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- References [9]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 13676-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13676-1-AP, RRID:AB_10697831
- Product name
- WDR1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated WDR1 antibody (Cat. #13676-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references YAP signaling is involved in WDR1-regulated proliferation and migration of non-small-cell lung cancer cells.
WD Repeat Domain 1 Deficiency Inhibits Neointima Formation in Mice Carotid Artery by Modulation of Smooth Muscle Cell Migration and Proliferation.
Hippocampal Wdr1 Deficit Impairs Learning and Memory by Perturbing F-actin Depolymerization in Mice.
Knockout of Wdr1 results in cardiac hypertrophy and impaired cardiac function in adult mouse heart.
WDR1 Promotes Cell Growth and Migration and Contributes to Malignant Phenotypes of Non-small Cell Lung Cancer through ADF/cofilin-mediated Actin Dynamics.
WDR1-regulated actin dynamics is required for outflow tract and right ventricle development.
Trp-Asp (WD) Repeat Domain 1 Is Essential for Mouse Peri-implantation Development and Regulates Cofilin Phosphorylation.
AIP1-mediated actin disassembly is required for postnatal germ cell migration and spermatogonial stem cell niche establishment.
A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice.
An R, Wang J, Chen X, Xu R, Hu J, Liu Z, Wei C, Zhang C, Yuan B
Experimental biology and medicine (Maywood, N.J.) 2022 Sep;247(18):1619-1629
Experimental biology and medicine (Maywood, N.J.) 2022 Sep;247(18):1619-1629
WD Repeat Domain 1 Deficiency Inhibits Neointima Formation in Mice Carotid Artery by Modulation of Smooth Muscle Cell Migration and Proliferation.
Hu J, Pi S, Xiong M, Liu Z, Huang X, An R, Zhang T, Yuan B
Molecules and cells 2020 Aug 31;43(8):749-762
Molecules and cells 2020 Aug 31;43(8):749-762
Hippocampal Wdr1 Deficit Impairs Learning and Memory by Perturbing F-actin Depolymerization in Mice.
Wang J, Kou XL, Chen C, Wang M, Qi C, Wang J, You WY, Hu G, Chen J, Gao J
Cerebral cortex (New York, N.Y. : 1991) 2019 Sep 13;29(10):4194-4207
Cerebral cortex (New York, N.Y. : 1991) 2019 Sep 13;29(10):4194-4207
Knockout of Wdr1 results in cardiac hypertrophy and impaired cardiac function in adult mouse heart.
Huang X, Li Z, Hu J, Yang Z, Liu Z, Zhang T, Zhang C, Yuan B
Gene 2019 May 20;697:40-47
Gene 2019 May 20;697:40-47
WDR1 Promotes Cell Growth and Migration and Contributes to Malignant Phenotypes of Non-small Cell Lung Cancer through ADF/cofilin-mediated Actin Dynamics.
Yuan B, Zhang R, Hu J, Liu Z, Yang C, Zhang T, Zhang C
International journal of biological sciences 2018;14(9):1067-1080
International journal of biological sciences 2018;14(9):1067-1080
WDR1-regulated actin dynamics is required for outflow tract and right ventricle development.
Hu J, Shi Y, Xia M, Liu Z, Zhang R, Luo H, Zhang T, Yang Z, Yuan B
Developmental biology 2018 Jun 15;438(2):124-137
Developmental biology 2018 Jun 15;438(2):124-137
Trp-Asp (WD) Repeat Domain 1 Is Essential for Mouse Peri-implantation Development and Regulates Cofilin Phosphorylation.
Xiao Y, Ma H, Wan P, Qin D, Wang X, Zhang X, Xiang Y, Liu W, Chen J, Yi Z, Li L
The Journal of biological chemistry 2017 Jan 27;292(4):1438-1448
The Journal of biological chemistry 2017 Jan 27;292(4):1438-1448
AIP1-mediated actin disassembly is required for postnatal germ cell migration and spermatogonial stem cell niche establishment.
Xu J, Wan P, Wang M, Zhang J, Gao X, Hu B, Han J, Chen L, Sun K, Wu J, Wu X, Huang X, Chen J
Cell death & disease 2015 Jul 16;6(7):e1818
Cell death & disease 2015 Jul 16;6(7):e1818
A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice.
Yuan B, Wan P, Chu D, Nie J, Cao Y, Luo W, Lu S, Chen J, Yang Z
The American journal of pathology 2014 Jul;184(7):1967-80
The American journal of pathology 2014 Jul;184(7):1967-80
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 13676-1-AP(WDR1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 13676-1-AP(WDR1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The WDR1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human WDR1. This antibody recognizes human,mouse,rat antigen. The WDR1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
