Antibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 15484-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15484-1-AP, RRID:AB_2094400
- Product name
- DNAJB11 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DNAJB11 antibody (Cat. #15484-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Quantitative Measurement of Transthyretin Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Dnajb11-Kidney Disease Develops from Reduced Polycystin-1 Dosage but not Unfolded Protein Response in Mice.
UFMylation of HRD1 regulates endoplasmic reticulum homeostasis.
Quantitative Measurement of Secretory Protein Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Exosomal DNAJB11 promotes the development of pancreatic cancer by modulating the EGFR/MAPK pathway.
Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling.
The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase.
Role of IRE1α in podocyte proteostasis and mitochondrial health.
Urinary ERdj3 and mesencephalic astrocyte-derived neutrophic factor identify endoplasmic reticulum stress in glomerular disease.
Differentiation Drives Widespread Rewiring of the Neural Stem Cell Chaperone Network.
Curcumin modulates the apolipoprotein B mRNA editing by coordinating the expression of cytidine deamination to uridine editosome components in primary mouse hepatocytes.
Quantitative Interactome Proteomics Reveals a Molecular Basis for ATF6-Dependent Regulation of a Destabilized Amyloidogenic Protein.
PERK Signaling Regulates Extracellular Proteostasis of an Amyloidogenic Protein During Endoplasmic Reticulum Stress.
Modulation of calreticulin expression reveals a novel exosome-mediated mechanism of Z variant α(1)-antitrypsin disposal.
Long Interleukin-22 Binding Protein Isoform-1 Is an Intracellular Activator of the Unfolded Protein Response.
Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II.
Erdj3 Has an Essential Role for Z Variant Alpha-1-Antitrypsin Degradation.
Defining Hsp70 Subnetworks in Dengue Virus Replication Reveals Key Vulnerability in Flavivirus Infection.
Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis.
A high-throughput cell-based Gaussia luciferase reporter assay for identifying modulators of fibulin-3 secretion.
Lyu Z, Genereux JC
Frontiers in chemical biology 2023;2
Frontiers in chemical biology 2023;2
Dnajb11-Kidney Disease Develops from Reduced Polycystin-1 Dosage but not Unfolded Protein Response in Mice.
Ghosh Roy S, Li Z, Guo Z, Long KT, Rehrl S, Tian X, Dong K, Besse W
Journal of the American Society of Nephrology : JASN 2023 Sep 1;34(9):1521-1534
Journal of the American Society of Nephrology : JASN 2023 Sep 1;34(9):1521-1534
UFMylation of HRD1 regulates endoplasmic reticulum homeostasis.
Luo H, Jiao QB, Shen CB, Gong WY, Yuan JH, Liu YY, Chen Z, Liu J, Xu XL, Cong YS, Zhang XW
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23221
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23221
Quantitative Measurement of Secretory Protein Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Lyu Z, Genereux JC
bioRxiv : the preprint server for biology 2023 Jul 20;
bioRxiv : the preprint server for biology 2023 Jul 20;
Exosomal DNAJB11 promotes the development of pancreatic cancer by modulating the EGFR/MAPK pathway.
Liu P, Zu F, Chen H, Yin X, Tan X
Cellular & molecular biology letters 2022 Oct 8;27(1):87
Cellular & molecular biology letters 2022 Oct 8;27(1):87
Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling.
Lyu Z, Sycks MM, Espinoza MF, Nguyen KK, Montoya MR, Galapate CM, Mei L, Genereux JC
ACS chemical biology 2022 Jul 15;17(7):1963-1977
ACS chemical biology 2022 Jul 15;17(7):1963-1977
The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase.
McKenna MJ, Sim SI, Ordureau A, Wei L, Harper JW, Shao S, Park E
Science (New York, N.Y.) 2020 Sep 25;369(6511)
Science (New York, N.Y.) 2020 Sep 25;369(6511)
Role of IRE1α in podocyte proteostasis and mitochondrial health.
Navarro-Betancourt JR, Papillon J, Guillemette J, Iwawaki T, Chung CF, Cybulsky AV
Cell death discovery 2020 Nov 19;6(1):128
Cell death discovery 2020 Nov 19;6(1):128
Urinary ERdj3 and mesencephalic astrocyte-derived neutrophic factor identify endoplasmic reticulum stress in glomerular disease.
