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SPRED1
gene productFLJ33903, PPP1R147
The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008]
Featured antibodies
 Atlas Antibodies |
 HPA042193 |
1 references | Polyclonal |
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 GeneTex |
GTX85376 |
0 references | Polyclonal |
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