Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 24934-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ADAMTS12 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ADAMTS12 antibody (Cat. #24934-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ADAMTS12 promotes oxaliplatin chemoresistance and angiogenesis in gastric cancer through VEGF upregulation.
Epigenetic regulatory mechanism of ADAMTS12 expression in osteoarthritis.
Effects of metalloprotease ADAMTS12 on cervical cancer cell phenotype and its potential mechanism.
ADAMTS12 promotes migration and epithelial-mesenchymal transition and predicts poor prognosis for pancreatic cancer.
ADAMTS12 acts as a tumor microenvironment related cancer promoter in gastric cancer.
Neurocan is a New Substrate for the ADAMTS12 Metalloprotease: Potential Implications in Neuropathies.
Epigenetic changes in preterm birth placenta suggest a role for ADAMTS genes in spontaneous preterm birth.
Overexpression of PRDM13 inhibits glioma cells via Rho and GTP enzyme activation protein.
Cleavage of Fibulin-2 by the aggrecanases ADAMTS-4 and ADAMTS-5 contributes to the tumorigenic potential of breast cancer cells.
Jiang Y, Huang J, Huang Z, Li W, Tan R, Li T, Chen Z, Tang X, Zhao Y, Qiu J, Li C, Chen H, Yang Z
Cellular signalling 2023 Nov;111:110866
Cellular signalling 2023 Nov;111:110866
Epigenetic regulatory mechanism of ADAMTS12 expression in osteoarthritis.
Yang S, Zhou X, Jia Z, Zhang M, Yuan M, Zhou Y, Wang J, Xia D
Molecular medicine (Cambridge, Mass.) 2023 Jul 3;29(1):86
Molecular medicine (Cambridge, Mass.) 2023 Jul 3;29(1):86
Effects of metalloprotease ADAMTS12 on cervical cancer cell phenotype and its potential mechanism.
Zou R, Gu R, Tu X, Chen J, Liu S, Xue X, Li W, Zhang Y
Discover oncology 2023 Aug 29;14(1):162
Discover oncology 2023 Aug 29;14(1):162
ADAMTS12 promotes migration and epithelial-mesenchymal transition and predicts poor prognosis for pancreatic cancer.
He RZ, Zheng JH, Yao HF, Xu DP, Yang MW, Liu DJ, Sun YW, Huo YM
Hepatobiliary & pancreatic diseases international : HBPD INT 2023 Apr;22(2):169-178
Hepatobiliary & pancreatic diseases international : HBPD INT 2023 Apr;22(2):169-178
ADAMTS12 acts as a tumor microenvironment related cancer promoter in gastric cancer.
Hou Y, Xu Y, Wu D
Scientific reports 2021 May 26;11(1):10996
Scientific reports 2021 May 26;11(1):10996
Neurocan is a New Substrate for the ADAMTS12 Metalloprotease: Potential Implications in Neuropathies.
Fontanil T, Mohamedi Y, Moncada-Pazos A, Cobo T, Vega JA, Cobo JL, García-Suárez O, Cobo J, Obaya ÁJ, Cal S
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2019;52(5):1003-1016
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2019;52(5):1003-1016
Epigenetic changes in preterm birth placenta suggest a role for ADAMTS genes in spontaneous preterm birth.
Mani S, Ghosh J, Lan Y, Senapati S, Ord T, Sapienza C, Coutifaris C, Mainigi M
Human molecular genetics 2019 Jan 1;28(1):84-95
Human molecular genetics 2019 Jan 1;28(1):84-95
Overexpression of PRDM13 inhibits glioma cells via Rho and GTP enzyme activation protein.
Zhang L, Cao H, He T, Yang J, Tao H, Wang Y, Hu Q
International journal of molecular medicine 2018 Aug;42(2):966-974
International journal of molecular medicine 2018 Aug;42(2):966-974
Cleavage of Fibulin-2 by the aggrecanases ADAMTS-4 and ADAMTS-5 contributes to the tumorigenic potential of breast cancer cells.
Fontanil T, Álvarez-Teijeiro S, Villaronga MÁ, Mohamedi Y, Solares L, Moncada-Pazos A, Vega JA, García-Suárez O, Pérez-Basterrechea M, García-Pedrero JM, Obaya AJ, Cal S
Oncotarget 2017 Feb 21;8(8):13716-13729
Oncotarget 2017 Feb 21;8(8):13716-13729
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The ADAMTS12 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ADAMTS12. This antibody recognizes human, mouse antigen. The ADAMTS12 antibody has been validated for the following applications: ELISA, WB analysis.