Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Flow cytometry [2]
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Validation data
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- Product number
- FAB23193A - Provider product page
- Provider
- R&D Systems
- Product name
- Human LAG-3 APC-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human LAG-3 in direct ELISAs.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Antigen sequence
P18627
- Isotype
- IgG
- Antibody clone number
- 874501
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Diagnostic value of peripheral blood immune profiling in colorectal cancer.
Enhancing the Potency and Specificity of Engineered T Cells for Cancer Treatment.
Choi J, Maeng HG, Lee SJ, Kim YJ, Kim DW, Lee HN, Namgung JH, Oh HM, Kim TJ, Jeong JE, Park SJ, Choi YM, Kang YW, Yoon SG, Lee JK
Annals of surgical treatment and research 2018 Jun;94(6):312-321
Annals of surgical treatment and research 2018 Jun;94(6):312-321
Enhancing the Potency and Specificity of Engineered T Cells for Cancer Treatment.
Sukumaran S, Watanabe N, Bajgain P, Raja K, Mohammed S, Fisher WE, Brenner MK, Leen AM, Vera JF
Cancer discovery 2018 Aug;8(8):972-987
Cancer discovery 2018 Aug;8(8):972-987
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of LAG-3 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with 1 μg/mL PHA for 5 days were stained with Mouse Anti-Human LAG-3 APC-conjugated Monoclonal Antibody (Catalog # FAB23193A) and Mouse Anti-Human CD3 epsilon PE-conjugated Monoclonal Antibody (Catalog # FAB100P). Quadrant markers were set based on control antibody staining (Catalog # IC002A). View our protocol for Staining Membrane-associated Proteins.
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of LAG-3 in HEK293 Human Cell Line Transfected with Human LAG-3 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) human LAG-3 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human LAG-3 APC-conjugated Monoclonal Antibody (Catalog # FAB23193A). Quadrant markers were set based on control antibody staining (Catalog # IC002A, data not shown). View our protocol for Staining Membrane-associated Proteins.