26486-1-AP

antibody from Proteintech Group

Targeting: SLC2A9 Glut9, GLUTX, URATv1

Provider product page for 26486-1-AP

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Product number: 26486-1-AP - Provider product page
Provider: Proteintech Group
Product name: SLC2A9 antibody
Antibody type: Polyclonal
Description: SLC2A9 antibody (Cat. #26486-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

SLC2A9 protein structure - 26486-1-AP shown in red.

Submitted references The impact of chrysanthemi indici flos-enriched flavonoid part on the model of hyperuricemia based on inhibiting synthesis and promoting excretion of uric acid.

Jiao L, Wang R, Dong Y, Su J, Yu J, Yan M, Chen S, Lv G
Journal of ethnopharmacology 2024 Oct 28;333:118488

Lactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model.

Fu Y, Chen YS, Xia DY, Luo XD, Luo HT, Pan J, Ma WQ, Li JZ, Mo QY, Tu Q, Li MM, Zhao Y, Li Y, Huang YT, Chen ZX, Li ZJ, Bernard L, Dione M, Zhang YM, Miao K, Chen JY, Zhu SS, Ren J, Zhou LJ, Jiang XZ, Chen J, Lin ZP, Chen JP, Ye H, Cao QY, Zhu YW, Yang L, Wang X, Wang WC
NPJ biofilms and microbiomes 2024 Mar 20;10(1):25

Catalpol ameliorates fructose-induced renal inflammation by inhibiting TLR4/MyD88 signaling and uric acid reabsorption.

Chen Y, Liu Q, Meng X, Zhao L, Zheng X, Feng W
European journal of pharmacology 2024 Mar 15;967:176356

Integrating multi-level interactive network and in vivo/vitro studies to explore the protective mechanism of Ampelopsis grossedentata in hyperuricemia.

Zhou QX, Zhou Q, Zhang P, Xie YQ, Yang ZY, Tan WH, Khan A, Duan WG, Zhou ZH, Liu L
Fitoterapia 2024 Jan;172:105718

Chinese Sumac (Rhus chinensis Mill.) Fruits Prevent Hyperuricemia and Uric Acid Nephropathy in Mice Fed a High-Purine Yeast Diet.

Ma N, Cai S, Sun Y, Chu C
Nutrients 2024 Jan 5;16(2)

Fuling-Zexie formula attenuates hyperuricemia-induced nephropathy and inhibits JAK2/STAT3 signaling and NLRP3 inflammasome activation in mice.

Lu M, Yin J, Xu T, Dai X, Liu T, Zhang Y, Wang S, Liu Y, Shi H, Zhang Y, Mo F, Sukhorukov V, Orekhov AN, Gao S, Wang L, Zhang D
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117262

Data mining-guided alleviation of hyperuricemia by Paeonia veitchii Lynch through inhibition of xanthine oxidase and regulation of renal urate transporters.

Du J, Wang N, Yu D, He P, Gao Y, Tu Y, Li Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155305

Punicalagin attenuates hyperuricemia via restoring hyperuricemia-induced renal and intestinal dysfunctions.

Han QQ, Ren QD, Guo X, Farag MA, Zhang YH, Zhang MQ, Chen YY, Sun ST, Sun JY, Li NY, Liu C
Journal of advanced research 2024 Apr 10;

Paeonia × suffruticosa Andrews leaf extract and its main component apigenin 7-O-glucoside ameliorate hyperuricemia by inhibiting xanthine oxidase activity and regulating renal urate transporters.

Zhang Y, Li Y, Li C, Zhao Y, Xu L, Ma S, Lin F, Xie Y, An J, Wang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154957

Whey protein peptides PEW and LLW synergistically ameliorate hyperuricemia and modulate gut microbiota in potassium oxonate and hypoxanthine-induced hyperuricemic rats.

Qi X, Guan K, Liu C, Chen H, Ma Y, Wang R
Journal of dairy science 2023 Nov;106(11):7367-7381

Amelioration effects of α-viniferin on hyperuricemia and hyperuricemia-induced kidney injury in mice.

Guo XL, Gao YY, Yang YX, Zhu QF, Guan HY, He X, Zhang CL, Wang Y, Xu GB, Zou SH, Wei MC, Zhang J, Zhang JJ, Liao SG
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154868

Oxyberberrubine, a novel liver microsomes-mediated secondary metabolite of berberine, alleviates hyperuricemic nephropathy in mice.

Zhong L, Lin Y, Gong S, Wu X, Liu Y, Chen J, Li Y, Yan F, Su Z, Xie Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154521

Hypouricemic and nephroprotective effects of palmatine from Cortex Phellodendri Amurensis: A uric acid modulator targeting Keap1-Nrf2/NLRP3 axis.

Ai G, Huang R, Xie J, Zhong L, Wu X, Qin Z, Su Z, Chen J, Yang X, Dou Y
Journal of ethnopharmacology 2023 Jan 30;301:115775

Naringenin Ameliorates Hyperuricemia by Regulating Renal Uric Acid Excretion via the PI3K/AKT Signaling Pathway and Renal Inflammation through the NF-κB Signaling Pathway.

