CABT-L1302

antibody from Creative Diagnostics

Targeting: FKBP1A FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE

Western blot (Recommended by provider)

Antibody Data

Product number

CABT-L1302

Provider

Creative Diagnostics

Product name

Rabbit Anti-Human FKBP12 monoclonal antibody, clone 2I49M3

Antibody type

Monoclonal

Description

FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.

Reactivity

Mouse, Rat, Hamster

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2I49M3

Concentration

0.5 mg/ml

Storage

-20°C, Avoid Freeze/Thaw Cycles