MAB1828

antibody from Novus Biologicals

Targeting: TREM2 TREM-2, Trem2a, Trem2b, Trem2c

Western blot (Data presented on provider website)

Antibody Data

Product number

MAB1828

Provider

Novus Biologicals

Product name

Mouse Monoclonal TREM2 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects human TREM2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human TREM1, recombinant mouse (rm) TREM2b, or rmTREM3 is observed.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

References

Submitted references

A data-driven approach links microglia to pathology and prognosis in amyotrophic lateral sclerosis.

Cooper-Knock J, Green C, Altschuler G, Wei W, Bury JJ, Heath PR, Wyles M, Gelsthorpe C, Highley JR, Lorente-Pons A, Beck T, Doyle K, Otero K, Traynor B, Kirby J, Shaw PJ, Hide W
Acta neuropathologica communications 2017 Mar 16;5(1):23

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TREM-2 binds to lipooligosaccharides of Neisseria gonorrhoeae and is expressed on reproductive tract epithelial cells.

Quan DN, Cooper MD, Potter JL, Roberts MH, Cheng H, Jarvis GA
Mucosal immunology 2008 May;1(3):229-38

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Pathological role of osteoclast costimulation in arthritis-induced bone loss.

Ochi S, Shinohara M, Sato K, Gober HJ, Koga T, Kodama T, Takai T, Miyasaka N, Takayanagi H
Proceedings of the National Academy of Sciences of the United States of America 2007 Jul 3;104(27):11394-9