Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Flow cytometry [3]
Submit
Validation data
Reference
Comment
Report error
- Product number
- FAB17291A - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rat Monoclonal TREM2 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human and mouse TREM-2 in direct ELISAs and Western blots. Stains TREM-2 transfectants but not TREM-1 transfectants.
- Reactivity
- Human, Mouse
- Host
- Rat
- Conjugate
- Red dye
- Isotype
- IgG
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.
Submitted references TREM2-activating antibodies abrogate the negative pleiotropic effects of the Alzheimer's disease variant Trem2R47H on murine myeloid cell function.
Increased TREM-2 expression on the subsets of CD11c+ cells in the lungs and lymph nodes during allergic airway inflammation.
CD33 modulates TREM2: convergence of Alzheimer loci.
Cheng Q, Danao J, Talreja S, Wen P, Yin J, Sun N, Li CM, Chui D, Tran D, Koirala S, Chen H, Foltz IN, Wang S, Sambashivan S
The Journal of biological chemistry 2018 Aug 10;293(32):12620-12633
The Journal of biological chemistry 2018 Aug 10;293(32):12620-12633
Increased TREM-2 expression on the subsets of CD11c+ cells in the lungs and lymph nodes during allergic airway inflammation.
Hall SC, Agrawal DK
Scientific reports 2017 Sep 19;7(1):11853
Scientific reports 2017 Sep 19;7(1):11853
CD33 modulates TREM2: convergence of Alzheimer loci.
Chan G, White CC, Winn PA, Cimpean M, Replogle JM, Glick LR, Cuerdon NE, Ryan KJ, Johnson KA, Schneider JA, Bennett DA, Chibnik LB, Sperling RA, Bradshaw EM, De Jager PL
Nature neuroscience 2015 Nov;18(11):1556-8
Nature neuroscience 2015 Nov;18(11):1556-8
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of TREM-2 in HEK Human Cell Line Transfected with Human TREM-2 and eGFP by Flow Cytometry. Detection of TREM-2 in HEK Human Cell Line Transfected with Human TREM-2 and eGFP by Flow Cytometry.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of TREM-2 in RAW 264.7 Mouse Cell Line by Flow Cytometry. Detection of TREM-2 in RAW 264.7 Mouse Cell Line by Flow Cytometry.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of TREM-2 in Human Blood Monocytes by Flow Cytometry. Detection of TREM-2 in Human Blood Monocytes by Flow Cytometry.