abx001429

antibody from Abbexa

Targeting: WFS1 DFNA14, DFNA38, DFNA6, DIDMOAD, WFS

Western blot (Recommended by provider)

Antibody Data

Product number

abx001429

Provider

Abbexa

Product name

Wolframin (WFS1) Antibody

Antibody type

Polyclonal

Description

WFS1 Antibody is a Rabbit Polyclonal antibody against WFS1. This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

> 1 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.