BS8409

antibody from Bioworld Technology, Inc
Targeting: SPTLC1 hLCB1, HSAN1, HSN1, LCB1, SPTI
Provider product page for BS8409
Western blot
Immunohistochemistry

Antibody data

Product number
BS8409 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SPTLC1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human SPTLC1.
Description
SPTLC1 (serine palmitoyltransferase 1), also known as LCB1, and SPTLC2 (serine palmitoyltransferase 2), also known as LCB2, together catalyze sphingolipid biosynthesis by converting L-serine and palmitoyl-CoA to 3-oxosphinganine, utilizing pyridoxal 5'-phosphate as a cofactor. Increases in transepidermal water loss triggers upregulation of serine palmitoyltransferase mRNA expression in humans. Deficiencies in wild type SPTLC1 and SPTLC2 can lead to hereditary sensory neuropathy, atopic eczema, and psoriasis.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SPTLC1 protein structure - BS8409 shown in red.