abx026692

NEDD8 antibody from Abbexa
Nedd-8
No application information provided.

Antibody data

Product number
abx026692
Provider
Abbexa
Product name
Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) Antibody
Provider product page
Abbexa - abx026692
Antibody type
Polyclonal
Description
NEDD8 is a ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Isotype
IgG
Vial size
80 µl
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Provider Type Product Number
- No reagents -