ABIN967683

antibody from antibodies-online

Targeting: PDX1 IDX-1, IPF1, MODY4, PDX-1, STF-1

Western blot (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

ABIN967683

Provider

antibodies-online

Product name

anti-Pancreatic and Duodenal Homeobox 1 (PDX1) antibody

Antibody type

Monoclonal

Antigen

Human PDX-1 Recombinant Protein

Description

Purified from tissue culture supernatant or ascites by affinity chromatography.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

658A5

Vial size

0.1 mg

Concentration

0.5 mg/ml

Storage

4°C

References

Submitted references

pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis.

Gannon M, Ables ET, Crawford L, Lowe D, Offield MF, Magnuson MA, Wright CV
Developmental biology 2008 Feb 15;314(2):406-17

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A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis.

Babu DA, Deering TG, Mirmira RG
Molecular genetics and metabolism 2007 Sep-Oct;92(1-2):43-55

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Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells.

D'Amour KA, Bang AG, Eliazer S, Kelly OG, Agulnick AD, Smart NG, Moorman MA, Kroon E, Carpenter MK, Baetge EE
Nature biotechnology 2006 Nov;24(11):1392-401

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Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors.

Gu G, Dubauskaite J, Melton DA
Development (Cambridge, England) 2002 May;129(10):2447-57

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IPF1, a homeodomain-containing transactivator of the insulin gene.

Ohlsson H, Karlsson K, Edlund T
The EMBO journal 1993 Nov;12(11):4251-9