Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 16424-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16424-1-AP, RRID:AB_2079500
- Product name
- CHMP7 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CHMP7 antibody (Cat. #16424-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Altered nuclear envelope homeostasis is a key pathogenic event in C9ORF72-linked ALS/FTD.
Identification of CHMP7 as a promising immunobiomarker for immunotherapy and chemotherapy and impact on prognosis of colorectal cancer patients.
Cellular ESCRT components are recruited to regulate the endocytic trafficking and RNA replication compartment assembly during classical swine fever virus infection.
CDK1 controls CHMP7-dependent nuclear envelope reformation.
The ESCRT machinery counteracts Nesprin-2G-mediated mechanical forces during nuclear envelope repair.
Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation.
Repair of nuclear ruptures requires barrier-to-autointegration factor.
CC2D1B Coordinates ESCRT-III Activity during the Mitotic Reformation of the Nuclear Envelope.
Membrane Binding by CHMP7 Coordinates ESCRT-III-Dependent Nuclear Envelope Reformation.
Sirtori R, Gregoire M, Collins A, Santangelo S, Chatragadda B, Cullen R, Ratti A, Fallini C
bioRxiv : the preprint server for biology 2024 Feb 4;
bioRxiv : the preprint server for biology 2024 Feb 4;
Identification of CHMP7 as a promising immunobiomarker for immunotherapy and chemotherapy and impact on prognosis of colorectal cancer patients.
Guo Y, Wang S, Liang F, Wang M
Frontiers in cell and developmental biology 2023;11:1211843
Frontiers in cell and developmental biology 2023;11:1211843
Cellular ESCRT components are recruited to regulate the endocytic trafficking and RNA replication compartment assembly during classical swine fever virus infection.
Liu CC, Liu YY, Zhou JF, Chen X, Chen H, Hu JH, Chen J, Zhang J, Sun RC, Wei JC, Go YY, Morita E, Zhou B
PLoS pathogens 2022 Feb;18(2):e1010294
PLoS pathogens 2022 Feb;18(2):e1010294
CDK1 controls CHMP7-dependent nuclear envelope reformation.
Gatta AT, Olmos Y, Stoten CL, Chen Q, Rosenthal PB, Carlton JG
eLife 2021 Jul 21;10
eLife 2021 Jul 21;10
The ESCRT machinery counteracts Nesprin-2G-mediated mechanical forces during nuclear envelope repair.
Wallis SS, Ventimiglia LN, Otigbah E, Infante E, Cuesta-Geijo MA, Kidiyoor GR, Carbajal MA, Fleck RA, Foiani M, Garcia-Manyes S, Martin-Serrano J, Agromayor M
Developmental cell 2021 Dec 6;56(23):3192-3202.e8
Developmental cell 2021 Dec 6;56(23):3192-3202.e8
Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation.
Vietri M, Schultz SW, Bellanger A, Jones CM, Petersen LI, Raiborg C, Skarpen E, Pedurupillay CRJ, Kjos I, Kip E, Timmer R, Jain A, Collas P, Knorr RL, Grellscheid SN, Kusumaatmaja H, Brech A, Micci F, Stenmark H, Campsteijn C
Nature cell biology 2020 Jul;22(7):856-867
Nature cell biology 2020 Jul;22(7):856-867
Repair of nuclear ruptures requires barrier-to-autointegration factor.
Halfmann CT, Sears RM, Katiyar A, Busselman BW, Aman LK, Zhang Q, O'Bryan CS, Angelini TE, Lele TP, Roux KJ
The Journal of cell biology 2019 Jul 1;218(7):2136-2149
The Journal of cell biology 2019 Jul 1;218(7):2136-2149
CC2D1B Coordinates ESCRT-III Activity during the Mitotic Reformation of the Nuclear Envelope.
Ventimiglia LN, Cuesta-Geijo MA, Martinelli N, Caballe A, Macheboeuf P, Miguet N, Parnham IM, Olmos Y, Carlton JG, Weissenhorn W, Martin-Serrano J
Developmental cell 2018 Dec 3;47(5):547-563.e6
Developmental cell 2018 Dec 3;47(5):547-563.e6
Membrane Binding by CHMP7 Coordinates ESCRT-III-Dependent Nuclear Envelope Reformation.
Olmos Y, Perdrix-Rosell A, Carlton JG
Current biology : CB 2016 Oct 10;26(19):2635-2641
Current biology : CB 2016 Oct 10;26(19):2635-2641
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 16424-1-AP(CHMP7 antibody) at dilution of 1:1200
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 16424-1-AP(CHMP7 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CHMP7 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CHMP7. This antibody recognizes human, mouse, rat antigen. The CHMP7 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
