APR06008G
antibody from Leading Biology
Targeting: FKBP1A
FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE
Antibody data
- Antibody Data
- Antigen structure
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- Product number
- APR06008G - Provider product page
- Provider
- Leading Biology
- Product name
- FKBP1A Antibody (C-term)
- Antibody type
- Polyclonal
- Description
- FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
- Reactivity
- Human
- Host
- Rabbit
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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