Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN967683 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Pancreatic and Duodenal Homeobox 1 (PDX1) antibody
- Antibody type
- Monoclonal
- Antigen
- Human PDX-1 Recombinant Protein
- Description
- Purified from tissue culture supernatant or ascites by affinity chromatography.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 658A5
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- 4°C
Submitted references pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis.
A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis.
Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells.
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors.
IPF1, a homeodomain-containing transactivator of the insulin gene.
Gannon M, Ables ET, Crawford L, Lowe D, Offield MF, Magnuson MA, Wright CV
Developmental biology 2008 Feb 15;314(2):406-17
Developmental biology 2008 Feb 15;314(2):406-17
A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis.
Babu DA, Deering TG, Mirmira RG
Molecular genetics and metabolism 2007 Sep-Oct;92(1-2):43-55
Molecular genetics and metabolism 2007 Sep-Oct;92(1-2):43-55
Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells.
D'Amour KA, Bang AG, Eliazer S, Kelly OG, Agulnick AD, Smart NG, Moorman MA, Kroon E, Carpenter MK, Baetge EE
Nature biotechnology 2006 Nov;24(11):1392-401
Nature biotechnology 2006 Nov;24(11):1392-401
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors.
Gu G, Dubauskaite J, Melton DA
Development (Cambridge, England) 2002 May;129(10):2447-57
Development (Cambridge, England) 2002 May;129(10):2447-57
IPF1, a homeodomain-containing transactivator of the insulin gene.
Ohlsson H, Karlsson K, Edlund T
The EMBO journal 1993 Nov;12(11):4251-9
The EMBO journal 1993 Nov;12(11):4251-9
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