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- Antibody Data
- Antigen structure
- References [18]
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- Product number
- 26995-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- WFS1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated WFS1 antibody (Cat. #26995-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Astrocyte-mediated regulation of BLA(WFS1) neurons alleviates risk-assessment deficits in DISC1-N mice.
Acetylcholine synergizes with netrin-1 to drive persistent firing in the entorhinal cortex.
Mouse hippocampal CA1 VIP interneurons detect novelty in the environment and support recognition memory.
Histone methyltransferase SETD2 is required for proper hippocampal lamination and neuronal maturation.
The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes.
KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors.
Phosphoproteomics Reveals the Wolframin-Calcium Axis as an Important Pathogenic Signaling Node in Primary Aldosteronism.
A proximity labeling strategy enables proteomic analysis of inter-organelle membrane contacts.
Hippocampus shapes cortical sensory output and novelty coding through a direct feedback circuit.
Loss of Function of WFS1 Causes ER Stress-Mediated Inflammation in Pancreatic Beta-Cells.
Wolframin is a novel regulator of tau pathology and neurodegeneration.
The fasciola cinereum subregion of the hippocampus is important for the acquisition of visual contextual memory.
WFS1 protein expression correlates with clinical progression of optic atrophy in patients with Wolfram syndrome.
Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical models.
Activity disruption causes degeneration of entorhinal neurons in a mouse model of Alzheimer's circuit dysfunction.
Wolfram syndrome 1b mutation suppresses Mauthner-cell axon regeneration via ER stress signal pathway.
Wolframin-1-expressing neurons in the entorhinal cortex propagate tau to CA1 neurons and impair hippocampal memory in mice.
WFS1 functions in ER export of vesicular cargo proteins in pancreatic β-cells.
Zhou X, Xiao Q, Liu Y, Chen S, Xu X, Zhang Z, Hong Y, Shao J, Chen Y, Chen Y, Wang L, Yang F, Tu J
Neuron 2024 Jul 3;112(13):2197-2217.e7
Neuron 2024 Jul 3;112(13):2197-2217.e7
Acetylcholine synergizes with netrin-1 to drive persistent firing in the entorhinal cortex.
Glasgow SD, Fisher TAJ, Wong EW, Lançon K, Feighan KM, Beamish IV, Gibon J, Séguéla P, Ruthazer ES, Kennedy TE
Cell reports 2024 Feb 27;43(2):113812
Cell reports 2024 Feb 27;43(2):113812
Mouse hippocampal CA1 VIP interneurons detect novelty in the environment and support recognition memory.
Tamboli S, Singh S, Topolnik D, El Amine Barkat M, Radhakrishnan R, Guet-McCreight A, Topolnik L
Cell reports 2024 Apr 23;43(4):114115
Cell reports 2024 Apr 23;43(4):114115
Histone methyltransferase SETD2 is required for proper hippocampal lamination and neuronal maturation.
Hu G, Zheng Y, Zhang B, Zhao C, Xu L, Wei J, Jing J, Liu Y, Zeng T, Zhou Y
Molecular biology of the cell 2024 Apr 1;35(4):ar54
Molecular biology of the cell 2024 Apr 1;35(4):ar54
The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes.
Yang X, Wan R, Liu Z, Feng S, Yang J, Jing N, Tang K
eLife 2023 Sep 26;12
eLife 2023 Sep 26;12
KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors.
Zhang B, Zhao C, Shen W, Li W, Zheng Y, Kong X, Wang J, Wu X, Zeng T, Liu Y, Zhou Y
Nature communications 2023 Oct 14;14(1):6489
Nature communications 2023 Oct 14;14(1):6489
Phosphoproteomics Reveals the Wolframin-Calcium Axis as an Important Pathogenic Signaling Node in Primary Aldosteronism.
Ma L, Yang S, Yang Y, Chen X, Yang J, He Y, Cheng Q, Li J, Kang B, Tang S, Zhang A, Shu X, Li X, Shen H, Jing Y, Song Y, Li Q, Hu J
Hypertension (Dallas, Tex. : 1979) 2023 May;80(5):995-1010
Hypertension (Dallas, Tex. : 1979) 2023 May;80(5):995-1010
A proximity labeling strategy enables proteomic analysis of inter-organelle membrane contacts.
