Antibody data
- Antibody Data
- Antigen structure
- References [41]
- Comments [0]
- Validations
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 20785-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- GLAST antibody
- Antibody type
- Polyclonal
- Description
- GLAST antibody (Cat. #20785-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Functional nutrient-genetic profiling reveals biotin and FBXW7 are essential to bypass glutamine addiction.
Neuronal PPP2R5C in plasma is a potential biomarker for early diagnosis of Alzheimer's disease.
Jianpi Jiedu formula modulates glutamine metabolism to inhibit colorectal cancer liver metastasis.
SA supplementation during lactation promotes learning and memory by reducing H3K27me3 levels.
Astrocytic PYGM attenuates tau pathology by promoting lactate-mediated neuroprotection.
Panax notoginseng Flower Extract Attenuates Pentylenetetrazole-Induced Epilepsy by Restoring Glutamate Homeostasis.
Permethrin induces epileptic susceptibility via activation of Na(+) channels and rise in glutamate.
Molecular signature of primate astrocytes reveals pathways and regulatory changes contributing to human brain evolution.
Astroglial membrane camouflaged Ptbp1 siRNA delivery hinders glutamate homeostasis via SDH/Nrf2 pathway.
Hypothermia Shifts Neurodegeneration Phenotype in Neonatal Human Hypoxic-Ischemic Encephalopathy but Not in Related Piglet Models: Possible Relationship to Toxic Conformer and Intrinsically Disordered Prion-like Protein Accumulation.
The m6A reader YTHDC2 promotes the pathophysiology of temporal lobe epilepsy by modulating SLC7A11-dependent glutamate dysregulation in astrocytes.
YTHDF1 regulates GID8-mediated glutamine metabolism to promote colorectal cancer progression in m6A-dependent manner.
Induction of tau pathology and motor dysfunction in mice by urinary exosomes from progressive supranuclear palsy patients.
Metabolic regulation of the glioblastoma stem cell epitranscriptome by malate dehydrogenase 2.
Astrocytic lactoferrin deficiency augments MPTP-induced dopaminergic neuron loss by disturbing glutamate/calcium and ER-mitochondria signaling.
Neuronal small extracellular vesicles carrying miR-181c-5p contribute to the pathogenesis of epilepsy by regulating the protein kinase C-δ/glutamate transporter-1 axis in astrocytes.
BACH1 changes microglial metabolism and affects astrogenesis during mouse brain development.
Regulatory roles of histamine receptor in astrocytic glutamate clearance under conditions of increased glucose variability.
β-Hydroxybutyrate enhances astrocyte glutamate uptake through EAAT1 expression regulation.
Brain-Derived Exosomal CircRNAs in Plasma Serve as Diagnostic Biomarkers for Acute Ischemic Stroke.
FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer.
Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brain.
In Vitro Functional Characterization of Type-I Taste Bud Cells as Monocytes/Macrophages-like Which Secrete Proinflammatory Cytokines.
Repeated sevoflurane exposures inhibit neurogenesis by inducing the upregulation of glutamate transporter 1 in astrocytes.
Microglia-Derived Spp1 Promotes Pathological Retinal Neovascularization via Activating Endothelial Kit/Akt/mTOR Signaling.
Distinguished Functions of Microglia in the Two Stages of Oxygen-Induced Retinopathy: A Novel Target in the Treatment of Ischemic Retinopathy.
Cyanidin Chloride Improves LPS-Induced Depression-Like Behavior in Mice by Ameliorating Hippocampal Inflammation and Excitotoxicity.
Endothelial Cells Mediated by UCP2 Control the Neurogenic-to-Astrogenic Neural Stem Cells Fate Switch During Brain Development.
L-Theanine Regulates the Abundance of Amino Acid Transporters in Mice Duodenum and Jejunum via the mTOR Signaling Pathway.
SOX2 is essential for astrocyte maturation and its deletion leads to hyperactive behavior in mice.
Intracellular Staphylococcus aureus Infection Decreases Milk Protein Synthesis by Preventing Amino Acid Uptake in Bovine Mammary Epithelial Cells.
iTRAQ-based proteomic analysis after mesenchymal stem cell line transplantation for ischemic stroke.
