Fuchs EC, Neitz A, Pinna R, Melzer S, Caputi A, Monyer H
Neuron 2016 Jan 6;89(1):194-208
Neuron 2016 Jan 6;89(1):194-208
Structural development and dorsoventral maturation of the medial entorhinal cortex.
Ray S, Brecht M
eLife 2016 Apr 2;5:e13343
eLife 2016 Apr 2;5:e13343
Determinants of different deep and superficial CA1 pyramidal cell dynamics during sharp-wave ripples.
Valero M, Cid E, Averkin RG, Aguilar J, Sanchez-Aguilera A, Viney TJ, Gomez-Dominguez D, Bellistri E, de la Prida LM
Nature neuroscience 2015 Sep;18(9):1281-1290
Nature neuroscience 2015 Sep;18(9):1281-1290
Entorhinal Cortical Ocean Cells Encode Specific Contexts and Drive Context-Specific Fear Memory.
Kitamura T, Sun C, Martin J, Kitch LJ, Schnitzer MJ, Tonegawa S
Neuron 2015 Sep 23;87(6):1317-1331
Neuron 2015 Sep 23;87(6):1317-1331
IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions.
Kanekura K, Ma X, Murphy JT, Zhu LJ, Diwan A, Urano F
Science signaling 2015 Jun 23;8(382):ra62
Science signaling 2015 Jun 23;8(382):ra62
Distinct speed dependence of entorhinal island and ocean cells, including respective grid cells.
Sun C, Kitamura T, Yamamoto J, Martin J, Pignatelli M, Kitch LJ, Schnitzer MJ, Tonegawa S
Proceedings of the National Academy of Sciences of the United States of America 2015 Jul 28;112(30):9466-71
Proceedings of the National Academy of Sciences of the United States of America 2015 Jul 28;112(30):9466-71
ATF6β regulates the Wfs1 gene and has a cell survival role in the ER stress response in pancreatic β-cells.
Odisho T, Zhang L, Volchuk A
Experimental cell research 2015 Jan 1;330(1):111-22
Experimental cell research 2015 Jan 1;330(1):111-22
Sarco(endo)plasmic reticulum ATPase is a molecular partner of Wolfram syndrome 1 protein, which negatively regulates its expression.
Zatyka M, Da Silva Xavier G, Bellomo EA, Leadbeater W, Astuti D, Smith J, Michelangeli F, Rutter GA, Barrett TG
Human molecular genetics 2015 Feb 1;24(3):814-27
Human molecular genetics 2015 Feb 1;24(3):814-27
Synaptic Targets of Medial Septal Projections in the Hippocampus and Extrahippocampal Cortices of the Mouse.
Unal G, Joshi A, Viney TJ, Kis V, Somogyi P
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Dec 2;35(48):15812-26
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Dec 2;35(48):15812-26
Calcium efflux from the endoplasmic reticulum leads to β-cell death.
Hara T, Mahadevan J, Kanekura K, Hara M, Lu S, Urano F
Endocrinology 2014 Mar;155(3):758-68
Endocrinology 2014 Mar;155(3):758-68
Cell type-specific genetic and optogenetic tools reveal hippocampal CA2 circuits.
Kohara K, Pignatelli M, Rivest AJ, Jung HY, Kitamura T, Suh J, Frank D, Kajikawa K, Mise N, Obata Y, Wickersham IR, Tonegawa S
Nature neuroscience 2014 Feb;17(2):269-79
Nature neuroscience 2014 Feb;17(2):269-79
Island cells control temporal association memory.
Kitamura T, Pignatelli M, Suh J, Kohara K, Yoshiki A, Abe K, Tonegawa S
Science (New York, N.Y.) 2014 Feb 21;343(6173):896-901
Science (New York, N.Y.) 2014 Feb 21;343(6173):896-901
A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome.
Lu S, Kanekura K, Hara T, Mahadevan J, Spears LD, Oslowski CM, Martinez R, Yamazaki-Inoue M, Toyoda M, Neilson A, Blanner P, Brown CM, Semenkovich CF, Marshall BA, Hershey T, Umezawa A, Greer PA, Urano F
Proceedings of the National Academy of Sciences of the United States of America 2014 Dec 9;111(49):E5292-301
Proceedings of the National Academy of Sciences of the United States of America 2014 Dec 9;111(49):E5292-301
The hippocampal CA2 region is essential for social memory.
Hitti FL, Siegelbaum SA
Nature 2014 Apr 3;508(7494):88-92
Nature 2014 Apr 3;508(7494):88-92
Autosomal dominant diabetes arising from a Wolfram syndrome 1 mutation.
Bonnycastle LL, Chines PS, Hara T, Huyghe JR, Swift AJ, Heikinheimo P, Mahadevan J, Peltonen S, Huopio H, Nuutila P, Narisu N, Goldfeder RL, Stitzel ML, Lu S, Boehnke M, Urano F, Collins FS, Laakso M
Diabetes 2013 Nov;62(11):3943-50
Diabetes 2013 Nov;62(11):3943-50
Oligomerised lychee fruit-derived polyphenol attenuates cognitive impairment in senescence-accelerated mice and endoplasmic reticulum stress in neuronal cells.
Sakurai T, Kitadate K, Nishioka H, Fujii H, Ogasawara J, Kizaki T, Sato S, Fujiwara T, Akagawa K, Izawa T, Ohno H
The British journal of nutrition 2013 Nov 14;110(9):1549-58
The British journal of nutrition 2013 Nov 14;110(9):1549-58
Vacuolar-type H+-ATPase V1A subunit is a molecular partner of Wolfram syndrome 1 (WFS1) protein, which regulates its expression and stability.
Gharanei S, Zatyka M, Astuti D, Fenton J, Sik A, Nagy Z, Barrett TG
Human molecular genetics 2013 Jan 15;22(2):203-17
Human molecular genetics 2013 Jan 15;22(2):203-17
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 11558-1-AP(WFS1 antibody) at dilution of 1:1500
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 11558-1-AP(WFS1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-WFS1 (IP:11558-1-AP, 4ug; Detection:11558-1-AP 1:600) with mouse brain tissue lysate 6500ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The WFS1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human WFS1. This antibody recognizes human,mouse,rat antigen. The WFS1 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
