Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- MA5-28140 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- SIGLEC5/SIGLEC14 Monoclonal Antibody (1A5)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- This antibody recognizes human Siglec-5 (Sialic acid-binding Ig-like lectin 5), otherwise known as CD170, a novel sialic-acid-binding Ig-like lectin, and member of the Ig superfamily, expressed by dendritic cells (DCs), activated macrophages, neutrophils, and cells of the monocyte/myeloid lineage.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 1A5
- Vial size
- 100 µg
- Concentration
- 1 mg/mL
- Storage
- 4°C or -20°C if preferred
Submitted references Moraxella catarrhalis evades neutrophil oxidative stress responses providing a safer niche for nontypeable Haemophilus influenzae.
Nicchi S, Giusti F, Carello S, Utrio Lanfaloni S, Tavarini S, Frigimelica E, Ferlenghi I, Rossi Paccani S, Merola M, Delany I, Scarlato V, Maione D, Brettoni C
iScience 2022 Mar 18;25(3):103931
iScience 2022 Mar 18;25(3):103931
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Supportive validation
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- Invitrogen Antibodies (provider)
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- Experimental details
- Flow cytometry of SIGLEC5/SIGLEC14 in human peripheral blood monocytes. Sample was incubated with SIGLEC5/SIGLEC14 monoclonal antibody (Product # MA5-28140), followed by Rabbit anti Mouse IgG - FITC.