RAGE Signaling pathway in hippocampus dentate gyrus involved in GLT-1 decrease induced by chronic unpredictable stress in rats.
Functional validation of a human GLUD2 variant in a murine model of Parkinson's disease.
Expression Patterns of Inducible Cre Recombinase Driven by Differential Astrocyte-Specific Promoters in Transgenic Mouse Lines.
Exosomal and extracellular HMGB1 have opposite effects on SASH1 expression in rat astrocytes and glioma C6 cells.
Ginsenoside Rb1 prevents MPTP-induced changes in hippocampal memory via regulation of the α-synuclein/PSD-95 pathway.
H2A.Z.1 crosstalk with H3K56-acetylation controls gliogenesis through the transcription of folate receptor.
Ginsenoside Rb1 confers neuroprotection via promotion of glutamate transporters in a mouse model of Parkinson's disease.
RNF20 controls astrocytic differentiation through epigenetic regulation of STAT3 in the developing brain.
Impact of Reduced Cerebellar EAAT Expression on Purkinje Cell Firing Pattern of NPC1-deficient Mice.
Lisci M, Vericel F, Liu Y, Gallart-Ayala H, Ivanisevic J, Skinner OS, Jourdain AA
Molecular cell 2026 Mar 5;86(5):901-916.e10
Molecular cell 2026 Mar 5;86(5):901-916.e10
Neuronal PPP2R5C in plasma is a potential biomarker for early diagnosis of Alzheimer's disease.
Luo S, Liu H, Xiao T, Li Y, Liu X, Xiao X, Liao X, Liu Y, Zhou Y, Wang JL, Guo J, Tu T, Yan X, Tang B, Zhang Z, Jiao B, Shen L
Cell reports. Medicine 2026 Mar 17;7(3):102631
Cell reports. Medicine 2026 Mar 17;7(3):102631
Jianpi Jiedu formula modulates glutamine metabolism to inhibit colorectal cancer liver metastasis.
Han Y, Ouyang Y, Pu Y, Zhou P, Yang L, Deng W, Song Q, Ji Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157680
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157680
SA supplementation during lactation promotes learning and memory by reducing H3K27me3 levels.
Huang C, Ai S, Wang M, Li C, Wang K, Nie M, Zhang H, Gu X, Wang HL
Journal of advanced research 2026 Feb;80:301-316
Journal of advanced research 2026 Feb;80:301-316
Astrocytic PYGM attenuates tau pathology by promoting lactate-mediated neuroprotection.
Cao J, Meng J, Chen Y, Tang Z, Wang Y, Li K, Zhang X, Luo H, Li H, Wang Z, Zhang YW
Alzheimer's & dementia : the journal of the Alzheimer's Association 2026 Feb;22(2):e71202
Alzheimer's & dementia : the journal of the Alzheimer's Association 2026 Feb;22(2):e71202
Panax notoginseng Flower Extract Attenuates Pentylenetetrazole-Induced Epilepsy by Restoring Glutamate Homeostasis.
Zhao Y, Zhu F, Xie J, Wang Y, Matsabisa M, Tang M
Brain sciences 2025 Oct 15;15(10)
Brain sciences 2025 Oct 15;15(10)
Permethrin induces epileptic susceptibility via activation of Na(+) channels and rise in glutamate.
Su M, Zhang Y, Feng Z, Li W, Liu Y, Xu C, Zhao C, Kwan P, Tian X, Li L
Communications biology 2025 Nov 24;8(1):1644
Communications biology 2025 Nov 24;8(1):1644
Molecular signature of primate astrocytes reveals pathways and regulatory changes contributing to human brain evolution.
Ciuba K, Piotrowska A, Chaudhury D, Dehingia B, Duński E, Behr R, Soroczyńska K, Czystowska-Kuźmicz M, Abbas M, Bulanda E, Gawlik-Zawiślak S, Pietrzak S, Figiel I, Włodarczyk J, Verkhratsky A, Niedbała M, Kaspera W, Wypych T, Wilczyński B, Pękowska A
Cell stem cell 2025 Mar 6;32(3):426-444.e14
Cell stem cell 2025 Mar 6;32(3):426-444.e14
Astroglial membrane camouflaged Ptbp1 siRNA delivery hinders glutamate homeostasis via SDH/Nrf2 pathway.
