Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS5633 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- BST1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 120-165 of Human BST1.
- Description
- BST-1 (bone marow stromal antigen-1) has been identified as a surface molecule that is GPI-anchored to the cell membrane of stromal cells. Both ADP-ribosyl cyclase and cADPR hydrolase activites have been demonstrated by BST-1. cADPR activity is a potential regulator of insulin secretion in pancreatic beta cells. Most pancreatic islet cells express BST-1, indicating a link between BST-1 and insulin secretion. BST-1 expression has also been found in a wide range of tissues including umbilical vein endothelial cells, monocytes and granulocytes. BST-1 expression in thymus tissue and on B and T cell progenitors undergoing gene rearrangement implicates BST-1 as a useful marker for lymphoid progenitor cells that are initiating gene rearrangement of their antigen receptors. BST-1 has also been shown to facilitate B cell growth and may act as a receptor.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of BST1 pAb at 1:500 dilutionLane1:Hela cell lysateLane2:Raw264.7 cell lysateLane3:H9C2 cell lysate