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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Product number
- ABIN356576 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- C-Term
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Biphasic kinetics of the human DNA repair protein MED1 (MBD4), a mismatch-specific DNA N-glycosylase.
Most microsatellite unstable sporadic colorectal carcinomas carry MBD4 mutations.
A mammalian protein with specific demethylase activity for mCpG DNA.
Identification and characterization of a family of mammalian methyl-CpG binding proteins.
Petronzelli F, Riccio A, Markham GD, Seeholzer SH, Stoerker J, Genuardi M, Yeung AT, Matsumoto Y, Bellacosa A
The Journal of biological chemistry 2000 Oct 20;275(42):32422-9
The Journal of biological chemistry 2000 Oct 20;275(42):32422-9
Most microsatellite unstable sporadic colorectal carcinomas carry MBD4 mutations.
Bader S, Walker M, Harrison D
British journal of cancer 2000 Dec;83(12):1646-9
British journal of cancer 2000 Dec;83(12):1646-9
A mammalian protein with specific demethylase activity for mCpG DNA.
Bhattacharya SK, Ramchandani S, Cervoni N, Szyf M
Nature 1999 Feb 18;397(6720):579-83
Nature 1999 Feb 18;397(6720):579-83
Identification and characterization of a family of mammalian methyl-CpG binding proteins.
Hendrich B, Bird A
Molecular and cellular biology 1998 Nov;18(11):6538-47
Molecular and cellular biology 1998 Nov;18(11):6538-47
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