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- Antibody Data
- Antigen structure
- References [13]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 22980-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- PRODH antibody
- Antibody type
- Polyclonal
- Description
- PRODH antibody (Cat. #22980-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Proline restores mitochondrial function and reverses aging hallmarks in senescent cells.
Mechanical stiffness promotes skin fibrosis through Piezo1-mediated arginine and proline metabolism.
Silencing of Dicer enhances dacarbazine resistance in melanoma cells by inhibiting ADSL expression.
Proline promotes proliferation and drug resistance of multiple myeloma by downregulation of proline dehydrogenase.
PYCR1 promotes the malignant progression of lung cancer through the JAK-STAT3 signaling pathway via PRODH-dependent glutamine synthesize.
High levels of Myc expression are required for the robust proliferation of hepatocytes, but not for the sustained weak proliferation.
Beneficial Effect of Proline Supplementation on Goat Spermatozoa Quality during Cryopreservation.
Discordant regulation of eIF2 kinase GCN2 and mTORC1 during nutrient stress.
Activation of proline metabolism maintains ATP levels during cocaine-induced polyADP-ribosylation.
PINCH-1 promotes Δ(1)-pyrroline-5-carboxylate synthase expression and contributes to proline metabolic reprogramming in lung adenocarcinoma.
Metabolomic Analysis of the Ameliorative Effect of Enhanced Proline Metabolism on Hypoxia-Induced Injury in Cardiomyocytes.
Proline Protects Boar Sperm against Oxidative Stress through Proline Dehydrogenase-Mediated Metabolism and the Amine Structure of Pyrrolidine.
Kindlin-2 links mechano-environment to proline synthesis and tumor growth.
Choudhury D, Rong N, Senthil Kumar HV, Swedick S, Samuel RZ, Mehrotra P, Toftegaard J, Rajabian N, Thiyagarajan R, Podder AK, Wu Y, Shahini S, Seldeen KL, Troen B, Lei P, Andreadis ST
Cell reports 2024 Feb 27;43(2):113738
Cell reports 2024 Feb 27;43(2):113738
Mechanical stiffness promotes skin fibrosis through Piezo1-mediated arginine and proline metabolism.
He J, Fang B, Shan S, Li Q
Cell death discovery 2023 Sep 26;9(1):354
Cell death discovery 2023 Sep 26;9(1):354
Silencing of Dicer enhances dacarbazine resistance in melanoma cells by inhibiting ADSL expression.
Yeh YW, Hsu TW, Su YH, Wang CH, Liao PH, Chiu CF, Tseng PC, Chen TM, Lee WR, Tzeng YS
Aging 2023 Nov 15;15(22):12873-12889
Aging 2023 Nov 15;15(22):12873-12889
Proline promotes proliferation and drug resistance of multiple myeloma by downregulation of proline dehydrogenase.
Zhang J, Shi F, Liu X, Wu X, Hu C, Guo J, Yang Q, Xia J, He Y, An G, Qiu L, Feng X, Zhou W
British journal of haematology 2023 May;201(4):704-717
British journal of haematology 2023 May;201(4):704-717
PYCR1 promotes the malignant progression of lung cancer through the JAK-STAT3 signaling pathway via PRODH-dependent glutamine synthesize.
Zhang L, Zhao X, Wang E, Yang Y, Hu L, Xu H, Zhang B
Translational oncology 2023 Jun;32:101667
Translational oncology 2023 Jun;32:101667
High levels of Myc expression are required for the robust proliferation of hepatocytes, but not for the sustained weak proliferation.
Goto M, Ooshio T, Yamamoto M, Tanaka H, Fujii Y, Meng L, Kamikokura Y, Okada Y, Nishikawa Y
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166644
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166644
Beneficial Effect of Proline Supplementation on Goat Spermatozoa Quality during Cryopreservation.
Zhang W, Min L, Li Y, Lang Y, Hoque SAM, Adetunji AO, Zhu Z
Animals : an open access journal from MDPI 2022 Sep 30;12(19)
Animals : an open access journal from MDPI 2022 Sep 30;12(19)
Discordant regulation of eIF2 kinase GCN2 and mTORC1 during nutrient stress.
Misra J, Holmes MJ, T Mirek E, Langevin M, Kim HG, Carlson KR, Watford M, Dong XC, Anthony TG, Wek RC
Nucleic acids research 2021 Jun 4;49(10):5726-5742
Nucleic acids research 2021 Jun 4;49(10):5726-5742
Activation of proline metabolism maintains ATP levels during cocaine-induced polyADP-ribosylation.
Dash S, Dash C, Pandhare J
Amino acids 2021 Dec;53(12):1903-1915
Amino acids 2021 Dec;53(12):1903-1915
PINCH-1 promotes Δ(1)-pyrroline-5-carboxylate synthase expression and contributes to proline metabolic reprogramming in lung adenocarcinoma.
Cui C, Wang J, Guo L, Wu C
Amino acids 2021 Dec;53(12):1875-1890
Amino acids 2021 Dec;53(12):1875-1890
Metabolomic Analysis of the Ameliorative Effect of Enhanced Proline Metabolism on Hypoxia-Induced Injury in Cardiomyocytes.
Wang J, Xue Z, Hua C, Lin J, Shen Z, Song Y, Ying H, Lv Q, Wang M, Zhou B
Oxidative medicine and cellular longevity 2020;2020:8866946
Oxidative medicine and cellular longevity 2020;2020:8866946
Proline Protects Boar Sperm against Oxidative Stress through Proline Dehydrogenase-Mediated Metabolism and the Amine Structure of Pyrrolidine.
Feng C, Zhu Z, Bai W, Li R, Zheng Y, Tian X, Wu D, Lu H, Wang Y, Zeng W
Animals : an open access journal from MDPI 2020 Sep 1;10(9)
Animals : an open access journal from MDPI 2020 Sep 1;10(9)
Kindlin-2 links mechano-environment to proline synthesis and tumor growth.
Guo L, Cui C, Zhang K, Wang J, Wang Y, Lu Y, Chen K, Yuan J, Xiao G, Tang B, Sun Y, Wu C
Nature communications 2019 Feb 19;10(1):845
Nature communications 2019 Feb 19;10(1):845
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 22980-1-AP(PRODH antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PRODH antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PRODH. This antibody recognizes human, mouse antigen. The PRODH antibody has been validated for the following applications: ELISA, WB, IHC analysis.
