Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 17594-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17594-1-AP, RRID:AB_10694429
- Product name
- SMYD4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SMYD4 antibody (Cat. #17594-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The genetic landscape of primary malignant melanoma of the cervix using integrated bioinformatics analysis and whole-exome sequencing.
SMYD4 promotes MYH9 ubiquitination through lysine monomethylation modification to inhibit breast cancer progression.
SMYD4 monomethylates PRMT5 and forms a positive feedback loop to promote hepatocellular carcinoma progression.
The roles of SMYD4 in epigenetic regulation of cardiac development in zebrafish.
Zhou J, Xu T, Chen C, Ping Y
Frontiers in oncology 2025;15:1597153
Frontiers in oncology 2025;15:1597153
SMYD4 promotes MYH9 ubiquitination through lysine monomethylation modification to inhibit breast cancer progression.
Yang JS, Cao JM, Sun R, Zhou XJ, Chen ZH, Liu BW, Liu XF, Yu Y, Wang X
Breast cancer research : BCR 2025 Feb 10;27(1):20
Breast cancer research : BCR 2025 Feb 10;27(1):20
SMYD4 monomethylates PRMT5 and forms a positive feedback loop to promote hepatocellular carcinoma progression.
Zhou Z, Chen Z, Zhou Q, Meng S, Shi J, Mui S, Jiang H, Lin J, He G, Li W, Zhang J, Wang J, He C, Yan Y, Xiao Z
Cancer science 2024 May;115(5):1587-1601
Cancer science 2024 May;115(5):1587-1601
The roles of SMYD4 in epigenetic regulation of cardiac development in zebrafish.
Xiao D, Wang H, Hao L, Guo X, Ma X, Qian Y, Chen H, Ma J, Zhang J, Sheng W, Shou W, Huang G, Ma D
PLoS genetics 2018 Aug;14(8):e1007578
PLoS genetics 2018 Aug;14(8):e1007578
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 17594-1-AP(SMYD4 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas using 17594-1-AP(SMYD4 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The SMYD4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human SMYD4. This antibody recognizes human, mouse, rat antigen. The SMYD4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.