APOBEC1

This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015]

Description

Apolipoprotein B mRNA editing enzyme catalytic subunit 1

Tissue specificity

Tissue enriched (intestine)

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

12 (7649400 - 7665908)

Ensembl ID

ENSG00000111701  (ver. 103.38)

Orthologs

Mouse Apobec1: ENSMUSG00000040613

UniProt

P41238

neXtProt

NX_P41238

Human splice variants
Mouse splice variants

Protein structure