Tousson-Abouelazm N, Papillon J, Guillemette J, Cybulsky AV
Laboratory investigation; a journal of technical methods and pathology 2020 Jul;100(7):945-958
Laboratory investigation; a journal of technical methods and pathology 2020 Jul;100(7):945-958
Differentiation Drives Widespread Rewiring of the Neural Stem Cell Chaperone Network.
Vonk WIM, Rainbolt TK, Dolan PT, Webb AE, Brunet A, Frydman J
Molecular cell 2020 Apr 16;78(2):329-345.e9
Molecular cell 2020 Apr 16;78(2):329-345.e9
Curcumin modulates the apolipoprotein B mRNA editing by coordinating the expression of cytidine deamination to uridine editosome components in primary mouse hepatocytes.
He P, Tian N
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2019 May;23(3):181-189
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2019 May;23(3):181-189
Quantitative Interactome Proteomics Reveals a Molecular Basis for ATF6-Dependent Regulation of a Destabilized Amyloidogenic Protein.
Plate L, Rius B, Nguyen B, Genereux JC, Kelly JW, Wiseman RL
Cell chemical biology 2019 Jul 18;26(7):913-925.e4
Cell chemical biology 2019 Jul 18;26(7):913-925.e4
PERK Signaling Regulates Extracellular Proteostasis of an Amyloidogenic Protein During Endoplasmic Reticulum Stress.
Romine IC, Wiseman RL
Scientific reports 2019 Jan 23;9(1):410
Scientific reports 2019 Jan 23;9(1):410
Modulation of calreticulin expression reveals a novel exosome-mediated mechanism of Z variant α(1)-antitrypsin disposal.
Khodayari N, Oshins R, Alli AA, Tuna KM, Holliday LS, Krotova K, Brantly M
The Journal of biological chemistry 2019 Apr 19;294(16):6240-6252
The Journal of biological chemistry 2019 Apr 19;294(16):6240-6252
Long Interleukin-22 Binding Protein Isoform-1 Is an Intracellular Activator of the Unfolded Protein Response.
Gómez-Fernández P, Urtasun A, Paton AW, Paton JC, Borrego F, Dersh D, Argon Y, Alloza I, Vandenbroeck K
Frontiers in immunology 2018;9:2934
Frontiers in immunology 2018;9:2934
Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II.
Osaki Y, Saito A, Kanemoto S, Kaneko M, Matsuhisa K, Asada R, Masaki T, Orii K, Fukao T, Tomatsu S, Imaizumi K
Cell death & disease 2018 Jul 24;9(8):808
Cell death & disease 2018 Jul 24;9(8):808
Erdj3 Has an Essential Role for Z Variant Alpha-1-Antitrypsin Degradation.
Khodayari N, Marek G, Lu Y, Krotova K, Wang RL, Brantly M
Journal of cellular biochemistry 2017 Oct;118(10):3090-3101
Journal of cellular biochemistry 2017 Oct;118(10):3090-3101
Defining Hsp70 Subnetworks in Dengue Virus Replication Reveals Key Vulnerability in Flavivirus Infection.
Taguwa S, Maringer K, Li X, Bernal-Rubio D, Rauch JN, Gestwicki JE, Andino R, Fernandez-Sesma A, Frydman J
Cell 2015 Nov 19;163(5):1108-1123
Cell 2015 Nov 19;163(5):1108-1123
Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis.
Genereux JC, Qu S, Zhou M, Ryno LM, Wang S, Shoulders MD, Kaufman RJ, Lasmézas CI, Kelly JW, Wiseman RL
The EMBO journal 2015 Jan 2;34(1):4-19
The EMBO journal 2015 Jan 2;34(1):4-19
A high-throughput cell-based Gaussia luciferase reporter assay for identifying modulators of fibulin-3 secretion.
Hulleman JD, Brown SJ, Rosen H, Kelly JW
Journal of biomolecular screening 2013 Jul;18(6):647-58
Journal of biomolecular screening 2013 Jul;18(6):647-58
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 15484-1-AP(DNAJB11 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using DNAJB11 antibody 15484-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human ovary tumor using 15484-1-AP(DNAJB11 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human ovary tumor using 15484-1-AP(DNAJB11 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue