Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA009084 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA009084, RRID:AB_1079967
- Product name
- Anti-SIGLEC6
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human SIGLEC6, Gene description: sialic acid binding Ig-like lectin 6, Alternative Gene Names: CD327, CD33L, CD33L1, OB-BP1, SIGLEC-6, Validated applications: IHC, WB, Uniprot ID: O43699, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Highly efficient generation of self-renewing trophoblast from human pluripotent stem cells
Siglec-6 as a therapeutic target for cell migration and adhesion in chronic lymphocytic leukemia
Functional Inhibitory Siglec-6 Is Upregulated in Human Colorectal Cancer-Associated Mast Cells
Slamecka J, Ryu S, Tristan C, Chu P, Weber C, Deng T, Gedik Y, Ormanoglu P, Voss T, Simeonov A, SingeƧ I
iScience 2024;27(10):110874
iScience 2024;27(10):110874
Siglec-6 as a therapeutic target for cell migration and adhesion in chronic lymphocytic leukemia
Nunes J, Tafesse R, Mao C, Purcell M, Mo X, Zhang L, Long M, Cyr M, Rader C, Muthusamy N
Nature Communications 2024;15(1)
Nature Communications 2024;15(1)
Functional Inhibitory Siglec-6 Is Upregulated in Human Colorectal Cancer-Associated Mast Cells
Yu Y, Blokhuis B, Diks M, Keshavarzian A, Garssen J, Redegeld F
Frontiers in Immunology 2018;9
Frontiers in Immunology 2018;9
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human placenta and liver tissues using HPA009084 antibody. Corresponding SIGLEC6 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol