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- References [13]
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- Product number
- 16777-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16777-1-AP, RRID:AB_10598467
- Product name
- NEDD8 antibody
- Antibody type
- Polyclonal
- Description
- NEDD8 antibody (Cat. #16777-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, monkey and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inhibiting TRIM21 Neddylation Rejuvenates Oocyte Quality in PCOS by Regulating Ubiquitination of CPT1A.
UBE2M promotes malignant phenotypes of prostate cancer through mediating NAA10 neddylation.
SIRT1 reduced DDX5 neddylation to attenuate myocardial ischemia/reperfusion injury.
The neddylation of the RNA-dependent RNA polymerase 3D of Coxsackievirus B3 promotes viral replication.
Novel extracellular vesicle release pathway facilitated by toxic superoxide dismutase 1 oligomers.
Upregulation of Cullin1 neddylation promotes glycolysis and M1 polarization of macrophage via NF-κB p65 pathway in sepsis.
Neddylation activated TRIM25 desensitizes triple-negative breast cancer to paclitaxel via TFEB-mediated autophagy.
TC2N inhibits distant metastasis and stemness of breast cancer via blocking fatty acid synthesis.
MLN4924 Suppresses head and neck squamous cell carcinoma progression by inactivating the mTOR signaling pathway via the NEDD8/CUL4/TSC2 axis.
Let-7i-5p Regulation of Cell Morphology and Migration Through Distinct Signaling Pathways in Normal and Pathogenic Urethral Fibroblasts.
Halo and Pseudohalo Gold(I)-NHC Complexes Derived from 4,5-Diarylimidazoles with Excellent In Vitro and In Vivo Anticancer Activities Against HCC.
Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus.
Identification of NUB1 as a suppressor of mutant Huntington toxicity via enhanced protein clearance.
Na X, Liu J, Tan Y, Meng L, Guo C, Zuo N, Dai W, Cong R, Zhang B, Shi W, Hu J, Liang J, Wei S, Zhao Z, Chen J, Qiao X, Li D
Research (Washington, D.C.) 2026;9:1223
Research (Washington, D.C.) 2026;9:1223
UBE2M promotes malignant phenotypes of prostate cancer through mediating NAA10 neddylation.
Wang Q, Zhang J, Lin X, Shi R, Pan C, Hu Q, Xu L, Chen Q, Xue D, Yin J, Fu Q, Huang S
Journal of translational medicine 2026 Mar 19;24(1)
Journal of translational medicine 2026 Mar 19;24(1)
SIRT1 reduced DDX5 neddylation to attenuate myocardial ischemia/reperfusion injury.
Liang Y, Huang G, Zhu X, Huang C, Liu H, Shu L
Human cell 2026 Feb 10;39(2):43
Human cell 2026 Feb 10;39(2):43
The neddylation of the RNA-dependent RNA polymerase 3D of Coxsackievirus B3 promotes viral replication.
Li S, Dong Y, Wang X, Feng D, Luan T, Wang Z, Lin L, Chen Y, Wang Y, Fei Y, Wang Y, Zhong Z, Zhao W
Journal of virology 2025 Nov 25;99(11):e0153525
Journal of virology 2025 Nov 25;99(11):e0153525
Novel extracellular vesicle release pathway facilitated by toxic superoxide dismutase 1 oligomers.
Hnath B, Dokholyan NV
bioRxiv : the preprint server for biology 2025 Apr 10;
bioRxiv : the preprint server for biology 2025 Apr 10;
Upregulation of Cullin1 neddylation promotes glycolysis and M1 polarization of macrophage via NF-κB p65 pathway in sepsis.
Qin F, Tan H, Yang Y, Xu L, Yang X
Functional & integrative genomics 2024 Oct 30;24(6):204
Functional & integrative genomics 2024 Oct 30;24(6):204
Neddylation activated TRIM25 desensitizes triple-negative breast cancer to paclitaxel via TFEB-mediated autophagy.
Zheng B, Qian F, Wang X, Wang Y, Zhou B, Fang L
Journal of experimental & clinical cancer research : CR 2024 Jun 26;43(1):177
Journal of experimental & clinical cancer research : CR 2024 Jun 26;43(1):177
TC2N inhibits distant metastasis and stemness of breast cancer via blocking fatty acid synthesis.
Hao XL, Lv YF, Li DF, Bai FH, Gong J, Pan GQ, Su LX, Wang YL, Fu WL, Liu B, Huang L, Yan D, Tan QL, Liu JY, Guo QN
Journal of translational medicine 2024 Jan 2;22(1):6
Journal of translational medicine 2024 Jan 2;22(1):6
MLN4924 Suppresses head and neck squamous cell carcinoma progression by inactivating the mTOR signaling pathway via the NEDD8/CUL4/TSC2 axis.
Jiang Y, Le F, Huang S, Chen X, Deng Z
The international journal of biochemistry & cell biology 2024 Dec;177:106696
The international journal of biochemistry & cell biology 2024 Dec;177:106696
Let-7i-5p Regulation of Cell Morphology and Migration Through Distinct Signaling Pathways in Normal and Pathogenic Urethral Fibroblasts.
Zhang K, Yang R, Chen J, Qi E, Zhou S, Wang Y, Fu Q, Chen R, Fang X
Frontiers in bioengineering and biotechnology 2020;8:428
Frontiers in bioengineering and biotechnology 2020;8:428
Halo and Pseudohalo Gold(I)-NHC Complexes Derived from 4,5-Diarylimidazoles with Excellent In Vitro and In Vivo Anticancer Activities Against HCC.
Bian M, Fan R, Jiang G, Wang Y, Lu Y, Liu W
Journal of medicinal chemistry 2020 Sep 10;63(17):9197-9211
Journal of medicinal chemistry 2020 Sep 10;63(17):9197-9211
Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus.
Bayraktar G, Yuanxiang P, Confettura AD, Gomes GM, Raza SA, Stork O, Tajima S, Suetake I, Karpova A, Yildirim F, Kreutz MR
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2020 Nov;45(12):2120-2130
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2020 Nov;45(12):2120-2130
Identification of NUB1 as a suppressor of mutant Huntington toxicity via enhanced protein clearance.
Lu B, Al-Ramahi I, Valencia A, Wang Q, Berenshteyn F, Yang H, Gallego-Flores T, Ichcho S, Lacoste A, Hild M, Difiglia M, Botas J, Palacino J
Nature neuroscience 2013 May;16(5):562-70
Nature neuroscience 2013 May;16(5):562-70
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NEDD8 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NEDD8. This antibody recognizes human, mouse, rat antigen. The NEDD8 antibody has been validated for the following applications: ELISA, WB analysis.