Yang B, Xin M, Liang S, Huang Y, Li J, Wang C, Liu C, Song X, Sun J, Sun W
Journal of agricultural and food chemistry 2023 Jan 25;71(3):1434-1446

Ferulic acid supplementation alleviates hyperuricemia in high-fructose/fat diet-fed rats via promoting uric acid excretion and mediating the gut microbiota.

Zhang N, Zhou J, Zhao L, Zhao Z, Wang S, Zhang L, Zhou F
Food & function 2023 Feb 6;14(3):1710-1725

The antihyperuricemia activity of Astragali Radix through regulating the expression of uric acid transporters via PI3K/Akt signalling pathway.

Zhang MQ, Sun KX, Guo X, Chen YY, Feng CY, Chen JS, Barreira JCM, Prieto MA, Sun JY, Zhang JD, Li NY, Liu C
Journal of ethnopharmacology 2023 Dec 5;317:116770

Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.

Zhang Y, Wang S, Dai X, Liu T, Liu Y, Shi H, Yin J, Xu T, Zhang Y, Zhao D, Sukhorukov V, Orekhov AN, Gao S, Wang L, Zhang D
Journal of ethnopharmacology 2023 Aug 10;312:116530

Diacylated anthocyanins from purple sweet potato (Ipomoeabatatas L.) attenuate hyperglycemia and hyperuricemia in mice induced by a high-fructose/high-fat diet.

Shen L, Yang Y, Zhang J, Feng L, Zhou Q
Journal of Zhejiang University. Science. B 2023 Apr 15;24(7):587-601

Berberine Attenuates Hyperuricemia by Regulating Urate Transporters and Gut Microbiota.

Shan B, Wu M, Chen T, Tang W, Li P, Chen J
The American journal of Chinese medicine 2022;50(8):2199-2221

Therapeutic effects and mechanisms of N-(9,10-anthraquinone-2-ylcarbonyl) xanthine oxidase inhibitors on hyperuricemia.

Gao T, Xu J, Xiao Y, Li J, Hu W, Su X, Shen X, Yu W, Chen Z, Huang B, Li H, Wang X
Frontiers in pharmacology 2022;13:950699

Autophagy-dependent Na(+)-K(+)-ATPase signalling and abnormal urate reabsorption in hyperuricaemia-induced renal tubular injury.

Guan H, Lin H, Wang X, Xu Y, Zheng Y, Zhou X, Diao X, Ye Z, Xiao J
European journal of pharmacology 2022 Oct 15;932:175237

Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway.

Liu T, Gao H, Zhang Y, Wang S, Lu M, Dai X, Liu Y, Shi H, Xu T, Yin J, Gao S, Wang L, Zhang D
Pharmaceuticals (Basel, Switzerland) 2022 Nov 21;15(11)

Effects of black tea and black brick tea with fungal growth on lowering uric acid levels in hyperuricemic mice.

Yuan D, Lin L, Peng Y, Zhou Y, Li L, Xiao W, Gong Z
Journal of food biochemistry 2022 Jul;46(7):e14140

Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium Oxonate- and Hypoxanthine-Induced Hyperuricemic Mice.

Xu L, Lin G, Yu Q, Li Q, Mai L, Cheng J, Xie J, Liu Y, Su Z, Li Y
Frontiers in pharmacology 2021;12:645879

Sonneratia apetala seed oil attenuates potassium oxonate/hypoxanthine-induced hyperuricemia and renal injury in mice.

Chen J, Xu L, Jiang L, Wu Y, Wei L, Wu X, Xiao S, Liu Y, Gao C, Cai J, Su Z
Food & function 2021 Oct 4;12(19):9416-9431

Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.

Zhao X, Wang J, Tang L, Li P, Ru J, Bai Y
Bioengineered 2021 Dec;12(1):589-600

Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway.

Lin G, Yu Q, Xu L, Huang Z, Mai L, Jiang L, Su Z, Xie J, Li Y, Liu Y, Lin Z, Chen J
European journal of pharmacology 2021 Dec 5;912:174592

Resveratrol affects the expression of uric acid transporter by improving inflammation.

Zhang X, Nie Q, Zhang Z, Zhao J, Zhang F, Wang C, Wang X, Song G
Molecular medicine reports 2021 Aug;24(2)

Anti-hyperuricemic potential of stevia (Stevia rebaudiana Bertoni) residue extract in hyperuricemic mice.

Mehmood A, Zhao L, Ishaq M, Xin W, Zhao L, Wang C, Hossen I, Zhang H, Lian Y, Xu M
Food & function 2020 Jul 22;11(7):6387-6406

MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.

Zhou Z, Dong Y, Zhou H, Liu J, Zhao W
Biochemical and biophysical research communications 2019 Sep 24;517(3):413-420

Conjugated Linoleic Acid Ameliorates High Fructose-Induced Hyperuricemia and Renal Inflammation in Rats via NLRP3 Inflammasome and TLR4 Signaling Pathway.

Tan J, Wan L, Chen X, Li X, Hao X, Li X, Li J, Ding H
Molecular nutrition & food research 2019 Jun;63(12):e1801402

Impaired Na(+)-K(+)-ATPase signaling in renal proximal tubule contributes to hyperuricemia-induced renal tubular injury.

Xiao J, Zhang X, Fu C, Yang Q, Xie Y, Zhang Z, Ye Z
Experimental & molecular medicine 2018 Mar 2;50(3):e452

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