Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B9146 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Rabbit Anti-Human TBX1 Polyclonal Antibody
- Antibody type
- Polyclonal
- Description
- This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Concentration
- Lot specific
- Storage
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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