Liu Y, Ren J, Zhang W, Ding L, Ma R, Zhang M, Zheng S, Liang R, Zhang Y
Biomaterials 2025 Jan;312:122707
Biomaterials 2025 Jan;312:122707
Hypothermia Shifts Neurodegeneration Phenotype in Neonatal Human Hypoxic-Ischemic Encephalopathy but Not in Related Piglet Models: Possible Relationship to Toxic Conformer and Intrinsically Disordered Prion-like Protein Accumulation.
Martin LJ, Lee JK, Niedzwiecki MV, Amrein Almira A, Javdan C, Chen MW, Olberding V, Brown SM, Park D, Yohannan S, Putcha H, Zheng B, Garrido A, Benderoth J, Kisner C, Ghaemmaghami J, Northington FJ, Kratimenos P
Cells 2025 Apr 12;14(8)
Cells 2025 Apr 12;14(8)
The m6A reader YTHDC2 promotes the pathophysiology of temporal lobe epilepsy by modulating SLC7A11-dependent glutamate dysregulation in astrocytes.
Zhang K, Yang Z, Yang Z, Du L, Zhou Y, Fu S, Wang X, Li X, Liu D, He X
Theranostics 2024;14(14):5551-5570
Theranostics 2024;14(14):5551-5570
YTHDF1 regulates GID8-mediated glutamine metabolism to promote colorectal cancer progression in m6A-dependent manner.
Han Y, Pu Y, Liu X, Liu Z, Chen Y, Tang L, Zhou J, Song Q, Ji Q
Cancer letters 2024 Oct 1;601:217186
Cancer letters 2024 Oct 1;601:217186
Induction of tau pathology and motor dysfunction in mice by urinary exosomes from progressive supranuclear palsy patients.
Li Q, Liu H, Zhu Q, Zhang R, Liang D, Zhang J, Jin R, Chen Y, Qin C, Teng J
Brain research bulletin 2024 Oct 1;216:111046
Brain research bulletin 2024 Oct 1;216:111046
Metabolic regulation of the glioblastoma stem cell epitranscriptome by malate dehydrogenase 2.
Lv D, Dixit D, Cruz AF, Kim LJY, Duan L, Xu X, Wu Q, Zhong C, Lu C, Gersey ZC, Gimple RC, Xie Q, Yang K, Liu X, Fang X, Wu X, Kidwell RL, Wang X, Bao S, He HH, Locasale JW, Agnihotri S, Rich JN
Cell metabolism 2024 Nov 5;36(11):2419-2436.e8
Cell metabolism 2024 Nov 5;36(11):2419-2436.e8
Astrocytic lactoferrin deficiency augments MPTP-induced dopaminergic neuron loss by disturbing glutamate/calcium and ER-mitochondria signaling.
Xu SF, Cui JH, Liu X, Pang ZQ, Bai CY, Jiang C, Luan C, Li YP, Zhao Y, You YM, Guo C
Free radical biology & medicine 2024 Nov 20;225:374-387
Free radical biology & medicine 2024 Nov 20;225:374-387
Neuronal small extracellular vesicles carrying miR-181c-5p contribute to the pathogenesis of epilepsy by regulating the protein kinase C-δ/glutamate transporter-1 axis in astrocytes.
Ma L, Wu Q, You Y, Zhang P, Tan D, Liang M, Huang Y, Gao Y, Ban Y, Chen Y, Yuan J
Glia 2024 Jun;72(6):1082-1095
Glia 2024 Jun;72(6):1082-1095
BACH1 changes microglial metabolism and affects astrogenesis during mouse brain development.
Wang Y, Wang W, Su L, Ji F, Zhang M, Xie Y, Zhang T, Jiao J
Developmental cell 2024 Jan 8;59(1):108-124.e7
Developmental cell 2024 Jan 8;59(1):108-124.e7
Regulatory roles of histamine receptor in astrocytic glutamate clearance under conditions of increased glucose variability.
Zhou Y, Xie W, Kong C, Luo W, Wei H, Zheng J
Biochemical pharmacology 2024 Dec;230(Pt 3):116611
Biochemical pharmacology 2024 Dec;230(Pt 3):116611
β-Hydroxybutyrate enhances astrocyte glutamate uptake through EAAT1 expression regulation.
