Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 14258-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14258-1-AP, RRID:AB_2139745
- Product name
- MBD3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MBD3 antibody (Cat. #14258-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CARM1 hypermethylates the NuRD chromatin remodeling complex to promote cell cycle gene expression and breast cancer development.
MBD3 promotes epithelial-mesenchymal transition in gastric cancer cells by upregulating ACTG1 via the PI3K/AKT pathway.
Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells.
MBD3 as a Potential Biomarker for Colon Cancer: Implications for Epithelial-Mesenchymal Transition (EMT) Pathways.
Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk.
Demethylation of HACE1 gene promoter by propofol promotes autophagy of human A549 cells.
The Expression of MBD6 Is Associated with Tumor Size in Uterine Leiomyomas.
Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development.
Chen X, Huang MF, Fan DM, He YH, Zhang WJ, Ding JC, Peng BL, Pan X, Liu Y, Du J, Li Y, Liu ZY, Xie BL, Kuang ZJ, Yi J, Liu W
Nucleic acids research 2024 Jul 8;52(12):6811-6829
Nucleic acids research 2024 Jul 8;52(12):6811-6829
MBD3 promotes epithelial-mesenchymal transition in gastric cancer cells by upregulating ACTG1 via the PI3K/AKT pathway.
Wang H, Min J, Ding Y, Yu Z, Zhou Y, Wang S, Gong A, Xu M
Biological procedures online 2024 Jan 5;26(1):1
Biological procedures online 2024 Jan 5;26(1):1
Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells.
Dai W, Liu Z, Yan M, Nian X, Hong F, Zhou Z, Wang C, Fu X, Li X, Jiang M, Zhu Y, Huang Q, Lu X, Hou L, Yan N, Wang Q, Hu J, Mo W, Zhang X, Zhang L
Developmental cell 2024 Feb 26;59(4):482-495.e6
Developmental cell 2024 Feb 26;59(4):482-495.e6
MBD3 as a Potential Biomarker for Colon Cancer: Implications for Epithelial-Mesenchymal Transition (EMT) Pathways.
Ding Y, Wang H, Liu J, Jiang H, Gong A, Xu M
Cancers 2023 Jun 14;15(12)
Cancers 2023 Jun 14;15(12)
Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk.
Wang XH, Xu S, Zhou XY, Zhao R, Lin Y, Cao J, Zang WD, Tao H, Xu W, Li MQ, Zhao SM, Jin LP, Zhao JY
Nature communications 2021 Jun 8;12(1):3428
Nature communications 2021 Jun 8;12(1):3428
Demethylation of HACE1 gene promoter by propofol promotes autophagy of human A549 cells.
Li S, Yang H, Zhao M, Gong L, Wang Y, Lv Z, Quan Y, Wang Z
Oncology letters 2020 Dec;20(6):280
Oncology letters 2020 Dec;20(6):280
The Expression of MBD6 Is Associated with Tumor Size in Uterine Leiomyomas.
Liang MR, Zeng Y, Zeng SY, Zhang JW, Yang BC, Zhang ZY, Liu FY, Luo Y, Zou Y, Wang F, Huang OP
Genetic testing and molecular biomarkers 2019 Aug;23(8):523-532
Genetic testing and molecular biomarkers 2019 Aug;23(8):523-532
Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development.
Ma P, Pan H, Montgomery RL, Olson EN, Schultz RM
Proceedings of the National Academy of Sciences of the United States of America 2012 Feb 21;109(8):E481-9
Proceedings of the National Academy of Sciences of the United States of America 2012 Feb 21;109(8):E481-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Y79 cells were subjected to SDS PAGE followed by western blot with 14258-1-AP(MBD3 antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using MBD3 antibody 14258-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human endometrial cancer using 14258-1-AP(MBD3 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human endometrial cancer using 14258-1-AP(MBD3 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue