abx026692
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Antibody data
- Antibody Data
- Knockdown Reagents [0]
- References [0]
- Comments [0]
- Validations [0]
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- Product number
- abx026692
- Provider
- Abbexa
- Product name
- Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) Antibody
- Provider product page
- Abbexa - abx026692
- Antibody type
- Polyclonal
- Description
- NEDD8 is a ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 80 µl
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
| Provider | Type | Product Number |
|---|---|---|
| - No reagents - | ||