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- References [12]
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- Product number
- 12545-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12545-1-AP, RRID:AB_2268102
- Product name
- PEX5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PEX5 antibody (Cat. #12545-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hepatitis C virus alters the morphology and function of peroxisomes.
Comparison of human PEX knockout cell lines suggests a dual role of PEX1 in peroxisome biogenesis.
Circular RNA Sec61 subunit alpha isoform 1 by competitive absorption of microRNA-513a-5p mediates peroxisomal biogenesis factor 5 expression and promotes the malignant phenotype of non-small cell lung cancer.
Silencing PEX26 as an unconventional mode to kill drug-resistant cancer cells and forestall drug resistance.
PEX5 prevents cardiomyocyte hypertrophy via suppressing the redox-sensitive signaling pathways MAPKs and STAT3.
Pkd1 Mutation Has No Apparent Effects on Peroxisome Structure or Lipid Metabolism.
Resolving monocytes generated through TRAM deletion attenuate atherosclerosis.
Aging lowers PEX5 levels in cortical neurons in male and female mouse brains.
Ceramide regulates interaction of Hsd17b4 with Pex5 and function of peroxisomes.
ATM functions at the peroxisome to induce pexophagy in response to ROS.
A novel type of rhizomelic chondrodysplasia punctata, RCDP5, is caused by loss of the PEX5 long isoform.
A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.
Martin de Fourchambault E, Callens N, Saliou JM, Fourcot M, Delos O, Barois N, Thorel Q, Ramirez S, Bukh J, Cocquerel L, Bertrand-Michel J, Marot G, Sebti Y, Dubuisson J, Rouillé Y
Frontiers in microbiology 2023;14:1254728
Frontiers in microbiology 2023;14:1254728
Comparison of human PEX knockout cell lines suggests a dual role of PEX1 in peroxisome biogenesis.
Ott J, Sehr J, Schmidt N, Schliebs W, Erdmann R
Biological chemistry 2023 Feb 23;404(2-3):209-219
Biological chemistry 2023 Feb 23;404(2-3):209-219
Circular RNA Sec61 subunit alpha isoform 1 by competitive absorption of microRNA-513a-5p mediates peroxisomal biogenesis factor 5 expression and promotes the malignant phenotype of non-small cell lung cancer.
Duan ZP, Yu XJ, Wei HL
The Kaohsiung journal of medical sciences 2023 Apr;39(4):326-336
The Kaohsiung journal of medical sciences 2023 Apr;39(4):326-336
Silencing PEX26 as an unconventional mode to kill drug-resistant cancer cells and forestall drug resistance.
Dahabieh MS, Huang F, Goncalves C, Flores González RE, Prabhu S, Bolt A, Di Pietro E, Khoury E, Heath J, Xu ZY, Rémy-Sarrazin J, Mann KK, Orthwein A, Boisvert FM, Braverman N, Miller WH, Del Rincón SV
Autophagy 2022 Mar;18(3):540-558
Autophagy 2022 Mar;18(3):540-558
PEX5 prevents cardiomyocyte hypertrophy via suppressing the redox-sensitive signaling pathways MAPKs and STAT3.
Wang M, Li J, Ding Y, Cai S, Li Z, Liu P
European journal of pharmacology 2021 Sep 5;906:174283
European journal of pharmacology 2021 Sep 5;906:174283
Pkd1 Mutation Has No Apparent Effects on Peroxisome Structure or Lipid Metabolism.
Terabayashi T, Menezes LF, Zhou F, Cai H, Walter PJ, Garraffo HM, Germino GG
Kidney360 2021 Oct 28;2(10):1576-1591
Kidney360 2021 Oct 28;2(10):1576-1591
Resolving monocytes generated through TRAM deletion attenuate atherosclerosis.
Geng S, Zhang Y, Yi Z, Lu R, Li L
JCI insight 2021 Oct 22;6(20)
JCI insight 2021 Oct 22;6(20)
Aging lowers PEX5 levels in cortical neurons in male and female mouse brains.
Uzor NE, Scheihing DM, Kim GS, Moruno-Manchon JF, Zhu L, Reynolds CR, Stephenson JM, Holmes A, McCullough LD, Tsvetkov AS
Molecular and cellular neurosciences 2020 Sep;107:103536
Molecular and cellular neurosciences 2020 Sep;107:103536
Ceramide regulates interaction of Hsd17b4 with Pex5 and function of peroxisomes.
Zhu Z, Chen J, Wang G, Elsherbini A, Zhong L, Jiang X, Qin H, Tripathi P, Zhi W, Spassieva SD, Morris AJ, Bieberich E
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Oct;1864(10):1514-1524
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Oct;1864(10):1514-1524
ATM functions at the peroxisome to induce pexophagy in response to ROS.
Zhang J, Tripathi DN, Jing J, Alexander A, Kim J, Powell RT, Dere R, Tait-Mulder J, Lee JH, Paull TT, Pandita RK, Charaka VK, Pandita TK, Kastan MB, Walker CL
Nature cell biology 2015 Oct;17(10):1259-1269
Nature cell biology 2015 Oct;17(10):1259-1269
A novel type of rhizomelic chondrodysplasia punctata, RCDP5, is caused by loss of the PEX5 long isoform.
Barøy T, Koster J, Strømme P, Ebberink MS, Misceo D, Ferdinandusse S, Holmgren A, Hughes T, Merckoll E, Westvik J, Woldseth B, Walter J, Wood N, Tvedt B, Stadskleiv K, Wanders RJ, Waterham HR, Frengen E
Human molecular genetics 2015 Oct 15;24(20):5845-54
Human molecular genetics 2015 Oct 15;24(20):5845-54
A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.
Zhang J, Kim J, Alexander A, Cai S, Tripathi DN, Dere R, Tee AR, Tait-Mulder J, Di Nardo A, Han JM, Kwiatkowski E, Dunlop EA, Dodd KM, Folkerth RD, Faust PL, Kastan MB, Sahin M, Walker CL
Nature cell biology 2013 Oct;15(10):1186-96
Nature cell biology 2013 Oct;15(10):1186-96
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PEX5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PEX5. This antibody recognizes human, mouse, rat antigen. The PEX5 antibody has been validated for the following applications: ELISA, WB analysis.
