Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- AF3065 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal LIR-8/CD85c/LILRB5 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human LILRB5/CD85c/LIR-8 in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant human (rh) LILRA4/ILT7 is observed and less than 15% cross-reactivity with rhILT3 and rhILT5 is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Coexpression of CD163 and CD141 identifies human circulating IL-10-producing dendritic cells (DC-10).
The extracellular interactome of the human adenovirus family reveals diverse strategies for immunomodulation.
The Leukocyte Immunoglobulin-Like Receptor Family Member LILRB5 Binds to HLA-Class I Heavy Chains.
Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development.
Comi M, Avancini D, Santoni de Sio F, Villa M, Uyeda MJ, Floris M, Tomasoni D, Bulfone A, Roncarolo MG, Gregori S
Cellular & molecular immunology 2020 Jan;17(1):95-107
Cellular & molecular immunology 2020 Jan;17(1):95-107
The extracellular interactome of the human adenovirus family reveals diverse strategies for immunomodulation.
Martinez-Martin N, Ramani SR, Hackney JA, Tom I, Wranik BJ, Chan M, Wu J, Paluch MT, Takeda K, Hass PE, Clark H, Gonzalez LC
Nature communications 2016 May 5;7:11473
Nature communications 2016 May 5;7:11473
The Leukocyte Immunoglobulin-Like Receptor Family Member LILRB5 Binds to HLA-Class I Heavy Chains.
Zhang Z, Hatano H, Shaw J, Olde Nordkamp M, Jiang G, Li D, Kollnberger S
PloS one 2015;10(6):e0129063
PloS one 2015;10(6):e0129063
Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development.
Zheng J, Umikawa M, Cui C, Li J, Chen X, Zhang C, Huynh H, Kang X, Silvany R, Wan X, Ye J, Cantó AP, Chen SH, Wang HY, Ward ES, Zhang CC
Nature 2012 May 30;485(7400):656-60
Nature 2012 May 30;485(7400):656-60
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of LILRB5/CD85c/LIR-8 in Human peripheral blood monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Goat Anti-Human LILRB5/CD85c/LIR-8 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3065, filled histogram) or control antibody (Catalog # AB-108-C, open histogram), followed by Phycoerythrin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0107).