DCABH-6825

antibody from Creative Diagnostics

Targeting: TXNRD2 SELZ, TR, TR3, TRXR2

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

DCABH-6825

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DCABH-6825, RRID:AB_2480230

Product name

Rabbit Anti-Human TXNRD2 polyclonal antibody

Antibody type

Polyclonal

Description

The reduced form of thioredoxin serves as a hydrogen donor, contributes to the up-regulation of various transcription factors and binds to and inhibits MAPKKK activity. Oxidized thioredoxin is converted back to the reduced form by Thioredoxin Reductase (TrxR2) , a redox active enzyme. There are two distinct isoforms in mammalian cells, TrxR1, a cytosolic protein and TrxR2, almost exclusively a mitochondrial protein. TrxR expression is induced in several tumors.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Storage

2-8°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.