Shang S, Wang L, Lu X
Molecular and cellular neurosciences 2024 Dec;131:103959
Molecular and cellular neurosciences 2024 Dec;131:103959
Brain-Derived Exosomal CircRNAs in Plasma Serve as Diagnostic Biomarkers for Acute Ischemic Stroke.
Jiang X, Zhang R, Lu G, Zhou Y, Li J, Jiang X, Gu S, Liang H, Wang J
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 Apr 22;19(1):15
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 Apr 22;19(1):15
FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer.
Chen C, Ye L, Yi J, Liu T, Li Z
Breast cancer research and treatment 2023 Oct;201(3):515-533
Breast cancer research and treatment 2023 Oct;201(3):515-533
Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brain.
Wang Y, Su L, Wang W, Zhao J, Wang Y, Li S, Liu Y, Chai R, Li X, Teng Z, Liu C, Hu B, Ji F, Jiao J
Cell proliferation 2023 May;56(5):e13447
Cell proliferation 2023 May;56(5):e13447
In Vitro Functional Characterization of Type-I Taste Bud Cells as Monocytes/Macrophages-like Which Secrete Proinflammatory Cytokines.
Hichami A, Saidi H, Khan AS, Degbeni P, Khan NA
International journal of molecular sciences 2023 Jun 19;24(12)
International journal of molecular sciences 2023 Jun 19;24(12)
Repeated sevoflurane exposures inhibit neurogenesis by inducing the upregulation of glutamate transporter 1 in astrocytes.
Kong F, Zhang Y, Wang T, Zhong L, Feng C, Wu Y
The European journal of neuroscience 2023 Jan;57(2):217-232
The European journal of neuroscience 2023 Jan;57(2):217-232
Microglia-Derived Spp1 Promotes Pathological Retinal Neovascularization via Activating Endothelial Kit/Akt/mTOR Signaling.
Bai Q, Wang X, Yan H, Wen L, Zhou Z, Ye Y, Jing Y, Niu Y, Wang L, Zhang Z, Su J, Chang T, Dou G, Wang Y, Sun J
Journal of personalized medicine 2023 Jan 11;13(1)
Journal of personalized medicine 2023 Jan 11;13(1)
Distinguished Functions of Microglia in the Two Stages of Oxygen-Induced Retinopathy: A Novel Target in the Treatment of Ischemic Retinopathy.
Zhou Z, Jing Y, Niu Y, Chang T, Sun J, Guo C, Wang Y, Dou G
Life (Basel, Switzerland) 2022 Oct 21;12(10)
Life (Basel, Switzerland) 2022 Oct 21;12(10)
Cyanidin Chloride Improves LPS-Induced Depression-Like Behavior in Mice by Ameliorating Hippocampal Inflammation and Excitotoxicity.
Qu D, Ye Z, Zhang W, Dai B, Chen G, Wang L, Shao X, Xiang A, Lu Z, Shi J
ACS chemical neuroscience 2022 Nov 2;13(21):3023-3033
ACS chemical neuroscience 2022 Nov 2;13(21):3023-3033
Endothelial Cells Mediated by UCP2 Control the Neurogenic-to-Astrogenic Neural Stem Cells Fate Switch During Brain Development.
Wang W, Su L, Wang Y, Li C, Ji F, Jiao J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jun;9(18):e2105208
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jun;9(18):e2105208
L-Theanine Regulates the Abundance of Amino Acid Transporters in Mice Duodenum and Jejunum via the mTOR Signaling Pathway.
Liu K, Peng Y, Lin L, Gong Z, Xiao W, Li Y
Nutrients 2022 Dec 28;15(1)
Nutrients 2022 Dec 28;15(1)
SOX2 is essential for astrocyte maturation and its deletion leads to hyperactive behavior in mice.
Wang Y, Zhang S, Lan Z, Doan V, Kim B, Liu S, Zhu M, Hull VL, Rihani S, Zhang CL, Gray JA, Guo F
Cell reports 2022 Dec 20;41(12):111842
Cell reports 2022 Dec 20;41(12):111842
Intracellular Staphylococcus aureus Infection Decreases Milk Protein Synthesis by Preventing Amino Acid Uptake in Bovine Mammary Epithelial Cells.
