20989-1-AP

antibody from Proteintech Group

Targeting: PDX1 IDX-1, IPF1, MODY4, PDX-1, STF-1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

20989-1-AP

Provider

Proteintech Group

Product name

PDX1 antibody

Antibody type

Polyclonal

Description

PDX1 antibody (Cat. #20989-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB,ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Generation of a human induced pluripotent stem cell line overexpressing CCL22 with islet cells differentiation potential.

Jinliang D, Fang B, Xiaofeng Z, Xiaoshun H, Anbin H
Stem cell research 2024 Mar;75:103302

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Glutathione Induces Keap1 S-Glutathionylation and Mitigates Oscillating Glucose-Induced β-Cell Dysfunction by Activating Nrf2.

Chen X, Zhou Q, Chen H, Bai J, An R, Zhang K, Zhang X, An H, Zhang J, Wang Y, Li M
Antioxidants (Basel, Switzerland) 2024 Mar 27;13(4)

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Angiotensin (1-7) reverses glucose-induced islet β cell dedifferentiation by Wnt/β-catenin/FoxO1 signalling pathway.

Guo D, He J, Guo H, Song G, Peng L, An M, Wang C
Endokrynologia Polska 2023;74(5):544-552

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Human umbilical cord-derived mesenchymal stem cells alleviate oxidative stress-induced islet impairment via the Nrf2/HO-1 axis.

Liu P, Cao B, Zhou Y, Zhang H, Wang C
Journal of molecular cell biology 2023 Nov 27;15(5)

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Lycopene ameliorates islet function and down-regulates the TLR4/MyD88/NF-κB pathway in diabetic mice and Min6 cells.

Liu Y, Tian Y, Dai X, Liu T, Zhang Y, Wang S, Shi H, Yin J, Xu T, Zhu R, Zhang Y, Zhao D, Gao S, Wang XD, Wang L, Zhang D
Food & function 2023 Jun 6;14(11):5090-5104

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Dual-core coaxial bioprinting of double-channel constructs with a potential for perfusion and interaction of cells.

Yu Y, Xie R, He Y, Zhao F, Zhang Q, Wang W, Zhang Y, Hu J, Luo D, Peng W
Biofabrication 2022 May 26;14(3)

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Targeted Polymeric Nanoparticles Based on Mangiferin for Enhanced Protection of Pancreatic β-Cells and Type 1 Diabetes Mellitus Efficacy.

Wang M, Zhang Z, Huo Q, Wang M, Sun Y, Liu H, Chang J, He B, Liang Y
ACS applied materials & interfaces 2022 Mar 9;14(9):11092-11103

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SARS-CoV-2 in the pancreas and the impaired islet function in COVID-19 patients.

Ji N, Zhang M, Ren L, Wang Y, Hu B, Xiang J, Gong Y, Wu C, Qu G, Ding W, Yin Z, Li S, Wang Z, Zhou L, Chen X, Ma Y, Tang J, Liu Y, Liu L, Huang M
Emerging microbes & infections 2022 Dec;11(1):1115-1125

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Three-dimensional cell-culture platform based on hydrogel with tunable microenvironmental properties to improve insulin-secreting function of MIN6 cells.

Zhang M, Yan S, Xu X, Yu T, Guo Z, Ma M, Zhang Y, Gu Z, Feng Y, Du C, Wan M, Hu K, Han X, Gu N
Biomaterials 2021 Mar;270:120687

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Tectorigenin enhances PDX1 expression and protects pancreatic β-cells by activating ERK and reducing ER stress.

Yao X, Li K, Liang C, Zhou Z, Wang J, Wang S, Liu L, Yu CL, Song ZB, Bao YL, Zheng LH, Sun Y, Wang G, Huang Y, Yi J, Sun L, Li Y
The Journal of biological chemistry 2020 Sep 11;295(37):12975-12992

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Screening active components from Rubus amabilis for pancreatic β-cells protection.

Sun M, Zhu T, Tong J, Caidan R, Wang K, Kai G, Zhang W, Ru L, Pengcuo J, Tong L
Pharmaceutical biology 2020 Dec;58(1):674-685

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Effects of Neuropeptide Substance P on Proliferation and β-Cell Differentiation of Adult Pancreatic Ductal Cells.

Zhang N, Gao D, Liu Y, Ji S, Sha L
Frontiers in neuroscience 2018;12:806

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The Synergy of Two Factors on Insulin Expression.

Luo Y, Xu Y, Wang ZY, Li X, Xing WB, Zhang TC
Cellular reprogramming 2018 Feb;20(1):49-54

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Hepatitis B X-interacting protein promotes the formation of the insulin gene-transcribing protein complex Pdx-1/Neurod1 in animal pancreatic β-cells.

Li H, Wang Z, Li Y, Fang R, Wang H, Shi H, Zhang X, Zhang W, Ye L
The Journal of biological chemistry 2018 Feb 9;293(6):2053-2065