Zhou M, Kong B, Zhang X, Xiao K, Lu J, Li W, Li M, Li Z, Ji W, Hou J, Xu T
iScience 2023 Jul 21;26(7):107159
iScience 2023 Jul 21;26(7):107159
Hippocampus shapes cortical sensory output and novelty coding through a direct feedback circuit.
Butola T, Hernández Frausto M, Blankvoort S, Flatset MS, Peng L, Elmaleh M, Hairston A, Hussain F, Clopath C, Kentros C, Basu J
Research square 2023 Aug 23;
Research square 2023 Aug 23;
Loss of Function of WFS1 Causes ER Stress-Mediated Inflammation in Pancreatic Beta-Cells.
Morikawa S, Blacher L, Onwumere C, Urano F
Frontiers in endocrinology 2022;13:849204
Frontiers in endocrinology 2022;13:849204
Wolframin is a novel regulator of tau pathology and neurodegeneration.
Chen S, Acosta D, Li L, Liang J, Chang Y, Wang C, Fitzgerald J, Morrison C, Goulbourne CN, Nakano Y, Villegas NCH, Venkataraman L, Brown C, Serrano GE, Bell E, Wemlinger T, Wu M, Kokiko-Cochran ON, Popovich P, Flowers XE, Honig LS, Vonsattel JP, Scharre DW, Beach TG, Ma Q, Kuret J, Kõks S, Urano F, Duff KE, Fu H
Acta neuropathologica 2022 May;143(5):547-569
Acta neuropathologica 2022 May;143(5):547-569
The fasciola cinereum subregion of the hippocampus is important for the acquisition of visual contextual memory.
Park SB, Lim HY, Lee EY, Yoo SW, Jung HS, Lee E, Sun W, Lee I
Progress in neurobiology 2022 Mar;210:102217
Progress in neurobiology 2022 Mar;210:102217
WFS1 protein expression correlates with clinical progression of optic atrophy in patients with Wolfram syndrome.
Hu K, Zatyka M, Astuti D, Beer N, Dias RP, Kulkarni A, Ainsworth J, Wright B, Majander A, Yu-Wai-Man P, Williams D, Barrett T
Journal of medical genetics 2022 Jan;59(1):65-74
Journal of medical genetics 2022 Jan;59(1):65-74
Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical models.
Crouzier L, Danese A, Yasui Y, Richard EM, Liévens JC, Patergnani S, Couly S, Diez C, Denus M, Cubedo N, Rossel M, Thiry M, Su TP, Pinton P, Maurice T, Delprat B
Science translational medicine 2022 Feb 9;14(631):eabh3763
Science translational medicine 2022 Feb 9;14(631):eabh3763
Activity disruption causes degeneration of entorhinal neurons in a mouse model of Alzheimer's circuit dysfunction.
Zhao R, Grunke SD, Wood CA, Perez GA, Comstock M, Li MH, Singh AK, Park KW, Jankowsky JL
eLife 2022 Dec 5;11
eLife 2022 Dec 5;11
Wolfram syndrome 1b mutation suppresses Mauthner-cell axon regeneration via ER stress signal pathway.
Wang Z, Wang X, Shi L, Cai Y, Hu B
Acta neuropathologica communications 2022 Dec 17;10(1):184
Acta neuropathologica communications 2022 Dec 17;10(1):184
Wolframin-1-expressing neurons in the entorhinal cortex propagate tau to CA1 neurons and impair hippocampal memory in mice.
Delpech JC, Pathak D, Varghese M, Kalavai SV, Hays EC, Hof PR, Johnson WE, Ikezu S, Medalla M, Luebke JI, Ikezu T
Science translational medicine 2021 Sep 15;13(611):eabe8455
Science translational medicine 2021 Sep 15;13(611):eabe8455
WFS1 functions in ER export of vesicular cargo proteins in pancreatic β-cells.
Wang L, Liu H, Zhang X, Song E, Wang Y, Xu T, Li Z
Nature communications 2021 Nov 30;12(1):6996
Nature communications 2021 Nov 30;12(1):6996
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