HPA010917

antibody from Atlas Antibodies

Targeting: TREM2 TREM-2, Trem2a, Trem2b, Trem2c

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA010917

Provider

Atlas Antibodies

Product name

Anti-TREM2

Antibody type

Polyclonal

Antigen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence

Description

Affinity purified using the PrEST antigen as affinity ligand

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

AAWHGQKPGTHPPSELDCGHDPGYQLQTLPGLRDT


Isotype

IgG

Vial size

100 µl

Storage

Store at +4°C for short term storage (1-2 days). Long time storage is recommended at -20°C. If stored at lower temperature, aliquot to avoid repeated freezing and thawing. Working dilution samples should be discarded if not used within 12 hours.

References

Submitted references

Do Alzheimer's Disease Risk Gene Products Actually Act in Microglia?

Hashioka S, Inoue K, Takeshita H, Inagaki M
Frontiers in Aging Neuroscience 2020;12

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TREM2 expression in the human brain: a marker of monocyte recruitment?

Fahrenhold M, Rakic S, Classey J, Brayne C, Ince P, Nicoll J, Boche D
Brain Pathology 2017;28(5):595-602

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A survey of TREM2 antibodies reveals neuronal but not microglial staining in formalin-fixed paraffin-embedded postmortem Alzheimer's brain tissues

Satoh J, Kawana N, Yamamoto Y, Ishida T, Saito Y, Arima K
Alzheimer's Research & Therapy 2013;5(4):30

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The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints

Crotti T, Dharmapatni A, Alias E, Zannettino A, Smith M, Haynes D
Arthritis Research & Therapy 2012;14(6)