313401

antibody from BioLegend
Targeting: UFD1 UFD1L
Provider product page for 313401
Western blot
Immunoprecipitation
Flow cytometry

Antibody data

Product number
313401 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#313401, RRID:AB_314994
Product name
Purified anti-human/mouse ZAP-70
Antibody type
Monoclonal
Antigen
GST-fusion protein corresponding to residues 282-307 of human ZAP-70
Description
ZAP-70 is a 70 kD protein tyrosine kinase associated with the zeta chain of the T cell receptor. It is expressed in T cells and NK cells and has been shown to be involved in T cell signaling. Defects in ZAP-70 have been linked to selective T cell defects. The ZAP-70 kinase undergoes multiple phosphorylation events after T cell receptor engagement and interacts with a number of proteins involved in signal transduction. Recently, ZAP-70 has been identified as an important prognostic marker in B-cell chronic lymphocytic leukemia (B-CLL). The 1E7.2 monoclonal antibody recognizes human and mouse ZAP-70 and has been shown to be useful for flow cytometry, Western blotting, and immunoprecipitation.
Reactivity
Human, Mouse
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C.
UFD1 protein structure - 313401 shown in red.