abx015935

NEDD8 antibody from Abbexa
Nedd-8
Western blot
Recommended by provider
ELISA
Recommended by provider
Immunocytochemistry
Recommended by provider
Immunohistochemistry
Recommended by provider
Flow cytometry
Recommended by provider

Antibody data

Product number
abx015935
Provider
Abbexa
Product name
Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) Antibody
Provider product page
Abbexa - abx015935
Antibody type
Monoclonal
Description
Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis.Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M.Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.Tissue specificity: Highly expressed in heart, skeletal muscle, spleen, thymus, prostate, testis, ovary, colon and leukocytes.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
100 µl
Concentration
1 mg/ml
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Provider Type Product Number
- No reagents -