Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 354202 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#354202, RRID:AB_11124104
- Product name
- Purified anti-human CD303 (BDCA-2)
- Antibody type
- Monoclonal
- Antigen
- CD303
- Description
- CD303, also known as BDCA-2 and CLEC4C, is a 38 kD type II transmembrane glycoprotein. It is a member of the C-type lectin superfamily. CD303 is expressed by plasmacytoid dendritic cells (pDCs) and is involved in cell adhesion, signaling, and antigen capture and processing. Crosslinking of CD303 inhibits the production of IFN-α/β and TLR-9 induced pDCs maturation.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral mononuclear cells were stained with purified CD303 (clone 201A, top) or purified mouse IgG2a, κ isotype control (bottom), followed by anti-mouse IgG PE and CD123 APC. Data shown was gated on the lymphocyte and monocyte populations.
- Conjugate
- Unconjugated