Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [4]
- Immunohistochemistry [4]
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Validation data
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- Product number
- NBP1-32954 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-32954, RRID:AB_2135089
- Product name
- Rabbit Polyclonal Lysyl Oxidase Homolog 2/LOXL2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references LOXL2-mediated H3K4 oxidation reduces chromatin accessibility in triple-negative breast cancer cells.
Association between lysyl oxidase and fibrotic focus in relation with inflammation in breast cancer.
Lysyl Oxidase Enhances the Deposition of Tropoelastin through the Catalysis of Tropoelastin Molecules on the Cell Surface.
Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis.
Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis.
Cebrià-Costa JP, Pascual-Reguant L, Gonzalez-Perez A, Serra-Bardenys G, Querol J, Cosín M, Verde G, Cigliano RA, Sanseverino W, Segura-Bayona S, Iturbide A, Andreu D, Nuciforo P, Bernado-Morales C, Rodilla V, Arribas J, Yelamos J, de Herreros AG, Stracker TH, Peiró S
Oncogene 2020 Jan;39(1):79-121
Oncogene 2020 Jan;39(1):79-121
Association between lysyl oxidase and fibrotic focus in relation with inflammation in breast cancer.
Jeong YJ, Park SH, Mun SH, Kwak SG, Lee SJ, Oh HK
Oncology letters 2018 Feb;15(2):2431-2440
Oncology letters 2018 Feb;15(2):2431-2440
Lysyl Oxidase Enhances the Deposition of Tropoelastin through the Catalysis of Tropoelastin Molecules on the Cell Surface.
Sato F, Seino-Sudo R, Okada M, Sakai H, Yumoto T, Wachi H
Biological & pharmaceutical bulletin 2017;40(10):1646-1653
Biological & pharmaceutical bulletin 2017;40(10):1646-1653
Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis.
Tjin G, White ES, Faiz A, Sicard D, Tschumperlin DJ, Mahar A, Kable EPW, Burgess JK
Disease models & mechanisms 2017 Nov 1;10(11):1301-1312
Disease models & mechanisms 2017 Nov 1;10(11):1301-1312
Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis.
Wong CC, Zhang H, Gilkes DM, Chen J, Wei H, Chaturvedi P, Hubbi ME, Semenza GL
Journal of molecular medicine (Berlin, Germany) 2012 Jul;90(7):803-15
Journal of molecular medicine (Berlin, Germany) 2012 Jul;90(7):803-15
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Lysyl Oxidase Homolog 2/LOXL2 Antibody [NBP1-32954] - Non-transfected (-) and transfected (+) 293T whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with LOXL2 antibody diluted at 1:5000.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Lysyl Oxidase Homolog 2/LOXL2 Antibody [NBP1-32954] - Various whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with LOXL2 antibody diluted at a dilution of 1:1000.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Lysyl Oxidase Homolog 2/LOXL2 Antibody [NBP1-32954] - Mouse tissue extract (50 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with LOXL2 antibody diluted at 1:1000.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Lysyl Oxidase Homolog 2/LOXL2 Antibody [NBP1-32954] - Various whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with LOXL2 antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Lysyl Oxidase Homolog 2/LOXL2 Antibody [NBP1-32954] - Paraffin-embedded human cervical carcinoma diluted at 1:500.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Lysyl Oxidase Homolog 2/LOXL2 Antibody [NBP1-32954] - Paraffin-embedded mouse kidney. LOXL2 antibody diluted at 1:500.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Lysyl Oxidase Homolog 2/LOXL2 Antibody [NBP1-32954] - Human ovarian carcinoma. LOXL2 antibody at 1:500. Antigen Retrieval: Trilogy(TM) (EDTA based, pH 8.0) buffer, 15 min.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Lysyl Oxidase Homolog 2/LOXL2 Antibody [NBP1-32954] - antibody detects LOXL2 protein at nucleus by immunohistochemical analysis. Sample: Paraffin-embedded human esophageal carcinoma. LOXL2 stained by LOXL2 antibody diluted at 1:3000. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min