Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- MAB2056 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB2056, RRID:AB_1716445
- Product name
- TREM2 monoclonal antibody, clone 2B5
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against partial recombinant TREM2.
- Isotype
- IgG
- Antibody clone number
- 2B5
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria.
Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation.
N'Diaye EN, Branda CS, Branda SS, Nevarez L, Colonna M, Lowell C, Hamerman JA, Seaman WE
The Journal of cell biology 2009 Jan 26;184(2):215-23
The Journal of cell biology 2009 Jan 26;184(2):215-23
Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation.
Piccio L, Buonsanti C, Cella M, Tassi I, Schmidt RE, Fenoglio C, Rinker J 2nd, Naismith RT, Panina-Bordignon P, Passini N, Galimberti D, Scarpini E, Colonna M, Cross AH
Brain : a journal of neurology 2008 Nov;131(Pt 11):3081-91
Brain : a journal of neurology 2008 Nov;131(Pt 11):3081-91
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Supportive validation
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- Abnova Corporation (provider)
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- Experimental details
- Cell lysates of HeLa (lane 1), MCF-7 (lane 2), LNCaP (lane 3) and mouse brain (lane 4) (30 ug) were resolved by SDS-PAGE and probed with TREM2 monoclonal antibody, clone 2B5 (Cat # MAB2056) (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.