Chen Y, Ma Y, Ji Q, Yang X, Feng X, Yao R, Cheng X, Li T, Wang Y, Wang Z
Frontiers in veterinary science 2021;8:756375
Frontiers in veterinary science 2021;8:756375
iTRAQ-based proteomic analysis after mesenchymal stem cell line transplantation for ischemic stroke.
Mitaki S, Nagai A, Wada Y, Onoda K, Md Sheikh A, Adachi E, Matsumoto KI, Yamaguchi S
Brain research 2020 Sep 1;1742:146900
Brain research 2020 Sep 1;1742:146900
RAGE Signaling pathway in hippocampus dentate gyrus involved in GLT-1 decrease induced by chronic unpredictable stress in rats.
Yang F, Wang H, Chen H, Ran D, Tang Q, Weng P, Sun Y, Jiang W
Brain research bulletin 2020 Oct;163:49-56
Brain research bulletin 2020 Oct;163:49-56
Functional validation of a human GLUD2 variant in a murine model of Parkinson's disease.
Zhang W, Gong J, Ding L, Zhang Z, Pan X, Chen X, Guo W, Zhang X, Yang X, Peng G, Lin Y, Gao F, Li Y, Zhu X, Xuan A, Wang S, Sun X, Zhang Y, Xu P
Cell death & disease 2020 Oct 22;11(10):897
Cell death & disease 2020 Oct 22;11(10):897
Expression Patterns of Inducible Cre Recombinase Driven by Differential Astrocyte-Specific Promoters in Transgenic Mouse Lines.
Hu NY, Chen YT, Wang Q, Jie W, Liu YS, You QL, Li ZL, Li XW, Reibel S, Pfrieger FW, Yang JM, Gao TM
Neuroscience bulletin 2020 May;36(5):530-544
Neuroscience bulletin 2020 May;36(5):530-544
Exosomal and extracellular HMGB1 have opposite effects on SASH1 expression in rat astrocytes and glioma C6 cells.
Ma C, Chen H, Zhang S, Yan Y, Wu R, Wang Y, Liu Y, Yang L, Liu M
Biochemical and biophysical research communications 2019 Oct 15;518(2):325-330
Biochemical and biophysical research communications 2019 Oct 15;518(2):325-330
Ginsenoside Rb1 prevents MPTP-induced changes in hippocampal memory via regulation of the α-synuclein/PSD-95 pathway.
Qu S, Meng X, Liu Y, Zhang X, Zhang Y
Aging 2019 Apr 4;11(7):1934-1964
Aging 2019 Apr 4;11(7):1934-1964
H2A.Z.1 crosstalk with H3K56-acetylation controls gliogenesis through the transcription of folate receptor.
Su L, Xia W, Shen T, Liang Q, Wang W, Li H, Jiao J
Nucleic acids research 2018 Sep 28;46(17):8817-8831
Nucleic acids research 2018 Sep 28;46(17):8817-8831
Ginsenoside Rb1 confers neuroprotection via promotion of glutamate transporters in a mouse model of Parkinson's disease.
Zhang YL, Liu Y, Kang XP, Dou CY, Zhuo RG, Huang SQ, Peng L, Wen L
Neuropharmacology 2018 Mar 15;131:223-237
Neuropharmacology 2018 Mar 15;131:223-237
RNF20 controls astrocytic differentiation through epigenetic regulation of STAT3 in the developing brain.
Liang Q, Xia W, Li W, Jiao J
Cell death and differentiation 2018 Feb;25(2):294-306
Cell death and differentiation 2018 Feb;25(2):294-306
Impact of Reduced Cerebellar EAAT Expression on Purkinje Cell Firing Pattern of NPC1-deficient Mice.
Rabenstein M, Peter F, Rolfs A, Frech MJ
Scientific reports 2018 Feb 20;8(1):3318
Scientific reports 2018 Feb 20;8(1):3318
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The GLAST antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human GLAST. This antibody recognizes human, mouse, rat antigen. The GLAST antibody has been validated for the following applications: ELISA, IHC, WB analysis.