Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10880-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10880-1-AP, RRID:AB_2109304
- Product name
- GAMT antibody
- Antibody type
- Polyclonal
- Description
- GAMT antibody (Cat. #10880-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, zebrafish and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Zebrafish
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Gliomas phenocopy an inborn error of metabolism to drive neuronal activity and tumor growth.
Creatine mitigates neurogenesis impairment caused by defective DcpS decapping.
GAMT facilitates tumor progression via inhibiting p53 in clear cell renal cell carcinoma.
Spatial metabolomics highlights metabolic reprogramming in acute myeloid leukemia mice through creatine pathway.
Investigation of ferroptosis-associated molecular subtypes and immunological characteristics in lupus nephritis based on artificial neural network learning.
Myeloid cell-derived creatine in the hypoxic niche promotes glioblastoma growth.
Unbalanced redox status network as an early pathological event in congenital cataracts.
Transcriptomics combined with metabolomics analysis of the mechanism of agmatine in the treatment of septic liver injury.
Cytochalasin Q exerts anti-melanoma effect by inhibiting creatine kinase B.
GATM and GAMT synthesize creatine locally throughout the mammalian body and within oligodendrocytes of the brain.
Artepillin C, a Key Component of Brazilian Propolis, Induces Thermogenesis in Inguinal White Adipose Tissue of Mice through a Creatine-Metabolism-Related Thermogenic Pathway.
Expression patterns of the creatine metabolism-related molecules AGAT, GAMT and CT1 in adult zebrafish Danio rerio.
Abdullah KG, Miki K, Edgar CK, Wu SA, Xiao Y, Savani MR, Ghoche MT, Kotermanski SE, Huang YT, Traylor JI, Guo L, Gunn K, Hicks WH, Shi DD, Tang M, Levitt MM, El-Shami M, Oken S, Manoj N, Smith BC, Puliyappadamba VT, Kaphle P, Shipman T, West RE, Liang C, Patel TR, Hatanpaa KJ, Raj P, Ma S, Ksendzovsky A, Nolin TD, Lega BC, Zinn PO, Kuhn BJ, Clark NM, Williams C, Mani DR, Gillette MA, Calzado MA, Xu L, Zacharias LG, Cai F, Mathews TP, Losman JA, Richardson TE, Levi B, Monje M, Gibson JR, Khan OH, Agnihotri S, Huber KM, Chamberland S, DeBerardinis RJ, McBrayer SK
bioRxiv : the preprint server for biology 2025 Sep 18;
bioRxiv : the preprint server for biology 2025 Sep 18;
Creatine mitigates neurogenesis impairment caused by defective DcpS decapping.
Yang J, Palsule G, Jiao X, Messenger JS, Hart RP, Kiledjian M
Scientific reports 2025 May 23;15(1):17915
Scientific reports 2025 May 23;15(1):17915
GAMT facilitates tumor progression via inhibiting p53 in clear cell renal cell carcinoma.
Zheng B, Liu K, Feng J, Ouyang Q, Jia T, Wang Y, Tian S, Chen X, Cai T, Wen L, Zhang X, Li X, Ma X
Biology direct 2025 Apr 2;20(1):43
Biology direct 2025 Apr 2;20(1):43
Spatial metabolomics highlights metabolic reprogramming in acute myeloid leukemia mice through creatine pathway.
Bao Y, Qiao J, Gong W, Zhang R, Zhou Y, Xie Y, Xie Y, He J, Yin T
Acta pharmaceutica Sinica. B 2024 Oct;14(10):4461-4477
Acta pharmaceutica Sinica. B 2024 Oct;14(10):4461-4477
Investigation of ferroptosis-associated molecular subtypes and immunological characteristics in lupus nephritis based on artificial neural network learning.
Zhang L, Yan Q, Lin M, He J, Tian J, Chen Z, Hong F
Arthritis research & therapy 2024 Jul 3;26(1):126
Arthritis research & therapy 2024 Jul 3;26(1):126
Myeloid cell-derived creatine in the hypoxic niche promotes glioblastoma growth.
Rashidi A, Billingham LK, Zolp A, Chia TY, Silvers C, Katz JL, Park CH, Delay S, Boland L, Geng Y, Markwell SM, Dmello C, Arrieta VA, Zilinger K, Jacob IM, Lopez-Rosas A, Hou D, Castro B, Steffens AM, McCortney K, Walshon JP, Flowers MS, Lin H, Wang H, Zhao J, Sonabend A, Zhang P, Ahmed AU, Brat DJ, Heiland DH, Lee-Chang C, Lesniak MS, Chandel NS, Miska J
Cell metabolism 2024 Jan 2;36(1):62-77.e8
Cell metabolism 2024 Jan 2;36(1):62-77.e8
Unbalanced redox status network as an early pathological event in congenital cataracts.
Bejarano E, Whitcomb EA, Pfeiffer RL, Rose KL, Asensio MJ, RodrÃguez-Navarro JA, Ponce-Mora A, Canto A, Almansa I, Schey KL, Jones BW, Taylor A, Rowan S
Redox biology 2023 Oct;66:102869
Redox biology 2023 Oct;66:102869
Transcriptomics combined with metabolomics analysis of the mechanism of agmatine in the treatment of septic liver injury.
Huang L, Gan L, Pan J, Zhong L, Wang Q, Luo S, Tian J, Liang H
Annals of translational medicine 2022 May;10(10):578
Annals of translational medicine 2022 May;10(10):578
Cytochalasin Q exerts anti-melanoma effect by inhibiting creatine kinase B.
Lu Y, Zhang P, Chen H, Tong Q, Wang J, Li Q, Tian C, Yang J, Li S, Zhang Z, Yuan H, Xiang M
Toxicology and applied pharmacology 2022 Apr 15;441:115971
Toxicology and applied pharmacology 2022 Apr 15;441:115971
GATM and GAMT synthesize creatine locally throughout the mammalian body and within oligodendrocytes of the brain.
Baker SA, Gajera CR, Wawro AM, Corces MR, Montine TJ
Brain research 2021 Nov 1;1770:147627
Brain research 2021 Nov 1;1770:147627
Artepillin C, a Key Component of Brazilian Propolis, Induces Thermogenesis in Inguinal White Adipose Tissue of Mice through a Creatine-Metabolism-Related Thermogenic Pathway.
Nishikawa S, Hydo T, Aoyama H, Miyata R, Kumazawa S, Tsuda T
Journal of agricultural and food chemistry 2020 Jan 29;68(4):1007-1014
Journal of agricultural and food chemistry 2020 Jan 29;68(4):1007-1014
Expression patterns of the creatine metabolism-related molecules AGAT, GAMT and CT1 in adult zebrafish Danio rerio.
Wang L, Chen D, Yang L, Huang S, Zhang Y, Zhang H
Journal of fish biology 2010 Apr;76(5):1212-9
Journal of fish biology 2010 Apr;76(5):1212-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 10880-1-AP(GAMT antibody) at dilution of 1:6000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The GAMT antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GAMT. This antibody recognizes human, mouse, rat, zebrafish antigen. The GAMT antibody has been validated for the following applications: ELISA, WB, IHC analysis.