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- Antigen structure
- References [10]
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- Product number
- 16616-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16616-1-AP, RRID:AB_2133350
- Product name
- LAG-3 antibody
- Antibody type
- Polyclonal
- Description
- LAG-3 antibody (Cat. #16616-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Implications of LAG3 and CTLA4 immune checkpoints beyond PD-1/PD-L1 as a potential target in determining the prognosis of uveal melanoma patients.
The Identification of Gamma-Glutamyl Hydrolase in Uterine Corpus Endometrial Carcinoma: a Predictive Model and Machine Learning.
Blockade of PD-1 and LAG-3 expression on CD8+ T cells promotes the tumoricidal effects of CD8+ T cells.
Effects of Nanosecond Pulsed Electric Field on Immune Checkpoint Receptors in Melanoma Cells.
Targeting fibrinogen-like protein 1 enhances immunotherapy in hepatocellular carcinoma.
Effect of DPP4/CD26 expression on SARS‑CoV‑2 susceptibility, immune response, adenosine (derivatives m(6)(2)A and CD) regulations on patients with cancer and healthy individuals.
CD4(+)LAG3(+)T cells are decreased in SSc-ILD and affect fibroblast mesenchymal transition by TGF-β3.
The immune checkpoint expression in the tumor immune microenvironment of DLBCL: Clinicopathologic features and prognosis.
Novel roles of VAT1 expression in the immunosuppressive action of diffuse gliomas.
Single-cell RNA-seq reveals transcriptional landscape and intratumor heterogenicity in gallbladder cancer liver metastasis microenvironment.
Kashyap S, Singh MK, Kumar N, Jha J, Lomi N, Meel R, Bakhshi S, Sen S, Singh L
The British journal of ophthalmology 2024 May 21;108(6):903-912
The British journal of ophthalmology 2024 May 21;108(6):903-912
The Identification of Gamma-Glutamyl Hydrolase in Uterine Corpus Endometrial Carcinoma: a Predictive Model and Machine Learning.
Zhu C, Du Y, Huai Q, Fang N, Xu W, Yang J, Li X, Zhang Y, Zhang X, Dai H, Li X, Wang H, Dai Y
Reproductive sciences (Thousand Oaks, Calif.) 2024 Feb;31(2):532-549
Reproductive sciences (Thousand Oaks, Calif.) 2024 Feb;31(2):532-549
Blockade of PD-1 and LAG-3 expression on CD8+ T cells promotes the tumoricidal effects of CD8+ T cells.
Ma J, Yan S, Zhao Y, Yan H, Zhang Q, Li X
Frontiers in immunology 2023;14:1265255
Frontiers in immunology 2023;14:1265255
Effects of Nanosecond Pulsed Electric Field on Immune Checkpoint Receptors in Melanoma Cells.
Sauer N, Szlasa W, Szewczyk A, Novickij V, Saczko J, Baczyńska D, Daczewska M, Kulbacka J
Pharmaceuticals (Basel, Switzerland) 2023 Sep 27;16(10)
Pharmaceuticals (Basel, Switzerland) 2023 Sep 27;16(10)
Targeting fibrinogen-like protein 1 enhances immunotherapy in hepatocellular carcinoma.
Lin M, He J, Zhang X, Sun X, Dong W, Zhang R, Xu Y, Lv L
The Journal of clinical investigation 2023 May 1;133(9)
The Journal of clinical investigation 2023 May 1;133(9)
Effect of DPP4/CD26 expression on SARS‑CoV‑2 susceptibility, immune response, adenosine (derivatives m(6)(2)A and CD) regulations on patients with cancer and healthy individuals.
Du J, Fu J, Zhang W, Zhang L, Chen H, Cheng J, He T, Fu J
International journal of oncology 2023 Mar;62(3)
International journal of oncology 2023 Mar;62(3)
CD4(+)LAG3(+)T cells are decreased in SSc-ILD and affect fibroblast mesenchymal transition by TGF-β3.
Qin L, Lin H, Zhu F, Wang J, Feng T, Xu T, Zhang G, Zhang X
iScience 2023 Dec 15;26(12):108225
iScience 2023 Dec 15;26(12):108225
The immune checkpoint expression in the tumor immune microenvironment of DLBCL: Clinicopathologic features and prognosis.
Ma J, Pang X, Li J, Zhang W, Cui W
Frontiers in oncology 2022;12:1069378
Frontiers in oncology 2022;12:1069378
Novel roles of VAT1 expression in the immunosuppressive action of diffuse gliomas.
Yang P, Wang K, Zhang C, Wang Z, Liu Q, Wang J, Jiang T, Shan X
Cancer immunology, immunotherapy : CII 2021 Sep;70(9):2589-2600
Cancer immunology, immunotherapy : CII 2021 Sep;70(9):2589-2600
Single-cell RNA-seq reveals transcriptional landscape and intratumor heterogenicity in gallbladder cancer liver metastasis microenvironment.
Zhang Y, You WH, Li X, Wang P, Sha B, Liang Y, Qiu J, Zhou J, Hu H, Lu L
Annals of translational medicine 2021 May;9(10):889
Annals of translational medicine 2021 May;9(10):889
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- The LAG-3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human LAG-3. This antibody recognizes human,mouse,rat antigen. The LAG-3 antibody has been validated for the following applications: ELISA, WB analysis.
