66481-1-Ig

antibody from Proteintech Group

Targeting: CD276 B7-H3, B7H3, B7RP-2

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

66481-1-Ig

Provider

Proteintech Group

Product name

B7-H3 antibody

Antibody type

Monoclonal

Description

KD/KO validated B7-H3 antibody (Cat. #66481-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Pig and has been validated for the following applications: FC, IF, IHC, WB,ELISA.

Reactivity

Human, Porcine

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1E7D1

Vial size

20ul, 150ul

References

Submitted references

Comprehensive Analysis Reveals Distinct Immunological and Prognostic Characteristics of CD276/B7-H3 in Pan-Cancer.

Ding J, Sun Y, Sulaiman Z, Li C, Cheng Z, Liu S
International journal of general medicine 2023;16:367-391

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Enhancement of CAR-T cell activity against cholangiocarcinoma by simultaneous knockdown of six inhibitory membrane proteins.

Qiao Y, Chen J, Wang X, Yan S, Tan J, Xia B, Chen Y, Lin K, Zou F, Liu B, He X, Zhang Y, Zhang X, Zhang H, Wu X, Lu L
Cancer communications (London, England) 2023 Jul;43(7):788-807

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B7-H3 and CD47 co-expression in gastric cancer is a predictor of poor prognosis and potential targets for future dual-targeting immunotherapy.

Chen S, Zhan S, Ding S, Zhang Q, Xuan H, Zhang X, Cao L
Journal of cancer research and clinical oncology 2023 Dec;149(18):16609-16621

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Genome-scale CRISPR-Cas9 screen reveals novel regulators of B7-H3 in tumor cells.

Zhao S, Wang Y, Yang N, Mu M, Wu Z, Li H, Tang X, Zhong K, Zhang Z, Huang C, Cao T, Zheng M, Wang G, Nie C, Yang H, Guo G, Zhou L, Zheng X, Tong A
Journal for immunotherapy of cancer 2022 Jun;10(6)

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An N-glycoproteomic site-mapping analysis reveals glycoprotein alterations in esophageal squamous cell carcinoma.

Gao Y, Shen L, Dong T, Yang X, Cui H, Guo Y, Ma Y, Kong P, Cheng X, Zhang L, Cui Y
Journal of translational medicine 2022 Jun 25;20(1):285

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TROP-2, Nectin-4, GPNMB, and B7-H3 Are Potentially Therapeutic Targets for Anaplastic Thyroid Carcinoma.

Toda S, Sato S, Saito N, Sekihara K, Matsui A, Murayama D, Nakayama H, Suganuma N, Okubo Y, Hayashi H, Iwasaki H, Miyagi Y, Hoshino D
Cancers 2022 Jan 24;14(3)

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B7-H3 inhibits apoptosis of gastric cancer cell by interacting with Fibronectin.

Sun M, Xie J, Zhang D, Chen C, Lin S, Chen Y, Zhang G
Journal of Cancer 2021;12(24):7518-7526

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Fibronectin enhances tumor metastasis through B7-H3 in clear cell renal cell carcinoma.

Xie J, Sun M, Zhang D, Chen C, Lin S, Zhang G
FEBS open bio 2021 Nov;11(11):2977-2987