Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 12166-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12166-1-AP, RRID:AB_10640583
- Product name
- Dysadherin antibody
- Antibody type
- Polyclonal
- Description
- Dysadherin antibody (Cat. #12166-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Discovery of New Markers for Haemogenic Endothelium and Haematopoietic Progenitors in the Mouse Yolk Sac.
USP11 stabilizes RALY to promote FXYD5-mediated aerobic glycolysis and aggravate pancreatic cancer progression.
FXYD5 regulates gastric cancer cell metastasis and drug resistance by EMT modulation.
Fxyd5 downregulation protects the heart from ischemia/reperfusion injury by suppressing myocardial inflammation.
miR-1180 Targets FXYD5 to Regulate Pancreatic Cancer Cells Migration and Invasion.
Generation of the novel anti-FXYD5 monoclonal antibody and its application to the diagnosis of pancreatic and lung cancer.
FXYD domain containing ion transport regulator 5 (FXYD5) silencing promotes cell viability and alleviates inflammatory response in cerulein-induced AR42J cells by blocking JAK2/STAT3 signaling pathway.
Development and Clinical Validation of a Seven-Gene Prognostic Signature Based on Multiple Machine Learning Algorithms in Kidney Cancer.
A FXYD5/TGF‑β/SMAD positive feedback loop drives epithelial‑to‑mesenchymal transition and promotes tumor growth and metastasis in ovarian cancer.
Diez-Pinel G, Muratore A, Ruhrberg C, Canu G
Journal of developmental biology 2026 Jan 6;14(1)
Journal of developmental biology 2026 Jan 6;14(1)
USP11 stabilizes RALY to promote FXYD5-mediated aerobic glycolysis and aggravate pancreatic cancer progression.
Xie H, Liao L, Li J, Cai R, He H, Lu M
Experimental cell research 2025 Oct 1;452(2):114758
Experimental cell research 2025 Oct 1;452(2):114758
FXYD5 regulates gastric cancer cell metastasis and drug resistance by EMT modulation.
Mao Y, Hu Y, Meng H, Qin J, An Q, Zhang C, Guo C, Zhao Y, Tan D, Ge X, Shi C
Cancer gene therapy 2025 Mar;32(3):318-326
Cancer gene therapy 2025 Mar;32(3):318-326
Fxyd5 downregulation protects the heart from ischemia/reperfusion injury by suppressing myocardial inflammation.
Zhang L, Xu J, Cui F, Jin J, Liu L, Wang L, Gao Y
Transplant immunology 2025 Dec;93:102282
Transplant immunology 2025 Dec;93:102282
miR-1180 Targets FXYD5 to Regulate Pancreatic Cancer Cells Migration and Invasion.
Xie H, Li J, Lu M, Zhang R, Mao H
Molecular biotechnology 2024 Nov;66(11):3182-3194
Molecular biotechnology 2024 Nov;66(11):3182-3194
Generation of the novel anti-FXYD5 monoclonal antibody and its application to the diagnosis of pancreatic and lung cancer.
Hotta T, Nariai Y, Kajitani N, Kadota K, Maruyama R, Tajima Y, Isobe T, Kamino H, Urano T
Biochimie 2023 May;208:160-169
Biochimie 2023 May;208:160-169
FXYD domain containing ion transport regulator 5 (FXYD5) silencing promotes cell viability and alleviates inflammatory response in cerulein-induced AR42J cells by blocking JAK2/STAT3 signaling pathway.
Ding L, Li J
Bioengineered 2022 Feb;13(2):2639-2647
Bioengineered 2022 Feb;13(2):2639-2647
Development and Clinical Validation of a Seven-Gene Prognostic Signature Based on Multiple Machine Learning Algorithms in Kidney Cancer.
Tian M, Wang T, Wang P
Cell transplantation 2021 Jan-Dec;30:963689720969176
Cell transplantation 2021 Jan-Dec;30:963689720969176
A FXYD5/TGF‑β/SMAD positive feedback loop drives epithelial‑to‑mesenchymal transition and promotes tumor growth and metastasis in ovarian cancer.
Bai Y, Li LD, Li J, Chen RF, Yu HL, Sun HF, Wang JY, Lu X
International journal of oncology 2020 Jan;56(1):301-314
International journal of oncology 2020 Jan;56(1):301-314
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse small intestine tissue were subjected to SDS PAGE followed by western blot with 12166-1-AP(FXYD5 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 12166-1-AP(FXYD5 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The Dysadherin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Dysadherin. This antibody recognizes human, mouse antigen. The Dysadherin antibody has been validated for the following applications: ELISA, WB, IHC analysis.