27599-1-AP

antibody from Proteintech Group

Targeting: TREM2 TREM-2, Trem2a, Trem2b, Trem2c

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

27599-1-AP

Provider

Proteintech Group

Product name

TREM2 antibody

Antibody type

Polyclonal

Description

TREM2 antibody (Cat. #27599-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human and has been validated for the following applications: IHC,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

TREM2 deficiency impairs the energy metabolism of Schwann cells and exacerbates peripheral neurological deficits.

Zhang N, Ji Q, Chen Y, Wen X, Shan F
Cell death & disease 2024 Mar 7;15(3):193

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TREM2 regulates BV2 microglia activation and influences corticosterone-induced neuroinflammation in depressive disorders.

Shi J, Wang X, Kang C, Liu J, Ma C, Yang L, Hu J, Zhao N
Brain research 2024 Jan 1;1822:148664

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A single cell atlas of frozen shoulder capsule identifies features associated with inflammatory fibrosis resolution.

Ng MTH, Borst R, Gacaferi H, Davidson S, Ackerman JE, Johnson PA, Machado CC, Reekie I, Attar M, Windell D, Kurowska-Stolarska M, MacDonald L, Alivernini S, Garvilles M, Jansen K, Bhalla A, Lee A, Charlesworth J, Chowdhury R, Klenerman P, Powell K, Hackstein CP, ICECAP Consortium, Furniss D, Rees J, Gilroy D, Coles M, Carr AJ, Sansom SN, Buckley CD, Dakin SG
Nature communications 2024 Feb 19;15(1):1394

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Identification of TREM2-positive tumor-associated macrophages in esophageal squamous cell carcinoma: implication for poor prognosis and immunotherapy modulation.

Li H, Miao Y, Zhong L, Feng S, Xu Y, Tang L, Wu C, Zhang X, Gu L, Diao H, Wang H, Wen Z, Yang M
Frontiers in immunology 2023;14:1162032

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Soluble TREM2 ameliorates tau phosphorylation and cognitive deficits through activating transgelin-2 in Alzheimer's disease.

Zhang X, Tang L, Yang J, Meng L, Chen J, Zhou L, Wang J, Xiong M, Zhang Z
Nature communications 2023 Oct 21;14(1):6670

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TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma.

Sun R, Han R, McCornack C, Khan S, Tabor GT, Chen Y, Hou J, Jiang H, Schoch KM, Mao DD, Cleary R, Yang A, Liu Q, Luo J, Petti A, Miller TM, Ulrich JD, Holtzman DM, Kim AH
Science advances 2023 May 12;9(19):eade3559

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Heterogeneity of tumor microenvironment is associated with clinical prognosis of non-clear cell renal cell carcinoma: a single-cell genomics study.

Chen WJ, Cao H, Cao JW, Zuo L, Qu FJ, Xu D, Zhang H, Gong HY, Chen JX, Ye JQ, Gan SS, Zhou W, Zhu DW, Pan XW, Cui XG
Cell death & disease 2022 Jan 11;13(1):50