Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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Validation data
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- Product number
- 10-4013-25 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-Dectin-2 Antibody
- Antibody type
- Monoclonal
- Description
- Dectin-2 (C-type lectin domain family 6 member A) is a type II membrane receptor with an extracellular C-type lectin-like domain fold. Dectin-2 plays an important role in the host defense against C. albicans infection by inducing TH17 cell differentiation. It binds high-mannose carbohydrates in a Ca(2+)-dependent manner. In Dectin-2 glycosylation occurs at Asn131, Asn170. Dectin-2 has 2 isoforms produced by alternative splicing. Dectin-2 is strongly expressed in monocytes and weakly in B-cells and also expressed in spleen, tonsils, lymph node, lungs, leukocytes, dendritic cells and bone marrow.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
A partial length recombinant Dectin
-2 protein (amino acids 70-230) was
used as the immunogen for this ant
ibody.- Isotype
- IgG
- Antibody clone number
- ABM2H28
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of Dectin 2 Anti- Dectin 2 antibody (Clone: ABM2H28) was used at 2 µg/ml on Raw lysate.
- Protocol
- Protocol
Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of Dectin-2 in Renal Cell Carcinoma using Dectin-2 antibody (Clone: ABM2H28) at 5 µg/ml.
- Protocol
- Protocol
Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Intracellular flow analysis of Dectin-2 in human PBMC (Lymphocytes) using 0.5 µg/10^6 cells of Dectin-2 antibody (Clone: ABM2H28). Green represents isotype control; red represents anti-Dectin-2 antibody. Goat anti-mouse PE conjugate was used as secondary.
- Protocol
- Protocol