RA0487

antibody from Oursmab

Targeting: AMH MIS

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0487

Provider

Oursmab

Product name

Imalumab (Biosimilar Reference Antibody) (MIF)

Antibody type

Monoclonal

Description

Imalumab (development code BAX-069) is an investigational, fully human monoclonal antibody developed for the treatment of solid tumors and inflammatory conditions. It functions as a targeted inhibitor of Oxidized Macrophage Migration Inhibitory Factor (oxMIF). By binding with high affinity to a specific oxidized isoform of the MIF cytokine, imalumab selectively neutralizes its pathogenic activity. This blockade prevents oxMIF from interacting with its receptors, CD74 and CXCR2/4, thereby inhibiting the downstream pro-inflammatory and pro-tumorigenic signaling pathways that promote cancer cell survival, proliferation, angiogenesis, and immune evasion, as well as chronic inflammation.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.